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Ethinylestradiol

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Identification
Molecular formula
C20H24O2
CAS number
57-63-6
IUPAC name
17-ethynyl-13-methyl-7,8,9,11,12,14,15,16-octahydro-6H-cyclopenta[a]phenanthrene-3,17-diol
State
State

In its standard form, ethinylestradiol is a solid. It is often supplied in a crystalline powder form, making it a solid under ambient temperature and pressure conditions.

Melting point (Celsius)
182.00
Melting point (Kelvin)
455.20
Boiling point (Celsius)
536.90
Boiling point (Kelvin)
810.00
General information
Molecular weight
296.40g/mol
Molar mass
296.4030g/mol
Density
1.2300g/cm3
Appearence

Ethinylestradiol typically appears as a white to creamy white crystalline powder. It is odorless and exhibits polymorphism, that is, the ability to exist in multiple crystalline forms. The fine powder form can make it difficult to handle due to its tendency to become airborne easily.

Comment on solubility

Solubility of 17-ethynyl-13-methyl-7,8,9,11,12,14,15,16-octahydro-6H-cyclopenta[a]phenanthrene-3,17-diol (C20H24O2)

The solubility of this compound is an interesting aspect due to its unique structural configuration and functional groups. Understanding its solubility can provide insights into its potential applications and behavior in various environments. Here are some key points regarding its solubility:

  • Polarity: The presence of hydroxyl (-OH) groups generally increases solubility in polar solvents, such as water, while hydrophobic hydrocarbon structures may limit this solubility.
  • Solvent Compatibility: This compound may exhibit greater solubility in organic solvents like ethanol, methanol, and dichloromethane, given its hydrophobic carbon framework.
  • Temperature Influence: Increased temperature typically enhances solubility for many compounds; however, specific behavior can vary based on interactions between solute and solvent.
  • Concentration Effects: The solubility may depend on concentration limits, with saturation thresholds leading to varied solubility profiles under different conditions.

In conclusion, while compounds featuring bulky and hydrophobic structures like C20H24O2 can present challenges for solubility in water, their behavior in organic solvents and response to varying conditions can lead to valuable applications in pharmacology and materials science. As each compound behaves distinctly, experimental assessment is crucial for accurate solubility characterization.

Interesting facts

Interesting Facts About 17-ethynyl-13-methyl-7,8,9,11,12,14,15,16-octahydro-6H-cyclopenta[a]phenanthrene-3,17-diol

17-ethynyl-13-methyl-7,8,9,11,12,14,15,16-octahydro-6H-cyclopenta[a]phenanthrene-3,17-diol is a synthetic compound that is gaining attention in various fields of study, particularly in medicinal chemistry and pharmacology. Here are some interesting facts about this compound:

  • Synthesis and Structure: This compound features a complex molecular structure that includes a cyclopenta[a]phenanthrene backbone, which is significant in the development of steroid-like molecules.
  • Medical Applications: Research has indicated that compounds in this class may exhibit activity against certain cancers and may also play a role in hormone regulation.
  • Functional Groups: The presence of multiple hydroxyl (–OH) groups in its structure may contribute to its biological activity, influencing interactions with biological receptors.
  • Ethynyl Group: The ethynyl group (–C≡CH) in its structure often enhances the lipophilicity and biological activity of the molecule, which can be crucial in drug design.
  • Potential Variants: The synthesis of derivatives and analogs of this compound may yield new compounds with different pharmacological properties, making it an exciting area for further research.

In scientific literature, compounds like 17-ethynyl-13-methyl-7,8,9,11,12,14,15,16-octahydro-6H-cyclopenta[a]phenanthrene-3,17-diol often serve as pivotal molecules for exploring new therapeutic pathways and understanding complex biological mechanisms. As researchers continue to study such compounds, they may uncover novel applications that could revolutionize treatment options in medicine.

Synonyms
17-Ethynylestra-1(10),2,4-triene-3,17-diol
17-Ethynyl-3,17-dihydroxy-1,3,5-oestratriene
NCIOpen2_007218
Oprea1_775480
SCHEMBL7602883
CHEBI:125402
ALBB-025012
NSC104490
STL451029
AKOS001606809
AKOS017258736
NSC-104490
NCGC00249018-01
NCGC00249018-02
17-ethynyl-13-methyl-7,8,9,11,12,14,15,16-octahydro-6H-cyclopenta[a]phenanthrene-3,17-diol
AS-13834
EU-0001730
EN300-297603
BRD-A43286952-001-01-7
estra-1(10),2,4-triene-3,17-diol, 17-ethynyl-
Q27215967
19-Nor-1,3,5(10),17a-pregnatrien-20-yne-3,17-diol
1-ethynyl-11a-methyl-1H,2H,3H,3aH,3bH,4H,5H,9bH,10H,11H,11aH-cyclopenta[a]phenanthrene-1,7-diol
2649017-02-5