Skip to main content

Calcitriol

ADVERTISEMENT
Identification
Molecular formula
C27H44O3
CAS number
32222-06-3
IUPAC name
17-(1,2-dihydroxy-1,5-dimethyl-hexyl)-2,3,5,11,14-pentahydroxy-10,13-dimethyl-1,2,3,4,9,11,12,15,16,17-decahydrocyclopenta[a]phenanthren-6-one
State
State
Solid at room temperature.
Melting point (Celsius)
118.00
Melting point (Kelvin)
391.15
Boiling point (Celsius)
745.00
Boiling point (Kelvin)
1 018.15
General information
Molecular weight
416.65g/mol
Molar mass
416.6470g/mol
Density
1.2500g/cm3
Appearence

Calcitriol is a white, crystalline substance. It is sparingly soluble in water and freely soluble in organic solvents like ethanol and chloroform, making it ideal for pharmaceutical formulations.

Comment on solubility

Solubility of 17-(1,2-dihydroxy-1,5-dimethyl-hexyl)-2,3,5,11,14-pentahydroxy-10,13-dimethyl-1,2,3,4,9,11,12,15,16,17-decahydrocyclopenta[a]phenanthren-6-one

The solubility of the compound with the formula C27H44O3 is influenced by several factors due to its complex structural features. Here's a breakdown of important considerations regarding its solubility:

  • Polarity: The presence of multiple hydroxyl (–OH) groups suggests that the compound has polar characteristics, which generally enhance its solubility in polar solvents like water.
  • Hydrophobic Effects: Conversely, the large hydrophobic (fatty) regions associated with the hydrocarbon chain can reduce solubility in polar environments. This creates a duality in solubility profiles depending on the environment.
  • Solvent Selection: The compound is more likely to dissolve in organic solvents such as ethanol, methanol, or acetone rather than in water due to its high molecular weight and hydrophobic sections.

In conclusion, the solubility of this compound can be summarized as:

  1. Moderately soluble in polar solvents.
  2. More soluble in organic solvents.
  3. Solubility may vary significantly depending on the presence of other solutes or the solvent conditions.

As stated in the realm of chemistry, "like dissolves like." Thus, understanding the specific solvent characteristics will play a crucial role in utilizing this compound effectively in various applications.

Interesting facts

Interesting Facts about 17-(1,2-dihydroxy-1,5-dimethyl-hexyl)-2,3,5,11,14-pentahydroxy-10,13-dimethyl-1,2,3,4,9,11,12,15,16,17-decahydrocyclopenta[a]phenanthren-6-one

This compound represents a complex molecular structure, displaying unique characteristics that contribute to its significance in the realm of chemistry. Here are some intriguing facts about this remarkable compound:

  • Synthetic Pathway: The synthesis of this compound can involve multiple steps, showcasing the intricate nature of organic synthesis. Researchers often explore different methods to optimize yield and purity.
  • Natural Analogues: This compound bears resemblance to certain natural compounds found in nature, particularly those linked to hormonal activity. Its structure suggests potential interactions with biological systems.
  • Potential Applications: Due to its unique structural features, this compound may have implications in medicinal chemistry, particularly in drug design targeting specific biological pathways.
  • Research Interest: The detailed study of this compound could lead to insights in fields such as pharmacology and biochemistry, especially when exploring the mechanisms of action of similar compounds.
  • Complexity in Analysis: Analyzing this compound's properties involves advanced techniques such as NMR, mass spectrometry, and chromatography, which provide critical data about its functional groups and conformational flexibility.

As scientists and researchers delve deeper into the characterization and functionality of 17-(1,2-dihydroxy-1,5-dimethyl-hexyl)-2,3,5,11,14-pentahydroxy-10,13-dimethyl-1,2,3,4,9,11,12,15,16,17-decahydrocyclopenta[a]phenanthren-6-one, they continue to uncover the complexities and potential of such chemical compounds, contributing to the advancement of fields like pharmaceuticals and therapeutic interventions.

Synonyms
DB-049331
G85430