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Cortisone

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Identification
Molecular formula
C21H28O5
CAS number
53-06-5
IUPAC name
17-hydroxy-10,13-dimethyl-1,2,6,7,8,9,11,12,14,15,16,17-dodecahydrocyclopenta[a]phenanthren-3-one
State
State

Cortisone is a solid at room temperature. It is generally handled, stored, and transported in its solid form.

Melting point (Celsius)
220.00
Melting point (Kelvin)
493.15
Boiling point (Celsius)
0.00
Boiling point (Kelvin)
0.00
General information
Molecular weight
360.45g/mol
Molar mass
360.4450g/mol
Density
1.3000g/cm3
Appearence

Cortisone, a corticosteroid, typically appears as a white or near-white crystalline powder. It is odorless and has a slightly bitter taste.

Comment on solubility

Solubility of 17-hydroxy-10,13-dimethyl-1,2,6,7,8,9,11,12,14,15,16,17-dodecahydrocyclopenta[a]phenanthren-3-one

The solubility of the compound 17-hydroxy-10,13-dimethyl-1,2,6,7,8,9,11,12,14,15,16,17-dodecahydrocyclopenta[a]phenanthren-3-one (C21H28O5) can be analyzed through a few key aspects:

  • Polar vs. Nonpolar: As a larger organic molecule, its structure contains both hydrophobic regions (nonpolar) and hydroxyl groups (polar), contributing to its solubility behaviors.
  • Solvent Dependence: This compound is likely to exhibit varying solubility in different solvents. Common solvents to test include:
    • Hydrophobic solvents (e.g., hexane, toluene)
    • Polar solvents (e.g., ethanol, methanol)
  • Temperature Effects: As with many organic compounds, solubility can increase with temperature, promoting the dissolution of solid solutes in liquids.

In summary, while the specific solubility data may need to be experimentally determined, understanding these key factors can greatly aid in predicting how C21H28O5 behaves in various chemical environments. It’s important to consider that solubility is not merely a property of the substance itself but is influenced by external factors such as the solvent type and environmental conditions.

Interesting facts

Interesting Facts About 17-Hydroxy-10,13-dimethyl-1,2,6,7,8,9,11,12,14,15,16,17-dodecahydrocyclopenta[a]phenanthren-3-one

The compound 17-hydroxy-10,13-dimethyl-1,2,6,7,8,9,11,12,14,15,16,17-dodecahydrocyclopenta[a]phenanthren-3-one, commonly referred to in scientific literature as a steroid precursor, showcases fascinating attributes that are vital to both chemistry and biology. Here are several noteworthy points:

  • Steroid Framework: This compound is part of the steroid family, which is well-known for its diverse roles in biological systems, including hormones like testosterone and estrogen.
  • Enzymatic Transformations: Its structure allows it to undergo various enzymatic reactions in the body, making it a crucial intermediate in the biosynthesis of hormones and other important biological molecules.
  • Analytical Importance: Due to its complex structure, it becomes a compelling target for analytical techniques such as mass spectrometry and nuclear magnetic resonance (NMR) spectroscopy to elucidate its properties and behavior.
  • Medical Relevance: Compounds resembling this steroid have potential applications in medicine, especially in treatments involving hormone replacement therapy and anti-inflammatory drugs.
  • Research Interest: Ongoing research includes exploring the potential anti-cancer properties of derivatives of this compound, linking its structure to promising pharmacological benefits.

In summary, 17-hydroxy-10,13-dimethyl-1,2,6,7,8,9,11,12,14,15,16,17-dodecahydrocyclopenta[a]phenanthren-3-one serves as a fascinating example of how complex organic compounds function not only as theoretical subjects of study but also play vital roles in real-world applications stretching from medicine to biochemistry.

Synonyms
17-Hydroxyandrost-4-en-3-one
1221910-14-0
Testosterone-d3
Oreton F
Virormone
(9beta,10alpha)-17beta-Hydroxyandrost-4-en-3-one
Androst-4-en-17.beta.-ol-3-one
17.beta.-Hydroxy-4-androsten-3-one
17.beta.-Hydroxyandrost-4-en-3-one
.DELTA.4-Androsten-17.beta.-ol-3-one
Androst-4-en-3-one, 17.beta.-hydroxy-
17-Hydroxy-(17.beta.)-androst-4-en-3-one
4-ANDROSTEN-17A-OL-3-ONE-2,2,4,6,6-D5
CHEMBL386630
9.beta.,10.alpha.-Testosterone
CPD000109709
Androst-4-en-3-one, 17-hydroxy-, (17.beta.)-
Cambridge id 7215855
Oprea1_852285
MLS000113817
SCHEMBL616350
CHEMBL268313
CHEBI:94444
NSC9700
MUMGGOZAMZWBJJ-UHFFFAOYSA-N
Testosterone- 16,16,17-D3
HMS2268M04
HMS3259H09
17-Hydroxy-10,13-dimethyl-1,2,6,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-cyclopenta[a]phenanthren-3-one
QGA19535
WAA00280
BBL028526
BDBM50025452
NSC523833
STK013235
9-BETA-10-ALPHA-TESTOSTERONE
AKOS000490915
AKOS016037980
NC00634
NSC-523833
17-hydroxy-10,13-dimethyl-1,2,6,7,8,9,11,12,14,15,16,17-dodecahydrocyclopenta[a]phenanthren-3-one
17-hydroxy-10,13-dimethyl-6,7,8,9,10,11,12,13,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-3(2H)-one
SMR000109709
VS-08816
.delta.(4)-Androsten-17.beta.-ol-3-one
EU-0070267
VU0122138-8
WLN: L E5 B666 OV MUTJ A1 E1 FQ
.delta.(sup4)-Androsten-17(.beta.)-ol-3-one
4-Androsten-17?-ol-3-one-2,2,4,6,6-d5
AB00437985-08
17.beta.-Hydroxy-.delta.(sup4)-androsten-3-one
Q27166309
F0452-4293
14-hydroxy-2,15-dimethyltetracyclo[8.7.0.02,7.011,15]heptadec-6-en-5-one
(testosterone)17-Hydroxy-10,13-dimethyl-1,2,6,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-cyclopenta[a]phenanthren-3-one
1-hydroxy-9a,11a-dimethyl-1H,2H,3H,3aH,3bH,4H,5H,7H,8H,9H,9aH,9bH,10H,11H,11aH-cyclopenta[a]phenanthren-7-one
17-hydroxy-10,13-dimethyl-1,2,6,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-3H-cyclopenta[a]phenanthren-3-one
17-Hydroxy-10,13-dimethyl-1,2,6,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-cyclopenta[a]phenanthren-3-one (Testosterone)
17-Hydroxy-10,13-dimethyl-1,2,6,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-cyclopenta[a]phenanthren-3-one(testosterone)