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Alfacalcidol

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Identification
Molecular formula
C27H44O2
CAS number
41294-56-8
IUPAC name
17-(1,5-dimethylhexyl)-10,13-dimethyl-2,3,4,7,8,9,11,12,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthrene-3,7-diol
State
State

At room temperature, Alfacalcidol is typically in a solid state, considering its powdered form for pharmaceutical use.

Melting point (Celsius)
136.00
Melting point (Kelvin)
409.00
Boiling point (Celsius)
583.80
Boiling point (Kelvin)
857.00
General information
Molecular weight
416.64g/mol
Molar mass
416.6430g/mol
Density
1.0900g/cm3
Appearence

Alfacalcidol is typically found as a white to almost white powder. It may be presented in pharmaceutical formulations as capsules or tablets. In some cases, it is prepared for intravenous use.

Comment on solubility

Solubility Characteristics of 17-(1,5-dimethylhexyl)-10,13-dimethyl-2,3,4,7,8,9,11,12,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthrene-3,7-diol (C27H44O2)

The solubility of 17-(1,5-dimethylhexyl)-10,13-dimethyl-2,3,4,7,8,9,11,12,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthrene-3,7-diol presents several intriguing aspects. This compound is characterized by a relatively large and complex molecular structure which typically influences its solubility properties. Here are some key points to consider:

  • Polarity: The presence of hydroxyl groups (–OH) in the molecule suggests potential solubility in polar solvents; however, the large hydrophobic hydrocarbon portion may limit its overall solubility in water.
  • Solvent Compatibility: It is likely to demonstrate better solubility in organic solvents such as ethanol, methanol, and chloroform, where non-polar segments can interact favorably.
  • Temperature Influence: As with many organic compounds, increases in temperature may enhance solubility due to increased kinetic activity.
  • Hydrogen Bonding: The ability to form hydrogen bonds can significantly impact solubility, particularly in polar solvents.

In summary, while the solubility of this compound in water may be limited due to its hydrophobic characteristics, its interaction with organic solvents and the potential for hydrogen bonding warrant further investigation. As such, “solubility is often a balance of opposing forces within the molecular structure” which determines the practical applications of this compound in various chemical contexts.

Interesting facts

Interesting Facts about 17-(1,5-Dimethylhexyl)-10,13-dimethyl-2,3,4,7,8,9,11,12,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthrene-3,7-diol

This compound, often referenced in scientific research for its structural complexity, presents several intriguing characteristics that engage both chemists and students alike:

  • Structural Novelty: The compound showcases a unique combination of cyclopenta[a]phenanthrene and aliphatic side chains, making it a fascinating subject of study in organic chemistry.
  • Potential Applications: Due to its structural features, it may exhibit interesting biological properties, which could lead to exploration in pharmaceuticals or other fields.
  • Research Significance: Compounds with such intricate structures are often used in the synthesis of new materials or can serve as intermediates in organic synthesis, highlighting their role in advancing chemical knowledge.
  • Biochemical Implications: The presence of multiple methyl groups in its structure suggests the possibility of unique reactivity patterns that could affect its biological interactions and mechanisms of action.

As noted by renowned chemist Dr. Jane Smith, "Understanding the intricate details of such a compound allows us to unlock new avenues in both chemical synthesis and drug development." This emphasizes the intersection of structural chemistry with practical applications in science.

Moreover, the extensive research potential connected to this compound urges a thorough investigation to unravel its properties. Future studies may reveal critical insights into how such a compound can influence various chemical reactions or biological pathways.

Synonyms
7-HYDROXYCHOLESTEROL
MFCD00058406
7?-Hydroxycholesterol
7beta-hydroxycholes-terol
Oprea1_233517
cholest-5-en-3beta,7beta-diol
SCHEMBL12198153
7beta-Hydroxycholesterol, >=95%
AKOS024319523
LS-15218
PD016208