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15-Hydroxyicosa-11,13-dienoic acid

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Identification
Molecular formula
C20H36O3
CAS number
19780-11-1
IUPAC name
15-hydroxyicosa-11,13-dienoic acid
State
State

At room temperature, it is typically a liquid.

Melting point (Celsius)
15.00
Melting point (Kelvin)
288.15
Boiling point (Celsius)
370.00
Boiling point (Kelvin)
643.15
General information
Molecular weight
312.49g/mol
Molar mass
312.4910g/mol
Density
0.8000g/cm3
Appearence

It usually appears as a colorless oil or a liquid with a characteristic odor. It can be somewhat viscous in nature.

Comment on solubility

Solubility of 15-hydroxyicosa-11,13-dienoic acid

The solubility of 15-hydroxyicosa-11,13-dienoic acid (C20H36O3) can be quite intriguing, especially when considering its structural characteristics. This compound is a type of polyunsaturated fatty acid, which often influences its solubility behavior in various solvents.

Key Factors Affecting Solubility:

  • Polar vs. Nonpolar Solvents: Due to the presence of hydroxyl (-OH) groups, this acid shows better solubility in polar solvents such as water and alcohols.
  • Hydrophobicity: The long hydrocarbon chain contributes to hydrophobic interactions, reducing solubility in water while increasing it in organic solvents.
  • Temperature: Like many organic acids, solubility may increase with temperature, enhancing the dissolution process.

In summary, 15-hydroxyicosa-11,13-dienoic acid exhibits variable solubility depending on the nature of the solvent. It tends to dissolve well in polar environments, while more organic solvents provide a fitting medium for its hydrophobic characteristics. As stated, "Like dissolves like," emphasizing the significance of polarity in solubility phenomena.

Interesting facts

Facts about 15-Hydroxyicosa-11,13-dienoic Acid

15-Hydroxyicosa-11,13-dienoic acid, often abbreviated as 15-HETE, is an intriguing compound that plays a significant role in the field of biochemistry and pharmacology. This fatty acid is primarily known for its involvement in various physiological processes and has garnered attention due to its:

  • Biological Significance: As a product of arachidonic acid metabolism, 15-HETE is a member of the eicosanoid family, which are bioactive lipids that influence inflammation and immune responses.
  • Role in Hemostasis: Research has indicated that 15-HETE participates in the regulation of blood clotting, making it an important compound for understanding cardiovascular health.
  • Potential Therapeutic Applications: Studies are ongoing to explore 15-HETE's potential in treating conditions such as cancer and vascular diseases, given its influence on cell signaling pathways.

Interestingly, researchers often highlight the dual nature of 15-HETE. On one hand, it is known to exhibit pro-inflammatory properties, thus playing a role in the body’s response to injury. On the other hand, it can also have anti-inflammatory effects, indicating a complex regulatory role in inflammatory pathways.

Future Perspectives

The ongoing investigation into 15-HETE opens up a multitude of questions regarding its full range of physiological effects. Scientists are increasingly focused on:

  • Mechanistic pathways: Understanding how 15-HETE interacts at a cellular level.
  • Clinical relevance: Evaluating its potential as a biomarker for certain diseases.
  • Formulation possibilities: Developing drugs that could modify the levels of 15-HETE to therapeutic advantage.

In essence, 15-hydroxyicosa-11,13-dienoic acid stands as a pivotal compound at the intersection of biochemistry and medicine, representing both the complexity of human health and the potential for innovative therapeutic approaches.

Synonyms
(+/-)15-HEDE
77159-57-0
15(S)-HEDE
92693-04-4
15-hydroxy-11(Z),13(E)-eicosadienoic acid
CDA15957