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Atracurium besylate

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Identification
Molecular formula
C65H82N2O18
CAS number
64228-81-5
IUPAC name
[17-acetoxy-10,13-dimethyl-2,16-bis(1-methylpiperidin-1-ium-1-yl)-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-3-yl] acetate
State
State

Solid at room temperature.

Melting point (Celsius)
167.00
Melting point (Kelvin)
440.15
Boiling point (Celsius)
250.00
Boiling point (Kelvin)
523.15
General information
Molecular weight
1243.53g/mol
Molar mass
1 243.5330g/mol
Density
1.3430g/cm3
Appearence

A white to off-white crystalline powder.

Comment on solubility

Solubility of 17-acetoxy-10,13-dimethyl-2,16-bis(1-methylpiperidin-1-ium-1-yl)-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-3-yl acetate

The solubility of the compound with the formula C65H82N2O18 can be characterized through several key factors:

  • Polarity: This compound contains multiple functional groups, including esters and amines, which influence its solubility in various solvents. The presence of these polar groups suggests higher solubility in polar solvents such as water and alcohols.
  • Molecular Size: The large molecular structure, indicated by its lengthy carbon chain, may result in lower solubility in non-polar solvents due to steric hindrance and insufficient interaction with the solvent molecules.
  • Ionic Nature: The presence of quaternary ammonium groups (from the methylpiperidine units) enhances the solubility in ionic and aqueous environments, whereby the compound may interact favorably with water molecules.
  • Conditions: Solubility can also be influenced by temperature and pH; for instance, increased temperature may improve solubility. Conversely, changes in pH may affect the ionization of the amine groups.

Overall, the solubility of this unique compound is likely to exhibit notable variability depending on the solvent environment. It may demonstrate significant solubility in polar solvents while potentially being less soluble in purely non-polar media. To understand the detailed solubility characteristics, empirical studies would provide the most accurate insights.

Interesting facts

Interesting Facts about 17-Acetoxy-10,13-dimethyl-2,16-bis(1-methylpiperidin-1-ium-1-yl)-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-3-yl Acetate

This fascinating compound belongs to the class of organic molecules known as alkaloids, which are known for their diverse range of biological activities and potential therapeutic applications. Here are some intriguing facts about this specific alkaloid:

  • Complex Structure: With a molecular structure that includes multiple rings and functional groups, this compound demonstrates the intricate nature of organic chemistry. Its composition highlights the importance of stereochemistry and molecular conformation in determining its biological activity.
  • Potential Pharmacological Effects: Many compounds similar to this one have been investigated for their effects as analgesics, antidepressants, and anti-inflammatory agents. Researchers are continuously exploring how specific molecular modifications can enhance their efficacy and reduce side effects.
  • Application in Drug Design: The presence of the piperidine moiety in this compound suggests potential applications in drug design, especially in developing novel therapeutic agents targeting the nervous system. Piperidine derivatives have shown promising results in numerous studies, enhancing the understanding of neuropharmacology.
  • Research and Development: Synthetic routes to create such complex structures often involve multi-step synthesis and careful selection of reagents, underscoring the challenges chemists face in drug discovery. This also emphasizes the need for innovative strategies in organic synthesis.
  • Interdisciplinary Impact: The study of this compound intersects various fields, including medicinal chemistry, pharmacology, and material science, showcasing the interdisciplinary nature of modern chemical research.

As chemists and researchers delve deeper into the properties and potential applications of compounds like this, the enduring quest for innovative therapies continues to evolve, fueled by the complexities hidden within their molecular structures. The journey from laboratory to potential therapeutic use exemplifies the beauty and challenges of chemistry.

Synonyms
BDBM86425
CAS_27350
NSC_27350