1H-Benzimidazol-2-yl(phenyl)methanol

Identification

Molecular formula

C₁₄H₁₂N₂O

CAS number

NULL

IUPAC name

1H-benzimidazol-2-yl(phenyl)methanol

State

At room temperature, 1H-Benzimidazol-2-yl(phenyl)methanol exists as a solid. Due to its stability, it maintains its solid-state under normal atmospheric conditions, making it easy to handle and store for laboratory uses.

Melting point (Celsius)

162.50

Melting point (Kelvin)

435.65

Boiling point (Celsius)

527.00

Boiling point (Kelvin)

800.15

General information

Molecular weight

238.27g/mol

Molar mass

238.2730g/mol

Density

1.2430g/cm³

Appearence

1H-Benzimidazol-2-yl(phenyl)methanol is a crystalline solid. The compound typically appears as a white to off-white powder, depending on its purity and specific form. It is often used in research and synthesis of more complex chemical entities due to its stability and versatile functional groups.

Comment on solubility

Solubility of 1H-benzimidazol-2-yl(phenyl)methanol

1H-benzimidazol-2-yl(phenyl)methanol, with the chemical formula C₁₄H₁₂N₂O, exhibits intriguing solubility characteristics that are influenced by both its structural features and the nature of the solvent. Here are some key points regarding its solubility:

Solvent Polarity: The solubility of this compound tends to be higher in polar solvents due to its potential for hydrogen bonding and dipole-dipole interactions. Common polar solvents include water and alcohols like methanol and ethanol.
Hydrophobic Interactions: The aromatic rings in its structure might lead to reduced solubility in non-polar solvents, such as hydrocarbons. This indicates a preference for interactions that can stabilize its polar components.
pH Dependence: The solubility can also vary with pH, as the presence of acidic or basic conditions may alter the ionization of functional groups, enhancing its solubility in either direction.
Temperature Effects: As with many organic compounds, increasing the temperature can enhance solubility by increasing molecular movement and interactions with solvent molecules.

In conclusion, while specific solubility data for 1H-benzimidazol-2-yl(phenyl)methanol in various solvents may not be extensively documented, understanding the interactions at play can provide insights into its behavior in different chemical environments. As a general observation, compounds with similar structures often favor solubility in polar environments, allowing for greater accessibility in pharmaceutical and chemical applications.

Interesting facts

Interesting Facts about 1H-benzimidazol-2-yl(phenyl)methanol

1H-benzimidazol-2-yl(phenyl)methanol is a fascinating compound that plays a significant role in various fields of chemistry and medicinal research. Here are some intriguing aspects of this compound:

Benzimidazole Core: The benzimidazole structure is a critical component, known for its biological activities and potential therapeutic applications. It is often found in many pharmaceuticals, which highlights its importance in drug design.
Diverse Applications: This compound has been studied for its applications in antimicrobial, antifungal, and even anticancer properties, showcasing its potential as a multifunctional therapeutic agent.
Mechanism of Action: Compounds like 1H-benzimidazol-2-yl(phenyl)methanol may function by modulating various biological pathways. Research has suggested it could influence cell apoptosis and inhibit cell proliferation in certain cancer cell lines.
Synthetic Versatility: The synthesis of this compound can involve various synthetic pathways, making it an excellent target for chemists seeking to explore new methodologies in organic synthesis.
Research Value: The study of such compounds provides insight into the development of new drugs and enhances our understanding of complex molecular interactions that can influence biological functions.

In summary, 1H-benzimidazol-2-yl(phenyl)methanol is more than just a chemical compound; it represents a valuable tool in the ongoing quest to discover new medicines and improve our understanding of chemical biology. Its distinct structure and the reactivity found within opens doors to innovative research opportunities.

Synonyms

1H-Benzimidazol-2-yl(phenyl)methanol

50-97-5

Hydrobenzole hydrochloride

2-Hydroxybenzylbenzimidazole

Hybendazole

2-(Hydroxyphenylmethyl)benzimidazole

2-(alpha-Hydroxybenzyl)benzimidazole

(1H-benzo[d]imidazol-2-yl)(phenyl)methanol

alpha-Phenyl-2-benzimidazolemethanol

EINECS 200-073-0

NSC 31798

2-(.alpha.-Hydroxybenzyl)benzimidazole

BRN 0198236

alpha-Phenyl-1H-benzimidazole-2-methanol

AI3-24800

NSC-405

1H-Benzimidazole-2-methanol, alpha-phenyl-

5JR6201MX7

NSC-31798

HYBENDAZOLE [WHO-DD]

2-Benzimidazolemethanol, .alpha.-phenyl-

CHEMBL169412

(1H-1,3-benzodiazol-2-yl)(phenyl)methanol

1H-Benzimidazole-2-methanol, .alpha.-phenyl-

DTXSID701018908

5-23-12-00349 (Beilstein Handbook Reference)

(1H-BENZIMIDAZOL-2-YL)(PHENYL)METHANOL

.ALPHA.-PHENYL-1H-BENZIMIDAZOLE-2-METHANOL

Hydrobenzol

UNII-5JR6201MX7

benzimidazol-2-ylphenylmethan-1-ol

MFCD00159953

(1H-Benzoimidazol-2-yl)-phenyl-methanol

1H-1,3-benzodiazol-2-yl(phenyl)methanol

2-BENZIMIDAZOLEMETHANOL, alpha-PHENYL-

Cambridge id 5127020

TimTec1_001558

Oprea1_502237

Oprea1_536656

MLS001207024

SCHEMBL899731

F1216-0101

NSC405

DTXCID201476923

HMS1538G18

HMS2840C21

2-Benzimidazolemethanol, a-phenyl-

ALBB-023544

NSC31798

BDBM50404880

STK215558

(1H-benzimidazol-2-yl)phenylmethanol

AKOS000275595

AKOS016041634

.alpha.-Phenyl-2-benzimidazolemethanol

CCG-116311

1H-Benzimidazol-2-yl(phenyl)methanol #

2-(.alpha.-hydroxybenzyl)-benzimidazole

LS-07422

SMR000524180

NS00041199

EN300-33676

G26030

1H-1,3-BENZIMIDAZOL-2-YL(PHENYL)METHANOL

Q27262460

Z57841692