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Phetharbital

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Identification
Molecular formula
C12H13NO2
CAS number
1150-62-5
IUPAC name
1,3-dimethyl-3-phenyl-pyrrolidine-2,5-dione
State
State

The compound is generally in a solid state at room temperature, characterized by its crystalline structure.

Melting point (Celsius)
121.50
Melting point (Kelvin)
394.65
Boiling point (Celsius)
346.70
Boiling point (Kelvin)
619.85
General information
Molecular weight
217.24g/mol
Molar mass
217.2570g/mol
Density
1.2540g/cm3
Appearence

Phetharbital typically appears as a white crystalline solid. It may also occur in powder form and is known for its stability in solid state.

Comment on solubility

Solubility of 1,3-Dimethyl-3-phenyl-pyrrolidine-2,5-dione

The solubility of 1,3-dimethyl-3-phenyl-pyrrolidine-2,5-dione is an intriguing aspect of this compound, influenced by its unique structure. As a pyrrolidine derivative, it exhibits several important characteristics:

  • Polarity: The compound's structure, featuring both polar and non-polar elements, can lead to varied solubility in different solvents.
  • Solvent Compatibility: Generally, polar solvents such as water or alcohols may facilitate dissolution, although the presence of phenyl and methyl groups might hinder complete solubility.
  • Temperature Effect: Increased temperature often enhances solubility, making it critical to consider thermal conditions when preparing solutions.

When discussing solubility, it's essential to note that:

  1. **Hydrogen bonding** can significantly affect solubility in aqueous environments.
  2. **Ionic interactions** may play a role when dealing with salts or ionized forms of similar compounds.
  3. **Ester and ketone groups**, present in the structure, further contribute to solvent interactions, affecting overall solubility profiles.

Ultimately, while the exact solubility of 1,3-dimethyl-3-phenyl-pyrrolidine-2,5-dione may vary, understanding these factors is crucial for practical applications in chemical formulations.

Interesting facts

Interesting Facts about 1,3-Dimethyl-3-phenyl-pyrrolidine-2,5-dione

1,3-Dimethyl-3-phenyl-pyrrolidine-2,5-dione, commonly known in scientific circles for its diverse applications and unique structure, is a fascinating compound that warrants exploration. Here are some interesting insights:

  • Chemical Structure: This compound features a pyrrolidine ring which is a five-membered ring containing nitrogen. The presence of both methyl and phenyl groups enhances its chemical reactivity and potential for diverse applications.
  • Biological Significance: Research indicates that derivatives related to this compound may exhibit pharmacological properties. For instance, compounds with similar structures are often studied for their potential roles as anti-inflammatory or analgesic agents.
  • Applications in Organic Synthesis: The unique structure of 1,3-dimethyl-3-phenyl-pyrrolidine-2,5-dione makes it a valuable intermediate in the synthesis of various organic compounds. Its reactivity can be harnessed to create new materials and chemicals in laboratories.
  • Stability and Reactivity: Its dione functional groups provide sites for further chemical reactions, leading to the formation of various products. This feature is particularly attractive to chemists looking to develop new compounds with specific properties.
  • Research Trends: There is ongoing research into pyrrolidine derivatives, with studies focusing on their potential uses in medicinal chemistry and materials science, showcasing the evolution of this compound's importance over time.

In conclusion, 1,3-dimethyl-3-phenyl-pyrrolidine-2,5-dione not only has intriguing structural characteristics but also plays a significant role in various fields of chemistry and biology. As scientists continue to explore its properties, this compound may unveil more uses and insights that could transform our understanding of related chemical substances.

Synonyms
METHSUXIMIDE
Mesuximide
77-41-8
Celontin
1,3-dimethyl-3-phenylpyrrolidine-2,5-dione
Methsuximid
Petinutin
Metsuccimide
Mesuximidum
mesuximid
alpha-Methylphensuximide
N,2-Dimethyl-2-phenylsuccinimide
1,3-Dimethyl-3-phenylsuccinimide
Mesuximida
Metosuccimmide [DCIT]
Metosuccimmide
Mesuximidum [INN-Latin]
1,3-Dimethyl-3-phenyl-2,5-dioxopyrrolidine
Mesuximida [INN-Spanish]
1,3-Dimethyl-3-phenyl-2,5-pyrrolidinedione
1,3-Dimethyl-3-phenyl-pyrrolidin-2,5-dione
2,5-Pyrrolidinedione, 1,3-dimethyl-3-phenyl-
N-Methyl-alpha-methyl-alpha-phenylsuccinimide
alpha-Methyl-alpha-phenyl N-methyl succinimide
PM 396
(RS)-1,3-Dimethyl-3-phenyl-2,5-pyrrolidindion
Succinimide, N,2-dimethyl-2-phenyl-
Methsuximide (USP)
HSDB 3124
EINECS 201-026-7
Mesuximide (INN)
Mesuximide [INN]
NSC-760075
UNII-0G76K8X6C0
BRN 0168315
Methsuximide [USP]
DTXSID5023293
0G76K8X6C0
MFCD00072132
DTXCID603293
5-21-11-00209 (Beilstein Handbook Reference)
NSC 760075
NCGC00189077-01
Mesuximidum (INN-Latin)
Mesuximida (INN-Spanish)
MESUXIMIDE (MART.)
MESUXIMIDE [MART.]
(+/-)-N,2-DIMETHYL-2-PHENYLSUCCINIMIDE
METHSUXIMIDE (USP-RS)
METHSUXIMIDE [USP-RS]
2,5-PYRROLIDINEDIONE,1,3-DIMETHYL-3-PHENYL-, (+/-)-
METHSUXIMIDE (USP MONOGRAPH)
METHSUXIMIDE [USP MONOGRAPH]
Celontin (TN)
(+/-)-Mesuximide
(+-)-N,2-Dimethyl-2-phenylsuccinimide
Mesuximide; Celontin
Methsuximide (Standard)
METHSUXIMIDE [MI]
.alpha.-Methylphensuximide
CHEMBL697
2,5-Pyrrolidinedione,1,3-dimethyl-3-phenyl-
METHSUXIMIDE [HSDB]
MESUXIMIDE [WHO-DD]
METHSUXIMIDE [VANDF]
SCHEMBL34852
CHEBI:6846
GTPL7228
2,5-Pyrrolidinedione,1,3-dimethyl-3-phenyl-, (+-)-
HY-B1376R
N03AD03
HMS3264P21
METHSUXIMIDE [ORANGE BOOK]
Pharmakon1600-01505443
HY-B1376
Tox21_113613
AC9293
NSC760075
AKOS015962173
CCG-213444
DB05246
CAS-77-41-8
AC-15963
AS-88007
DA-65373
SY251111
1ST165599
CS-0013113
NS00008219
1,3-Dimethyl-3-phenyl-2,5-pyrrolidinedione #
D00404
SBI-0653356.0001
AB01563316_01
EN300-9537236
N-Methyl-.alpha.,.alpha.-methylphenylsuccinimide
N-Methyl-.alpha.-methyl-.alpha.-phenylsuccinimide
Q906414
SR-01000942246
.alpha.-Methyl-.alpha.-phenyl N-methyl succinimide
SR-01000942246-1
BRD-A57592049-001-01-6
Z649373426
201-026-7