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Taxol

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Identification
Molecular formula
C47H51NO14
CAS number
33069-62-4
IUPAC name
[13-acetoxy-1,6-dihydroxy-8-(hydroxymethyl)-4,12,12,15-tetramethyl-5-oxo-14-tetracyclo[8.5.0.02,6.011,13]pentadeca-3,8-dienyl] 2-(methylamino)benzoate
State
State
Taxol is typically found in a solid state at room temperature, specifically as a crystalline powder, which is typical for many organic compounds utilized in pharmaceuticals.
Melting point (Celsius)
213.00
Melting point (Kelvin)
486.15
Boiling point (Celsius)
257.00
Boiling point (Kelvin)
530.15
General information
Molecular weight
853.91g/mol
Molar mass
853.9060g/mol
Density
1.7370g/cm3
Appearence

Taxol appears as a white to off-white crystalline powder. It is known for its crystalline structure which is characteristic of many organic compounds used in medicinal chemistry.

Comment on solubility

Solubility of 13-acetoxy-1,6-dihydroxy-8-(hydroxymethyl)-4,12,12,15-tetramethyl-5-oxo-14-tetracyclo[8.5.0.02,6.011,13]pentadeca-3,8-dienyl 2-(methylamino)benzoate (C47H51NO14)

The solubility of this compound presents a complex profile due to its intricate structure, which comprises multiple functional groups. Here are some key points to consider:

  • Polarity: The presence of hydroxyl (-OH) groups typically enhances water solubility. However, the overall polarity must be considered in context with the larger hydrocarbon segments of the molecule.
  • Hydrogen Bonding: Compounds with -OH or -NH groups often engage in hydrogen bonding, which can improve solubility in polar solvents like water.
  • Hydrophobic Character: The extensive hydrocarbon framework may hinder solubility in polar solvents, leading to a possible preference for non-polar environments.
  • Organic Solvents: This compound may find better solubility in organic solvents such as methanol, ethanol, or DMSO, which can accommodate large, hydrophobic molecules.

In summary, while the compound has functional groups conducive to solubility, its significant hydrophobic regions suggest that careful selection of solvent is essential for effective dissolution. As with many complex organic compounds, the balance between hydrophobicity and hydrophilicity ultimately dictates its solubility behavior.

Interesting facts

Exploring the Unique Compound: 13-Acetoxy-1,6-dihydroxy-8-(hydroxymethyl)-4,12,12,15-tetramethyl-5-oxo-14-tetracyclo[8.5.0.02,6.011,13]pentadeca-3,8-dienyl 2-(methylamino)benzoate

This fascinating compound, with its intricate structure, belongs to the class of complex organic molecules known as tetracyclic compounds. Characterized by multiple fused ring systems, tetracyclic compounds often possess unique biological activities that make them a subject of significant research interest.

Key Features of the Compound

  • Versatile Applications: Due to its intricate structure, this compound may exhibit various pharmacological properties, potentially serving as a lead compound in drug development.
  • Natural Origins: Similar structures can be found in various natural products, highlighting the importance of understanding structural relationships in medicinal chemistry.
  • Multifunctionality: The presence of multiple functional groups, such as hydroxyl and acetoxy, suggest it may offer sites for further chemical modifications that can enhance its biological activity.

The complex ring structure indicates that the compound could be involved in interesting mechanistic pathways when interacting with biological targets. Researchers often utilize computational methods to model such interactions, helping to predict how minor structural changes can lead to significant differences in activity. As stated by famous chemist Linus Pauling, "The best way to have a good idea is to have a lot of ideas." This encourages chemists to explore the potential of such compounds fully.

Future Prospects

As we continue to enhance our understanding of compounds like this one, the potential for discovering innovative therapeutic agents could be immense. Continued research may yield exciting insights into how these multifaceted structures play a role in biochemistry, paving the way for new treatments and enhancements in synthetic methodologies.

Synonyms
FDA99807