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5-Aminoimidazole

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Identification
Molecular formula
C3H5N3
CAS number
51942-94-4
IUPAC name
1H-imidazol-5-amine
State
State

At room temperature, 5-Aminoimidazole is a solid. It is stable under normal conditions when kept dry and should be stored in a tightly closed container to avoid moisture absorption.

Melting point (Celsius)
164.00
Melting point (Kelvin)
437.00
Boiling point (Celsius)
230.00
Boiling point (Kelvin)
503.00
General information
Molecular weight
83.09g/mol
Molar mass
83.0890g/mol
Density
1.4000g/cm3
Appearence

5-Aminoimidazole typically appears as a white to off-white crystalline solid. It is not volatile and has a mild odor that is characteristic of organic compounds containing nitrogen.

Comment on solubility

Solubility of 1H-imidazol-5-amine (C3H5N3)

1H-imidazol-5-amine, also known as 1H-imidazole-5-amine, exhibits interesting solubility characteristics, largely influenced by its structural components. This compound is characterized by its amine and imidazole groups, which contribute to its **interaction with polar solvents**. Here are some key points regarding its solubility:

  • Water Solubility: 1H-imidazol-5-amine is moderately soluble in water. The presence of the amine group can facilitate hydrogen bonding with water molecules, enhancing solubility.
  • Solvent Compatibility: It tends to be more soluble in polar organic solvents such as methanol and ethanol compared to non-polar solvents.
  • Factors Affecting Solubility: Temperature and pH can significantly impact its solubility. An increase in temperature usually enhances solubility, while variations in pH can alter the protonation of the amine group, affecting overall solubility.

In solubility discussions, it’s often said that "like dissolves like," meaning that the polar nature of the 1H-imidazol-5-amine structure promotes better solubility in polar solvents rather than non-polar ones. Thus, understanding the solubility characteristics of this compound is crucial for its applications in various chemical contexts.

Interesting facts

Interesting Facts about 1H-imidazol-5-amine

1H-imidazol-5-amine, often referred to simply as an imidazole derivative, is a fascinating compound with numerous applications in various scientific fields. Here are some compelling points to consider:

  • Biological Significance: This compound is known for its role in various biochemical processes. Imidazole rings are often found in histidine, an important amino acid used by our bodies.
  • Catalytic Properties: The unique nitrogen-rich structure of 1H-imidazol-5-amine allows it to act as an effective catalyst in several chemical reactions, making it valuable in synthetic chemistry.
  • Pharmaceutical Applications: Compounds containing imidazole are frequently utilized in drug development. They can interact with biological systems in ways that are crucial for medicinal chemistry, particularly in the creation of antifungal and antibacterial agents.
  • Coordination Chemistry: The nitrogen atoms in the imidazole ring can serve as ligands in coordination compounds, enabling complex formation with transition metals. This feature is particularly useful in materials science and bioinorganic chemistry.
  • Environmental Relevance: Research has shown that imidazole derivatives may play a role in environmental chemistry, particularly in the understanding of soil chemistry and microbial activity.

In conclusion, 1H-imidazol-5-amine is more than just a simple compound; it acts as a bridge between many different areas of study, including biochemistry, medicinal chemistry, and environmental science. Its multifaceted nature continues to intrigue scientists and students alike, underscoring the importance of exploring such compounds in depth.

Synonyms
4-aminoimidazole
1H-Imidazol-4-amine
4919-03-3
1H-imidazol-5-amine
5-Aminoimidazole
7854BCQ2PS
4-(or 5-)aminoimidazole
IMIDAZOLE, 4-AMINO-
CHEBI:16607
DTXSID00197702
MFCD00235200
3h-imidazol-4-amine
1,3-diazolium-4-aminide
UNII-7854BCQ2PS
DTXCID20120193
QRZMXADUXZADTF-UHFFFAOYSA-N
BCP05277
MFCD10697825
AKOS005259860
AKOS006282285
MB08721
AS-56807
SY013999
NS00124781
C05239
EN300-177717
P20245
Q27101994