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Benztropine mesylate

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Identification
Molecular formula
C21H25NO2·CH4O3S
CAS number
514-65-8
IUPAC name
(1R,5R)-3-benzhydryloxy-8-methyl-8-azabicyclo[3.2.1]octane;methanesulfonic acid
State
State

Solid at room temperature, generally found as a crystalline powder.

Melting point (Celsius)
120.00
Melting point (Kelvin)
393.00
Boiling point (Celsius)
275.00
Boiling point (Kelvin)
548.00
General information
Molecular weight
403.53g/mol
Molar mass
403.5290g/mol
Density
1.3000g/cm3
Appearence

The compound is typically a white to off-white crystalline powder.

Comment on solubility

Solubility of (1R,5R)-3-benzhydryloxy-8-methyl-8-azabicyclo[3.2.1]octane; methanesulfonic acid

The solubility characteristics of the compound (1R,5R)-3-benzhydryloxy-8-methyl-8-azabicyclo[3.2.1]octane; methanesulfonic acid can be quite fascinating. As a salt, it typically exhibits good solubility in polar solvents such as water due to the highly polar methanesulfonate group, which can interact favorably with water molecules.

There are several key points to consider regarding its solubility:

  • Water Solubility: The presence of the methanesulfonic acid moiety generally enhances the solubility in water and can contribute to the ionization of the compound.
  • Solvent Dependence: While soluble in aqueous solutions, solubility may vary significantly in organic solvents, possibly depending on the specific solvent polarity.
  • Temperature Influence: Like many compounds, increased temperature can foster higher solubility levels.

As it has structured components, the interactions between the hydrophobic aromatic groups and the surrounding solvent matrix can also play a crucial role in determining the overall solubility. Thus, one might conclude that understanding the solubility of (1R,5R)-3-benzhydryloxy-8-methyl-8-azabicyclo[3.2.1]octane; methanesulfonic acid is essential for optimizing its use in various applications, particularly those pertaining to pharmaceuticals.

Interesting facts

Interesting Facts about (1R,5R)-3-benzhydryloxy-8-methyl-8-azabicyclo[3.2.1]octane; methanesulfonic acid

(1R,5R)-3-benzhydryloxy-8-methyl-8-azabicyclo[3.2.1]octane; methanesulfonic acid is a fascinating compound with a unique structure and significant implications in various fields, including medicinal chemistry. Here are some intriguing aspects of this compound:

  • Structural Complexity: This compound features a bicyclic framework, which is notable for its rigidity and potential interactions in biological systems. The azabicyclo structure adds nitrogen, introducing unique properties that can influence the behavior of the molecule.
  • Pharmaceutical Relevance: Compounds in the azabicyclo family are often explored for their potential as pharmaceuticals. The specific stereochemistry of this compound may contribute to its efficacy and selectivity in biological activities, making it a valuable subject for drug design.
  • Mechanism of Action: Research into similar compounds has revealed diverse mechanisms, which can include effects on neurotransmitter receptors. This compound's interaction with the central nervous system could lead to novel therapeutic strategies.
  • Functionalization Opportunities: The presence of the benzhydryloxy group could provide avenues for further functionalization, potentially leading to new derivatives with enhanced properties or new applications. Chemists often capitalize on such groups to improve drug solubility or modify biological interactions.
  • Importance of Methanesulfonic Acid: The methanesulfonic acid moiety in this compound may play a crucial role in enhancing solubility and stability. Salts derived from methanesulfonic acid are also commonly used in pharmaceutical formulations to improve the bioavailability of active ingredients.

Overall, (1R,5R)-3-benzhydryloxy-8-methyl-8-azabicyclo[3.2.1]octane; methanesulfonic acid exemplifies the rich potential of organic chemistry in drug development and molecular design. It showcases how structural nuances can lead to significant biological implications.

Synonyms
BENZTROPINE MESYLATE
Benzotropine mesylate
132-17-2
Benztropine mesilate (JAN)
Benztropine mesylate (USP)
Cogentin (TN)
SCHEMBL1648656
MFCD00074784
AKOS026750089
PD121018
SW219521-1
D00778