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Codeine methylsulfate

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Identification
Molecular formula
C20H26N1O5.HSO4
CAS number
125-31-5
IUPAC name
16,17-dimethoxy-5,7-dioxa-13-azoniapentacyclo[11.8.0.02,10.04,8.015,20]henicosa-1(13),2,4(8),9,14,16,18,20-octaene;sulfate
State
State

This compound is a solid at room temperature, often appearing as a fine, white crystalline powder. It is stable under normal conditions and can be handled in typical laboratory settings without special temperature requirements.

Melting point (Celsius)
150.00
Melting point (Kelvin)
423.15
Boiling point (Celsius)
270.00
Boiling point (Kelvin)
543.15
General information
Molecular weight
397.48g/mol
Molar mass
397.4800g/mol
Density
1.3400g/cm3
Appearence

The compound appears as a white crystalline solid. It is commonly found in powder form and is highly soluble in water, resulting in clear to slightly cloudy solutions. The crystalline structure is typically fine and resembles other sulfate compounds.

Comment on solubility

Solubility of 16,17-dimethoxy-5,7-dioxa-13-azoniapentacyclo[11.8.0.02,10.04,8.015,20]henicosa-1(13),2,4(8),9,14,16,18,20-octaene; sulfate

The solubility of 16,17-dimethoxy-5,7-dioxa-13-azoniapentacyclo[11.8.0.02,10.04,8.015,20]henicosa-1(13),2,4(8),9,14,16,18,20-octaene; sulfate in various solvents is predominantly dictated by its chemical structure and the presence of functional groups. Understanding its solubility behavior can be summarized as follows:

  • Water Solubility: Due to the presence of sulfate groups and nitrogen atoms, this compound may exhibit some degree of solubility in water, as polar groups tend to interact favorably with water molecules.
  • Solvent Compatibility: The solubility is likely to vary significantly in organic solvents. For instance, solvents such as methanol and ethanol may dissolve this compound more effectively compared to non-polar solvents like hexane.
  • Temperature Dependency: Solubility can also be influenced by temperature; typically, higher temperatures increase solubility for many compounds.
  • pH Effects: The solubility might change with varying pH levels, especially considering the ionic characteristics of the sulfate group, which could enhance solubility in acidic conditions.

In conclusion, while this compound may be reasonably soluble in polar solvents due to its functional groups, specific solubility assessments through experimental data will be essential to ascertain its complete solubility profile. As a general observation, compounds with complex structures like this tend to exhibit variable solubility, necessitating careful evaluation under varied conditions.

Interesting facts

Interesting Facts about 16,17-Dimethoxy-5,7-dioxa-13-azoniapentacyclo[11.8.0.02,10.04,8.015,20]henicosa-1(13),2,4(8),9,14,16,18,20-octaene; sulfate

This fascinating chemical compound is notable for its unique structural framework, which represents a significant area of interest in medicinal chemistry and materials science. Its intricate configuration comprises multiple fused ring systems, making it an exemplary subject for studies in stereochemistry and molecular interactions.

Key Highlights

  • Structural Complexity: The compound's pentacyclic structure offers rich pathways for reactivity and functionalization.
  • Potential Biological Activity: Compounds with azonia functionality often exhibit intriguing biological properties, which could be explored in pharmacological applications.
  • Applications in Material Science: Its unique geometry may lead to interesting properties, paving the way for innovations in organic electronics and nanotechnology.
  • Sulfate Ion Interaction: The presence of the sulfate ion can enhance solubility and bioavailability, making it a point of study for drug formulation.

Given the complex nature of its molecular design, the compound serves as a versatile platform for a variety of research endeavors. As scientists continue to explore its properties, it holds promise for new insights into both fundamental chemistry and applied sciences. As one chemist notably said, "The beauty of chemistry lies not only in the simplicity of the compounds but also in the intricate dance of complexity that nature provides."

Overall, 16,17-Dimethoxy-5,7-dioxa-13-azoniapentacyclo[11.8.0.02,10.04,8.015,20]henicosa-1(13),2,4(8),9,14,16,18,20-octaene; sulfate embodies the fascinating intersection of chemistry, biology, and material science, making it a compelling subject for ongoing research.

Synonyms
Berberine sulphate
316-41-6
BERBERINE SULFATE
Berberine sulfate trihydrate
Berberin sulfate
Neutral berberine sulfate
6190-33-6
Berberal
Berberine sulfate (2:1)
Berberine sulfate hydrate
AI3-61947
69352-97-2
Berberine.sulfate.3H20
FST3E667FF
Berberine sulfate anhydrous
Erben
Benzo(g)-1,3-benzodioxolo(5,6-a)quinolizinium, 5,6-dihydro-9,10-dimethoxy-, sulfate (2:1)
5,6-Dihydro-9,10-dimethoxybenzo(g)-1,3-benzodioxolo(5,6-a)quinolizinium sulfate
Berberine sulfate (VAN)
Benzo[g]-1,3-benzodioxolo[5,6-a]quinolizinium,5,6-dihydro-9,10-dimethoxy-, sulfate (2:1), trihydrate
NSC-5355
HSDB 2170
NSC 5355
EINECS 206-258-2
UNII-FST3E667FF
Berberinsulfat
Benzo[g]-1,3-benzodioxolo[5,6-a]quinolizinium, 5,6-dihydro-9,10-dimethoxy-, sulfate (2:1); Berberine, sulfate (7CI); Berbinium, 7,8,13,13a-tetradehydro-9,10-dimethoxy-2,3-(methylenedioxy)-, sulfate (2:1) (8CI); Berberine sulfate (2:1); Neutral berberine sulfate
Benzo(g)-1,3-benzodioxolo(5,6-a)quinolizinium, 5,6-dihydr0-9,10-dimethoxy-, sulfate (2:1)
Berbinium, 7,8,13,13a-tetradehydro-9,10-dimethoxy-2,3-(methylenedioxy)-, sulfate (2:1)
SCHEMBL94112
BERBERINE SULFATE [HSDB]
DTXSID70977452
OJVABJMSSDUECT-UHFFFAOYSA-L
BERBERINE SULFATE [WHO-DD]
GAA19033
AKOS024319280
FB61647
FU70620
16,17-dimethoxy-5,7-dioxa-13-azoniapentacyclo[11.8.0.02,10.04,8.015,20]henicosa-1(13),2,4(8),9,14,16,18,20-octaene;sulfate
BS-16855
B0451
NS00079278
D88653
Q27278174
5,6-DIHYDRO-9,10-DIMETHOXYBENZO(G)-1,3-BENZODIOXOLO(5,6-A)QUINOLIZINIUM SULPHATE
9,10-Dimethoxy-5,6-dihydro-[1,3]dioxolo[4,5-g]isoquinolino[3,2-a]isoquinolin-7-ium sulfate(2:1)
9,10-Dimethoxy-5,6-dihydro-[1,3]dioxolo[4,5-g]isoquinolino[3,2-a]isoquinolin-7-iumsulfate(2:1)
bis(16,17-dimethoxy-5,7-dioxa-13??-azapentacyclo[11.8.0.0(2),(1)?.0?,?.0(1)?,(2)?]henicosa-1(13),2(10),3,8,14,16,18,20-octaen-13-ylium) sulfate
Bis(9,10-dimethoxy-5,6-dihydro-2H-[1,3]dioxolo[4,5-g]isoquinolino[3,2-a]isoquinolin-7-ium) sulfate