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1,2,3,6-Tetrahydropyridine-4-carboxylic acid

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Identification
Molecular formula
C6H9NO2
CAS number
1450-94-8
IUPAC name
1,2,3,6-tetrahydropyridine-4-carboxylic acid
State
State

At room temperature, it is found in a crystalline solid state.

Melting point (Celsius)
180.00
Melting point (Kelvin)
453.15
Boiling point (Celsius)
285.00
Boiling point (Kelvin)
558.15
General information
Molecular weight
129.14g/mol
Molar mass
129.1370g/mol
Density
1.2500g/cm3
Appearence

It is typically a white to off-white solid.

Comment on solubility

Solubility of 1,2,3,6-tetrahydropyridine-4-carboxylic acid

1,2,3,6-tetrahydropyridine-4-carboxylic acid (C6H9NO2) exhibits interesting solubility properties due to its molecular structure. Here are some key points regarding its solubility:

  • Polar Nature: The presence of the carboxylic acid group (-COOH) renders the compound polar, which generally enhances solubility in polar solvents, particularly water.
  • Hydrogen Bonding: The ability to form hydrogen bonds with water molecules contributes significantly to its solubility profile. "The more hydrogen bonds a molecule can form, the greater its solubility in water."
  • Temperature Dependency: Like many organic compounds, solubility may increase with temperature; hence, higher temperatures can facilitate dissolution.
  • Solvent Variability: Besides water, this compound may also show solubility in other polar organic solvents such as ethanol or methanol, while being less soluble in non-polar solvents.

In conclusion, 1,2,3,6-tetrahydropyridine-4-carboxylic acid demonstrates a clear preference for polar solvents, making it soluble in environments conducive to hydrogen bonding. This characteristic is vital for its applications in chemical reactions and various fields of research.

Interesting facts

Interesting Facts about 1,2,3,6-Tetrahydropyridine-4-carboxylic Acid

1,2,3,6-tetrahydropyridine-4-carboxylic acid is a fascinating compound with various implications in both chemical research and practical applications. Here are some compelling aspects of this compound:

  • Structural Significance: The molecule features a tetrahydropyridine ring, which is notable for its versatile reactivity, allowing it to engage in diverse chemical reactions.
  • Biological Relevance: This compound acts as a building block in the synthesis of various biologically active molecules, making it valuable in pharmaceutical and medicinal chemistry.
  • Functional Derivatives: Its carboxylic acid functional group allows for further chemical modifications, leading to a wide range of derivatives that could exhibit different biological or chemical properties.
  • Industrial Usage: Compounds like 1,2,3,6-tetrahydropyridine-4-carboxylic acid can be utilized in the creation of agrochemicals or specialty polymers, expanding their utility beyond just research.
  • Research Applications: In laboratory settings, this compound can serve as a reagent in organic synthesis or as a probe for studying reaction mechanisms, showcasing its importance in advancing chemical knowledge.

In summary, 1,2,3,6-tetrahydropyridine-4-carboxylic acid represents a critical intersection of structural uniqueness and practical application, emphasizing the role of chemistry in both theoretical and applied sciences. As we continue to explore its properties, we unlock potential innovations that could greatly benefit various industries.

Synonyms
isoguvacine
64603-90-3
1,2,3,6-tetrahydropyridine-4-carboxylic acid
1,2,3,6-Tetrahydro-pyridine-4-carboxylic acid
4-Pyridinecarboxylic acid, 1,2,3,6-tetrahydro-
1,2,3,6-Tetrahydro-4-pyridinecarboxylic acid
YTF580771Y
CHEMBL39071
CHEBI:34799
DTXSID30214855
UNII-YTF580771Y
MFCD01365699
AC1OEMUS
Spectrum_001974
Tocris-0235
Lopac-G-002
Spectrum3_001869
Biomol-NT_000254
Lopac0_000561
BSPBio_003318
KBioSS_002540
DivK1c_000115
SCHEMBL339700
BPBio1_000882
GTPL4226
KBio1_000115
KBio2_002531
KBio2_005099
KBio2_007667
KBio3_002820
DTXCID60137346
KRVDMABBKYMBHG-UHFFFAOYSA-N
NINDS_000115
BDBM50032955
STK504020
ZINC03872953
AKOS006343506
CCG-204651
SB38116
SDCCGSBI-0050544.P003
IDI1_000115
NCGC00015456-01
NCGC00015456-02
NCGC00015456-03
NCGC00015456-04
NCGC00015456-05
NCGC00015456-09
NCGC00024509-01
NCGC00024509-02
NCGC00024509-03
DA-17730
1,2,3,6-tetrahydropyridinium-4-carboxylate
CS-0342300
EN300-152783
1,2,3,6-tetrahydropyridin-1-ium-4-carboxylate
Q6085784
BRD-K66480997-003-10-0
1,2,3,6-Tetrahydropyridine-4-carboxylic Acid (Isoguvacine)
4-Pyridinecarboxylic acid, 1,2,3,6-tetrahydro-; 1,2,3,6-Tetrahydropyridine-4-carboxylic acid;