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Camptothecin

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Identification
Molecular formula
C20H16N2O5
CAS number
7689-03-4
IUPAC name
(13-hydroxy-8,14,19-trimethoxy-4,10,12,16-tetramethyl-3,20,22-trioxo-2-azabicyclo[16.3.1]docosa-1(21),4,6,10,18-pentaen-9-yl) carbamate
State
State

Camptothecin is typically in a solid state at room temperature. It is often supplied as a solid crystalline powder for medical and research use.

Melting point (Celsius)
267.00
Melting point (Kelvin)
540.15
Boiling point (Celsius)
545.50
Boiling point (Kelvin)
818.65
General information
Molecular weight
348.35g/mol
Molar mass
348.3520g/mol
Density
1.3600g/cm3
Appearence

Camptothecin is a yellow crystalline compound. It is typically a pale yellow color and is usually provided as a powder for use in laboratory research.

Comment on solubility

Solubility of 13-hydroxy-8,14,19-trimethoxy-4,10,12,16-tetramethyl-3,20,22-trioxo-2-azabicyclo[16.3.1]docosa-1(21),4,6,10,18-pentaen-9-yl carbamate

The solubility of the compound with the formula C20H16N2O5 can vary significantly based on several factors, including temperature, pH, and the nature of the solvent. Here are some key points that characterize the solubility properties of this compound:

  • Polarity: The presence of multiple functional groups, including carbamate and methoxy groups, suggests that this compound may exhibit polar characteristics.
  • Solvents: It is likely to be soluble in polar solvents such as:
    • Water
    • Dimethyl sulfoxide (DMSO)
    • Ethanol
  • Temperature Dependence: Generally, an increase in temperature can enhance solubility. Thus, heating may assist in dissolving this compound more effectively.
  • pH Influence: The solubility may also be pH-dependent, where the ionization state of the functional groups can alter its ability to dissolve in various solvents.

In summary, while the exact solubility data may not be readily available, the structural features of the compound indicate a potential for solubility in polar environments, influenced by environmental conditions and solvent interactions.

Interesting facts

Interesting Facts about 13-Hydroxy-8,14,19-trimethoxy-4,10,12,16-tetramethyl-3,20,22-trioxo-2-azabicyclo[16.3.1]docosa-1(21),4,6,10,18-pentaen-9-yl Carbamate

This compound presents a complex structure that embodies the intricate nature of organic chemistry. The name alone suggests a rich diversity of functional groups and a unique stereochemistry, which can lead to several interesting properties and potential applications.


Chemical Structure and Features

  • Functional Diversity: The presence of multiple methoxy groups and a carbamate moiety allows for unique reactivity patterns and polar characteristics.
  • Cyclic Framework: The azabicyclo structure indicates a bicyclic compound exhibiting a complex three-dimensional conformation that could influence its biological activity.
  • Potential Applications: Given its complex structure, this compound might exhibit interesting pharmaceutical properties, particularly in drug design and development.

Conclusion

While the specific applications and properties of this carbamate are subject to ongoing research, it is essential to note that compounds with intricate structures like this often lead to innovative discoveries in various fields, including medicinal chemistry, materials science, and organic synthesis. As we continue to understand its capabilities, this compound could pave the way for future advancements in chemical science.

Synonyms
geldanamycin
30562-34-6
(13-Hydroxy-8,14,19-trimethoxy-4,10,12,16-tetramethyl-3,20,22-trioxo-2-azabicyclo[16.3.1]docosa-1(21),4,6,10,18-pentaen-9-yl) carbamate
NSC 122750
carbamic acid (6-hydroxy-5,11,21-trimethoxy-3,7,9,15-tetramethyl-16,20,22-trioxo-17-azabicyclo[16.3.1]docosa-1(21),8,12,14,18-pentaen-10-yl) ester
HMS3656P15
13-Hydroxy-8,14,19-trimethoxy-4,10,12,16-tetramethyl-3,20,22-trioxo-2-azabicyclo[16.3.1]docosa-1(21),4,6,10,18-pentaen-9-yl carbamate
SMP1_000132
SY074810
Q27163406