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Beauvericin

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Identification
Molecular formula
C45H57N7O10
CAS number
26048-05-5
IUPAC name
2-[[1-[2-[[2-[[2-[[2-[[2-[(2,4-diamino-4-oxo-butanoyl)amino]-5-guanidino-pentanoyl]amino]-3-methyl-butanoyl]amino]-3-(4-hydroxyphenyl)propanoyl]amino]-3-methyl-butanoyl]amino]-3-(1H-imidazol-5-yl)propanoyl]pyrrolidine-2-carbonyl]amino]-3-phenyl-propanoic acid
State
State

At room temperature, beauvericin is typically a solid.

Melting point (Celsius)
130.00
Melting point (Kelvin)
403.15
Boiling point (Celsius)
813.00
Boiling point (Kelvin)
1 086.15
General information
Molecular weight
783.98g/mol
Molar mass
783.9700g/mol
Density
1.3200g/cm3
Appearence

Beauvericin is a white to off-white powdery solid. It is often available in pure form for laboratory use.

Comment on solubility

Solubility of 2-[[1-[2-[[2-[[2-[[2-[(2,4-diamino-4-oxo-butanoyl)amino]-5-guanidino-pentanoyl]amino]-3-methyl-butanoyl]amino]-3-(4-hydroxyphenyl)propanoyl]amino]-3-methyl-butanoyl]amino]-3-(1H-imidazol-5-yl)propanoyl]pyrrolidine-2-carbonyl]amino]-3-phenyl-propanoic acid

The solubility of this complex compound, with the formula C45H57N7O10, can be analyzed based on its structural characteristics.

Factors Influencing Solubility

Several factors contribute to its solubility in various solvents:

  • Functional Groups: The presence of multiple amino groups and acidic features may enhance solubility in polar solvents, particularly water.
  • Molecular Weight: With a high molecular weight of 757.01 g/mol, solubility can be lower compared to lighter compounds.
  • Hydrophobic Regions: The numerous hydrophobic segments in the structure can hinder solubility in water, while promoting solubility in organic solvents.
  • pH Sensitivity: Since it contains an acidic component, the solubility may vary with changes in pH, affecting ionization.

Practical Considerations

In laboratory settings, it is often stated that:

"The solubility of a compound is as critical as its reactivity."

It is advisable to test solubility in:

  1. Water
  2. Ethanol
  3. Dimethyl sulfoxide (DMSO)

Due to its intricate structure, obtaining precise solubility data may require systematic experimentation. Understanding these aspects of solubility can lead to more effective applications in pharmaceuticals and biochemical contexts.

Interesting facts

Interesting Facts about 2-[[1-[2-[[2-[[2-[[2-[(2,4-diamino-4-oxo-butanoyl)amino]-5-guanidino-pentanoyl]amino]-3-methyl-butanoyl]amino]-3-(4-hydroxyphenyl)propanoyl]amino]-3-methyl-butanoyl]amino]-3-(1H-imidazol-5-yl)propanoyl]pyrrolidine-2-carbonyl]amino]-3-phenyl-propanoic acid

This compound is a fascinating example of complex organic chemistry, characterized by a substantial molecular structure that incorporates multiple functional groups. Here are some intriguing highlights:

  • Multi-functional Design: The compound features a series of amino acid derivatives and modifications, which contribute to its biological activity, resembling the structure and function of peptides.
  • Potential Applications: Due to its intricate structure, it may demonstrate properties relevant to drug design and therapeutic applications, especially in the biomedical field.
  • Proteins and Peptides Connection: Its resemblance to amino acids makes this compound a valuable model for understanding protein synthesis and interactions within biological systems.
  • Research Interest: This molecular architecture may attract researchers aiming to explore its interactions with specific biological targets, providing insight into metabolic pathways.

As one notable expert in the field emphasized, "The complexity of such molecules can lead to novel discoveries that bridge chemistry and biology." Understanding the properties and behaviors of compounds like this can significantly advance our knowledge in medicinal chemistry and drug formulation.

Given the intricate relationships among constituent elements, studying such compounds encourages the integration of various scientific disciplines and could potentially inspire new modes of treatment in pharmaceuticals.

Synonyms
Angiotensin II amide
53-73-6
Asn-Arg-Val-Tyr-Val-His-Pro-Phe
[Asn1,Val5]-ANGIOTENSIN II
Angiotensin (Ciba)
Angiotensin amide (USAN)
Angiotensinamid
NSC107678
BDBM410295
PAN-4036-V
US10370388, Compound Angiotensin
5-Valine-angiotensin II-.beta.-amide
L-Phenylalanine, N-[1-[N-[N-[N-[N-(N(sup2)-L-asparaginyl-L-arginyl)-L-valyl]-L-tyrosyl]-L-valyl]-L-histidyl]-L-prolyl]-
1-L-Asparagine-5-L-valine-angiotensin II
5-Valine-angiotensin II aspartic-.beta.-amide
D02939
Angiotensin II aspartic-.beta.-amide, 5-L-valine
1-Aspartic acid-.beta.-amide 5-valine-angiotensin II