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Paclitaxel

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Identification
Molecular formula
C47H51NO14
CAS number
33069-62-4
IUPAC name
19-benzyl-6,15-dihydroxy-10,17-dimethyl-16-methylene-2-oxa-20-azatricyclo[12.7.0.01,18]henicosa-4,12-diene-3,21-dione
State
State

At room temperature, paclitaxel is typically in a solid state as a crystalline powder. It needs to be dissolved in suitable solvents for application purposes, particularly in a clinical setting as a chemotherapeutic agent.

Melting point (Celsius)
213.00
Melting point (Kelvin)
486.15
Boiling point (Celsius)
0.00
Boiling point (Kelvin)
0.00
General information
Molecular weight
853.91g/mol
Molar mass
853.9060g/mol
Density
1.6500g/cm3
Appearence

Paclitaxel is typically a white to off-white crystalline powder. It is hydrophobic in nature and usually provided in a solution form for medical use. The compound does not have a distinctive odor and can be visually identified by its powdered form.

Comment on solubility

Solubility of 19-benzyl-6,15-dihydroxy-10,17-dimethyl-16-methylene-2-oxa-20-azatricyclo[12.7.0.01,18]henicosa-4,12-diene-3,21-dione (C47H51NO14)

The solubility of the compound C47H51NO14, known as 19-benzyl-6,15-dihydroxy-10,17-dimethyl-16-methylene-2-oxa-20-azatricyclo[12.7.0.01,18]henicosa-4,12-diene-3,21-dione, is an intriguing aspect of its chemical nature. Understanding its solubility is crucial for various applications and can be influenced by several factors:

  • Polar vs. Nonpolar Solvents: Due to the compound's complex hydroxy groups and multiple functional groups, it may exhibit greater solubility in polar solvents, such as methanol and ethanol, rather than in nonpolar solvents like hexane.
  • Temperature Effects: Like many organic compounds, solubility may increase with temperature. Therefore, heating the solvent may enhance the dissolution process.
  • pH Impact: The presence of hydroxy and nitrogen-containing groups may indicate a dependency on pH levels, with potential changes in solubility in acidic or basic environments.
  • Complex Formation: The ability to form complexes with other molecules could also affect solubility, potentially leading to increased solubility in the presence of specific agents.

In summary, the solubility of 19-benzyl-6,15-dihydroxy-10,17-dimethyl-16-methylene-2-oxa-20-azatricyclo[12.7.0.01,18]henicosa-4,12-diene-3,21-dione is influenced by its unique structural features and the environment in which it is placed. As the saying goes, "Like dissolves like," so understanding the nature of solubility for such complex compounds is essential in predicting their behavior in chemical reactions and formulations.

Interesting facts

Interesting Facts About 19-benzyl-6,15-dihydroxy-10,17-dimethyl-16-methylene-2-oxa-20-azatricyclo[12.7.0.01,18]henicosa-4,12-diene-3,21-dione

This compound is quite a fascinating member of the family of organic molecules, showcasing a unique and intricate structure that brings several intriguing aspects to light:

  • Complexity in Structure: The molecular framework of this compound is notable for its intricate tricyclic arrangement and incorporation of multiple functional groups including hydroxyl, methylene, and nitrogen heterocycles. This complexity can lead to interesting interactions with biological systems.
  • Potential Biological Activity: Compounds with similar structural motifs often show significant biological activities. There is an ever-growing interest in exploring how compounds like this one can aid in drug design, particularly in targeting various diseases.
  • Synthesis Challenges: The synthesis of such a complex organic molecule usually involves multiple steps and requires careful optimization of reaction conditions. This presents a plethora of challenges for chemists, thus making successful synthesis a noteworthy achievement.
  • Applications in Research: The chemical properties and potential applications of this compound could be of great interest in fields such as pharmacology, organic synthesis, and material science. Its unique structure makes it a potential lead compound for new drug discovery.

Quote to Consider

"The beauty of chemistry lies in the intricacies of its structures and the boundless possibilities they present." - Unknown Chemist

In summary, 19-benzyl-6,15-dihydroxy-10,17-dimethyl-16-methylene-2-oxa-20-azatricyclo[12.7.0.01,18]henicosa-4,12-diene-3,21-dione is a testament to the wonders of organic chemistry, embodying both complexity and potential. Its study could unveil a wealth of knowledge contributing to advancements in various scientific domains.

Synonyms
Neuro_000052
SMP1_000088
NCI60_000181