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15-Hydroxyicosatetraenoic acid

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Identification
Molecular formula
C20H32O3
CAS number
67701-06-4
IUPAC name
15-hydroxyicosa-8,11,13-trienoic acid
State
State

At room temperature, this compound is typically a liquid, owing to its unsaturated structure which lowers its melting point compared to saturated fatty acids.

Melting point (Celsius)
-8.00
Melting point (Kelvin)
265.15
Boiling point (Celsius)
214.00
Boiling point (Kelvin)
487.15
General information
Molecular weight
318.47g/mol
Molar mass
318.4690g/mol
Density
0.9270g/cm3
Appearence

15-Hydroxyicosa-8,11,13-trienoic acid is an oily, pale yellow liquid with a slightly viscous texture. It is usually colorless to light yellow.

Comment on solubility

Solubility of 15-Hydroxyicosa-8,11,13-trienoic Acid

15-hydroxyicosa-8,11,13-trienoic acid (C20H32O3) displays unique solubility characteristics that are influenced by its molecular structure. This compound, a type of fatty acid, exhibits varying degrees of solubility in different solvents due to the presence of its long hydrocarbon chain and hydroxyl group. Here are some key points to consider:

  • Polar Solvent Interaction: The hydroxyl (-OH) group contributes to polar interactions, making 15-hydroxyicosa-8,11,13-trienoic acid more soluble in polar solvents such as methanol and ethanol.
  • Non-polar Solvent Interaction: Conversely, its long hydrocarbon chain enhances solubility in non-polar solvents like hexane and chloroform.
  • Aqueous Solubility: This compound is sparingly soluble in water due to its mostly hydrophobic character, which reduces its ability to interact with water molecules effectively.
  • Temperature Effects: As with many organic compounds, the solubility of 15-hydroxyicosa-8,11,13-trienoic acid can also increase with rising temperatures.

In conclusion, the solubility of 15-hydroxyicosa-8,11,13-trienoic acid is a complex interplay of its structural features and the solvent environment. Understanding these solubility patterns is crucial for applications in biochemical research and formulations in pharmaceuticals.

Interesting facts

Interesting Facts about 15-Hydroxyicosa-8,11,13-trienoic Acid

15-Hydroxyicosa-8,11,13-trienoic acid, often abbreviated as 15-Hydroxy-icosatrienoic acid, is a fascinating compound notable for its role in biochemical processes. Here are some engaging facts about this intriguing fatty acid:

  • Endocannabinoid System: This compound is a part of the endocannabinoid system; it has been suggested to have various effects on both central nervous system functions and peripheral processes.
  • Biological Significance: 15-Hydroxyicosa-8,11,13-trienoic acid is generated from the metabolism of the polyunsaturated fatty acid arachidonic acid via the action of lipoxygenase enzymes. Its presence is significant in the regulation of inflammatory responses.
  • Potential Therapeutic Uses: Research has indicated that compounds like 15-Hydroxyicosa-8,11,13-trienoic acid may have therapeutic potential in treating diseases related to inflammation, pain, and other metabolic disorders.
  • Structure-Activity Relationship: Understanding the structural characteristics of this compound is crucial as it helps in the development of analogs that might enhance its biological efficacy or reduce potential side effects.
  • Natural Sources: This compound can be derived from various natural sources, particularly in processes involving the metabolism of dietary fatty acids. Its occurrence in certain tissues emphasizes the importance of dietary fats in health and disease.

In summary, 15-Hydroxyicosa-8,11,13-trienoic acid is much more than just a chemical; it's a key player in the intricate web of biological systems, potentially offering insights into new therapeutic avenues. As stated by researchers, "Understanding the functionality of such compounds may revolutionize our approaches to health and disease management."

Continued research into this compound can unveil new pathways for understanding metabolic functions and may pave the way for innovations in drug design and development.

Synonyms
15(S)-HETRE
15-hydroxyicosa-8,11,13-trienoic acid
92693-02-2
SDA69302
PD050382