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Ethinylestradiol

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Identification
Molecular formula
C20H24O2
CAS number
57-63-6
IUPAC name
17-ethynyl-17-hydroxy-13-methyl-1,2,4,6,7,8,9,11,12,14,15,16-dodecahydrocyclopenta[a]phenanthren-3-one
State
State

At room temperature, Ethinylestradiol is typically in a solid state.

Melting point (Celsius)
183.00
Melting point (Kelvin)
456.15
Boiling point (Celsius)
474.30
Boiling point (Kelvin)
747.45
General information
Molecular weight
296.41g/mol
Molar mass
296.4070g/mol
Density
1.1654g/cm3
Appearence

Ethinylestradiol typically appears as a white to creamy white, odorless, crystalline powder. It is often found in pharmaceutical formulations and exhibits poor solubility in water but is soluble in alcohol, chloroform, and benzene.

Comment on solubility

Solubility of 17-Ethynyl-17-hydroxy-13-methyl-1,2,4,6,7,8,9,11,12,14,15,16-dodecahydrocyclopenta[a]phenanthren-3-one (C20H24O2)

The solubility of 17-ethynyl-17-hydroxy-13-methyl-1,2,4,6,7,8,9,11,12,14,15,16-dodecahydrocyclopenta[a]phenanthren-3-one in various solvents is a critical aspect to consider, especially in pharmaceutical applications. This compound exhibits a certain degree of solubility properties which can be summarized as follows:

  • Polar Solvents: The presence of hydroxyl (-OH) groups may enhance the solubility of this compound in polar solvents such as water and ethanol, but it could still have *limited solubility* due to its hydrophobic structural components.
  • Non-Polar Solvents: The hydrocarbon-like structure promotes solubility in non-polar solvents like hexane or chloroform. In such cases, the solubility is likely to be *more favorable*.
  • Mixed Solvent Systems: The compound may exhibit variable solubility in mixed solvent systems where polar and non-polar characteristics can interact, potentially resulting in *enhanced solubility compared to pure solvents*.

It's important to note that the solubility can be influenced by temperature, concentration, and specific conditions of the solvent environment. Understanding these factors aids in optimizing its use in various chemical processes.

Interesting facts

Interesting Facts about 17-Ethynyl-17-hydroxy-13-methyl-1,2,4,6,7,8,9,11,12,14,15,16-dodecahydrocyclopenta[a]phenanthren-3-one

17-Ethynyl-17-hydroxy-13-methyl-1,2,4,6,7,8,9,11,12,14,15,16-dodecahydrocyclopenta[a]phenanthren-3-one is a fascinating compound that belongs to the class of synthetic steroids. Here are some captivating aspects of this compound:

  • Synthetic Steroid: This compound is primarily known for its use as a synthetic steroid. Synthetic steroids are typically designed to mimic the effects of natural hormones in the body, particularly testosterone.
  • Hormonal Activity: Due to its structural similarities to natural hormones, it can possess activities that affect various physiological processes, including metabolism, immune function, and muscle growth.
  • Important Research Tool: This particular steroid compound is often used in scientific studies to better understand the mechanisms of steroid hormones and their impacts on various biological systems.
  • Medical Applications: Researchers are investigating its potential therapeutic applications, which may include treating hormonal imbalances or certain types of cancer, highlighting its importance in pharmacology.
  • Chemical Complexity: The intricate structure of this compound, characterized by its multiple ring systems and functional groups, presents a rich field for study in organic synthesis and drug design.

Overall, 17-ethynyl-17-hydroxy-13-methyl-1,2,4,6,7,8,9,11,12,14,15,16-dodecahydrocyclopenta[a]phenanthren-3-one is not just a compound of interest in terms of its physical and chemical properties, but also a significant participant in the ongoing dialogue around hormonal therapies and synthetic biology.

Synonyms
Infecundin
8-Isonorethynodrel
13577-86-1
MLS002638434
19-Norpregn-5(10)-en-20-yn-3-one,17-hydroxy-, (17a)-
17-Ethynyl-17-hydroxyestr-5(10)-en-3-one
17-ethynyl-17-hydroxy-13-methyl-1,2,4,6,7,8,9,11,12,14,15,16-dodecahydrocyclopenta[a]phenanthren-3-one
17.alpha.-Ethinyl-5,10-estrenolone
17.alpha.-Ethinyl-estra(5,10)eneolone
17.alpha.-Ethynyl-5(10)-estren-17-ol-3-one
17.alpha.-Ethynyl-17-hydroxy-5(10)-estren-3-one
17.alpha.-Ethynylestr-5(10)-en-17.beta.-ol-3-one
17.alpha.-Ethynyl-estr-5(10)-en-3-on-17.beta.-ol
Estr-5(10)-en-3-one, 17.alpha.-ethynyl-17-hydroxy-
17.alpha.-Ethynyl-17.beta.-hydroxyestr-5(10)-en-3-one
17-Hydroxy(17.alpha.)-19-norpregn-5(10)-en-20-yn-3-one
17.alpha.-Ethynyl-19-nor-5(10)-androsten-17.beta.-ol-3-one
19-nor-17.alpha.-Pregn-5(10)-en-20-yn-3-one, 17-hydroxy-
17.alpha.-Ethinyl-.delta.(sup)-5,10-19-nortestosterone
Oprea1_318061
17-Hydroxy-19-nor-17.alpha.-pregn-5(10)-en-20-yn-3-one
CHEMBL1719162
HMS3089L12
BBL033851
NSC109510
STL372919
AKOS025247999
NSC-109510
SMR001547914
VS-12314
WLN: L E5 B666 OV MUTJ E1 F1UU1 QQ
19-Norpregn-5(10)-en-20-yn-3-one, (17.alpha.)-
17.alpha.-Ethynyl-17.beta.-hydroxyester-5(10)-en-3-one
17.alpha.-Ethinyl-17.beta.-hydroxy-.delta.(sup 5(10))-estren-3-one
17.alpha.-Ethynyl-17.beta.-hydroxy-.delta.(sup 5(10))-estren-3-one
17.alpha.-Ethynyl-17.beta.-hydroxy-3-oxo-.delta.(sup 5(10))-estrene
1-ethynyl-1-hydroxy-11a-methyl-1H,2H,3H,3aH,3bH,4H,5H,6H,7H,8H,9H,9bH,10H,11H,11aH-cyclopenta[a]phenanthren-7-one