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Artemisinin

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Identification
Molecular formula
C15H22O5
CAS number
63968-64-9
IUPAC name
13-hydroxy-6-isopropenyl-16,17-dimethoxy-2,7,20-trioxapentacyclo[11.8.0.03,11.04,8.014,19]henicosa-3(11),9,14,16,18-pentaen-12-one
State
State
Artemisinin is typically a solid at room temperature. It maintains stability in its solid state under standard storage conditions and is typically handled as a fine crystalline powder.
Melting point (Celsius)
157.00
Melting point (Kelvin)
430.00
Boiling point (Celsius)
295.00
Boiling point (Kelvin)
568.00
General information
Molecular weight
282.33g/mol
Molar mass
282.3320g/mol
Density
1.3500g/cm3
Appearence

Artemisinin is a white crystalline powder. It is a natural compound commonly isolated from the sweet wormwood plant, Artemisia annua. Its appearance can be described as a solid with clear crystalline form under the microscope.

Comment on solubility

Solubility of 13-hydroxy-6-isopropenyl-16,17-dimethoxy-2,7,20-trioxapentacyclo[11.8.0.03,11.04,8.014,19]henicosa-3(11),9,14,16,18-pentaen-12-one (C15H22O5)

The solubility of 13-hydroxy-6-isopropenyl-16,17-dimethoxy-2,7,20-trioxapentacyclo[11.8.0.03,11.04,8.014,19]henicosa-3(11),9,14,16,18-pentaen-12-one, a complex polycyclic compound, is an intriguing subject of study. This chemical structure inherently affects its solubility characteristics due to the presence of multiple functional groups.

  • Polar and Non-Polar Characteristics: The presence of hydroxyl (–OH) and methoxy (–OCH3) groups suggest a degree of polarity, which can enhance solubility in polar solvents like water.
  • Hydrophobic Regions: Conversely, the extensive carbon framework and isopropenyl group may impart hydrophobic properties, limiting its solubility in aqueous environments.
  • Solvent Interactions: It is likely to exhibit increased solubility in organic solvents such as ethanol, methanol, or dichloromethane, where the non-polar regions can interact more favorably with the solvent molecules.
  • pH Influence: The solubility may also vary with pH, particularly because hydroxyl groups can ionize, further affecting its solubility profile in solution.

The interplay of these factors illustrates how solubility in complex compounds like this one is not straightforward but rather influenced by a balance between polar and non-polar characteristics. In summary, one could say that while the compound may readily dissolve in suitable organic solvents, its behavior in water may be considerably more limited, reflecting the intricate nature of its structure.

Interesting facts

Interesting Facts about 13-Hydroxy-6-isopropenyl-16,17-dimethoxy-2,7,20-trioxapentacyclo[11.8.0.03,11.04,8.014,19]henicosa-3(11),9,14,16,18-pentaen-12-one

This unique compound, often referred to for its intriguing structural complexity, is a member of a unique class of organic molecules known as tricyclic terpenes. Here are some captivating aspects of this compound:

  • Structural Diversity: The compound features a tangled framework with multiple rings, showcasing nature's ability to create elaborate molecular architectures.
  • Biological Relevance: Compounds of this nature are often investigated for their biological activities, which could include anti-inflammatory and antimicrobial properties.
  • Natural Sources: It is of interest to study how such compounds are synthesized in nature, typically through the metabolic processes of plants or fungi.
  • Synthetic Challenges: The synthesis of such complex molecules poses significant challenges to chemists, requiring innovative strategies and techniques in organic synthesis.
  • Research Potential: Given its unique structure, this compound may have potential applications in pharmaceuticals or as novel materials in various industries.

As a chemist or chemistry student delving into the world of organic compounds, exploring such molecules not only deepens understanding of chemical principles but also ignites curiosity about their practical implications in modern science. The study of compounds like this illuminates the intricate relationships between structure and function, an essential theme in the field of chemistry.

In the words of renowned chemist Linus Pauling, “The best way to have a good idea is to have lots of ideas.” Investigating the myriad possibilities that arise from complex compounds can lead to groundbreaking discoveries!