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1,2,3,4-Tetrahydroisoquinoline-7-sulfonamide

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Identification
Molecular formula
C9H12N2O2S
CAS number
Not Available
IUPAC name
1,2,3,4-tetrahydroisoquinoline-7-sulfonamide
State
State

At room temperature, 1,2,3,4-Tetrahydroisoquinoline-7-sulfonamide is generally in a solid state. It is common for organic compounds of this nature to exist as a crystalline solid under ambient conditions.

Melting point (Celsius)
172.00
Melting point (Kelvin)
445.15
Boiling point (Celsius)
256.00
Boiling point (Kelvin)
529.15
General information
Molecular weight
198.26g/mol
Molar mass
198.2640g/mol
Density
1.3450g/cm3
Appearence

1,2,3,4-Tetrahydroisoquinoline-7-sulfonamide appears as a white to off-white crystalline solid. The compounds of similar structure are typically fine and powdery, and their appearance can vary slightly depending on the purity and specific manufacturing process.

Comment on solubility

Solubility of 1,2,3,4-tetrahydroisoquinoline-7-sulfonamide (C9H12N2O2S)

1,2,3,4-tetrahydroisoquinoline-7-sulfonamide exhibits noteworthy solubility characteristics, which are influenced by its molecular structure. Here are some key points to consider:

  • Solvent Interaction: This compound tends to be more soluble in polar solvents due to the presence of its sulfonamide functional group, which can engage in hydrogen bonding with water molecules.
  • Aqueous Solubility: It demonstrates moderate solubility in aqueous solutions, making it more accessible for biological processes.
  • pH Dependency: The solubility can vary with pH; it is often more soluble at alkaline pH levels, which can enhance the ionization of the sulfonamide group.
  • Temperature Influence: Increasing the temperature generally increases solubility for many organic compounds, and this is observed with 1,2,3,4-tetrahydroisoquinoline-7-sulfonamide as well.

In summary, the solubility of 1,2,3,4-tetrahydroisoquinoline-7-sulfonamide is characterized by:
- Enhanced solubility in polar solvents
- Moderate aqueous solubility
- pH-dependent solubility
- Increased solubility with temperature

This combination of properties is crucial for its utility in various chemical and pharmaceutical applications.

Interesting facts

Interesting Facts about 1,2,3,4-Tetrahydroisoquinoline-7-sulfonamide

1,2,3,4-Tetrahydroisoquinoline-7-sulfonamide is an intriguing compound that has captured the interest of researchers due to its diverse applications and unique structural features. Here are some key highlights:

  • Structural Uniqueness: The compound features a tetrahydroisoquinoline core, which is a bicyclic structure known to exhibit various biological activities, including antitumor and antimicrobial properties.
  • Pharmaceutical Relevance: Research has suggested potential therapeutic uses of sulfonamide derivatives in treating various diseases. The sulfonamide moiety is well known for its role in antibiotic development, making this compound relevant in medicinal chemistry.
  • Research Applications: It serves as an important structure in the synthesis of other compounds, playing a vital role in the development of new drugs and materials in the pharmaceutical industry.
  • Biological Activity: Compounds related to tetrahydroisoquinoline have been shown to inhibit certain enzymes and interact with various biological pathways, making them a subject of interest for drug design.
  • Source of Inspiration: The chemical structure of 1,2,3,4-tetrahydroisoquinoline-7-sulfonamide serves as an inspiration for synthetic organic chemists, driving innovative approaches in organic synthesis and compound modification.

In summary, 1,2,3,4-tetrahydroisoquinoline-7-sulfonamide is not just an obscure name in organic chemistry; rather, it represents a collaborative crossroads of drug discovery, biological research, and synthetic chemistry. As scientists continue to explore its potential, this compound stands out as a beacon of possibilities in the ever-evolving field of chemistry.

Synonyms
1,2,3,4-Tetrahydroisoquinoline-7-sulfonamide
31404-61-2
Skf 29661
1,2,3,4-Tetrahydro-7-isoquinolinesulfonamide
SK&F-29661
sk&f 29661
1,2,3,4-TETRAHYDRO-ISOQUINOLINE-7-SULFONIC ACID AMIDE
SKF-29661
7ASE44P9QJ
CHEMBL26717
DTXSID20185328
7-Isoquinolinesulfonamide, 1,2,3,4-tetrahydro-
TETRAHYDRO-7-ISOQUINOLINE SULFONAMIDE, 1,2,3,4-
1hnn
MFCD11577101
SK-29661
UNII-7ASE44P9QJ
SKF
SCHEMBL1487047
BDBM13017
DTXCID30107819
UGLLZXSYRBMNOS-UHFFFAOYSA-N
DB03468
NS00071641
T90100
EN300-5423678
Q27094399