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Etofenamate

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Identification
Molecular formula
C18H18O3
CAS number
30544-47-9
IUPAC name
2-(1-ethyl-1-methyl-prop-2-ynoxy)carbonylbenzoic acid
State
State

At room temperature, etofenamate is in a liquid state.

Melting point (Celsius)
-3.00
Melting point (Kelvin)
270.15
Boiling point (Celsius)
210.00
Boiling point (Kelvin)
483.15
General information
Molecular weight
295.33g/mol
Molar mass
295.3320g/mol
Density
1.1088g/cm3
Appearence

Etofenamate typically appears as a clear to slightly yellow liquid. It is often used in topical formulations due to its physical properties.

Comment on solubility

Solubility of 2-(1-ethyl-1-methyl-prop-2-ynoxy)carbonylbenzoic acid

The solubility of 2-(1-ethyl-1-methyl-prop-2-ynoxy)carbonylbenzoic acid can be influenced by several factors, including its molecular structure, polarity, and the presence of functional groups. Here are some important points regarding its solubility:

  • Polarity: The compound contains both polar (carboxylic acid) and nonpolar (alkyl group) functional groups, which can lead to a moderate solubility profile.
  • pH Dependency: The solubility of carboxylic acids often increases with increasing pH due to deprotonation, which can enhance solubility in aqueous environments.
  • Solvents: It is generally more soluble in organic solvents like methanol, ethanol, or acetone due to its specific structural characteristics.
  • Temperature Influence: Increased temperature typically enhances the solubility of organic compounds, making it more soluble at elevated temperatures.

In conclusion, the solubility of 2-(1-ethyl-1-methyl-prop-2-ynoxy)carbonylbenzoic acid is likely to be moderate in polar organic solvents, while also being dependent on pH and temperature conditions. Understanding these parameters is essential for practical applications in both laboratory and industrial settings.

Interesting facts

Interesting Facts about 2-(1-Ethyl-1-methyl-prop-2-ynoxy)carbonylbenzoic Acid

This intriguing compound belongs to the category of **benzoic acids**, which are known for their diverse applications in both organic synthesis and medicinal chemistry. Here are some notable aspects of 2-(1-ethyl-1-methyl-prop-2-ynoxy)carbonylbenzoic acid:

  • Versatile Reagent: This compound can serve as a versatile building block for various synthetic routes, particularly in the creation of pharmaceutical intermediates.
  • Functional Groups: The presence of the carbonyl and ethynyl groups provides unique reactivity patterns, making it an interesting target for chemists looking to explore reaction mechanisms.
  • Biological Relevance: Compounds with similar structures have been investigated for their potential anti-inflammatory and analgesic properties, which could make this compound a candidate for further biological evaluation.
  • Structural Complexity: The compound features a complex structure that may enhance its bioavailability and specificity, openings for exploration in drug design.
  • Critical Research Topic: As a member of the larger family of substituted benzoic acids, this compound contributes to ongoing research in the fields of materials science and organic electronics.

In summary, the study of 2-(1-ethyl-1-methyl-prop-2-ynoxy)carbonylbenzoic acid not only enriches our understanding of benzoic acid derivatives but also highlights the potential for new synthetic pathways and applications in pharmaceuticals. As one expert noted, "The journey of synthesis can often lead to uncharted territories, revealing the hidden utility of compounds waiting to be explored."

Synonyms
PHTHALOFYNE
Ftalofyne
Whipcide
131-67-9
Methalofyne
Phthalofyne [USAN]
2-(3-methylpent-1-yn-3-yloxycarbonyl)benzoic acid
Ftalofyne [INN]
Mono(1-ethyl-1-methyl-2-propynyl) phthalate
3-Methyl-1-pentyn-3-yl acid phthalate
1-Pentyn-3-ol, 3-methyl-, phthalate monoester
Phthalic acid, 3-methyl-1-pentyn-3-yl monoester
1,2-Benzenedicarboxylic acid, mono(1-ethyl-1-methyl-2-propynyl) ester
TA9XO4D05J
DTXSID9057634
Ftalofyne (INN)
NSC-25614
Phthalofyne (USAN)
Phthalic acid, mono(1-ethyl-1-methyl-2-propynyl) ester
2-(((3-Methylpent-1-yn-3-yl)oxy)carbonyl)benzoic acid
2-{[(3-methylpent-1-yn-3-yl)oxy]carbonyl}benzoic acid
Ftalofynum
Ftalofino
Ftalofynum [INN-Latin]
Ftalofino [INN-Spanish]
16509-28-7
NSC 25614
UNII-TA9XO4D05J
Ftalofina
PHTHALOFYNE [MI]
FTALOFYNE [MART.]
SCHEMBL1651687
CHEMBL2107106
DTXCID0031423
PHTHALOFYNE [GREEN BOOK]
CZGIRAWWWHPJHM-UHFFFAOYSA-N
Tox21_113681
NSC295552
1-Ethyl-1-methyl-2-propynyl phthalate
DB11449
NSC-295552
NCGC00249905-01
CAS-131-67-9
NS00114086
D05468
Q27289871
2-([(1-Ethyl-1-methyl-2-propynyl)oxy]carbonyl)benzoic acid #
2-{[(1-ethyl-1-methyl-2-propynyl)oxy]carbonyl}benzoic acid