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1,2-Dihydropyrimidine

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Identification
Molecular formula
C4H6N2
CAS number
1638-37-3
IUPAC name
1,2-dihydropyrimidine
State
State

At room temperature, 1,2-dihydropyrimidine is typically in a solid state, though its melting point is relatively low, so it can transition to a liquid phase under slightly elevated temperatures.

Melting point (Celsius)
32.00
Melting point (Kelvin)
305.15
Boiling point (Celsius)
219.00
Boiling point (Kelvin)
492.15
General information
Molecular weight
84.12g/mol
Molar mass
84.1160g/mol
Density
1.0087g/cm3
Appearence

1,2-Dihydropyrimidine is typically found as a colorless crystalline powder. It is characterized by its distinct crystal structure that resembles plates. This compound is relatively stable under normal conditions and is used as an intermediate in various chemical reactions.

Comment on solubility

Solubility of 1,2-Dihydropyrimidine (C4H6N2)

1,2-Dihydropyrimidine is an intriguing compound when considering its solubility characteristics. The solubility of this compound can be influenced by several factors, such as its molecular structure and the polarity of its functional groups.

General Solubility Properties

1,2-Dihydropyrimidine exhibits the following solubility traits:

  • Polar Solvents: It is generally more soluble in polar solvents, owing to its ability to engage in hydrogen bonding and dipole-dipole interactions.
  • Water Solubility: While 1,2-dihydropyrimidine is moderately soluble in water, its actual solubility can vary with temperature and pH levels.
  • Organic Solvents: It shows a better solubility profile in organic solvents like ethanol and methanol, which align with its molecular characteristics.

Factors Influencing Solubility

Several factors can affect the solubility of 1,2-dihydropyrimidine:

  • Temperature: Increased temperatures generally enhance solubility in many solvents.
  • Presence of Other Solutes: The presence of ions or other solutes can significantly impact solubility due to interactions that may occur.
  • pH Levels: Changes in pH can alter the ionization state of the compound, which influences solubility.

In conclusion, the solubility of 1,2-dihydropyrimidine is a complex property dictated by multiple factors. This compound’s behavior in different solvent environments underscores the importance of understanding solubility dynamics in chemical research and applications.

Interesting facts

Interesting Facts About 1,2-Dihydropyrimidine

1,2-dihydropyrimidine, a compound featuring a unique bicyclic structure, belongs to the larger family of pyrimidines, which are heterocyclic aromatic compounds. This molecule is particularly intriguing due to its role in various chemical reactions and biological applications. Here are some fascinating points:

  • Structural Insights: The 1,2-dihydropyrimidine structure consists of a six-membered ring containing two nitrogen atoms, which contributes to its reactivity and interaction with biological systems.
  • Versatile Intermediate: This compound often serves as a versatile intermediate in the synthesis of various pharmaceuticals and agrochemicals due to its ability to undergo various chemical transformations.
  • Biological Significance: 1,2-dihydropyrimidines are of interest in medicinal chemistry because they can function as precursors or tunable units for compounds with potential anti-cancer and anti-viral properties.
  • Catalytic Applications: They have been explored as catalysts in organic transformations, showcasing their efficiency and roles in promoting greener synthesis pathways.
  • Natural Occurrences: Certain derivatives of 1,2-dihydropyrimidine can be found in natural products, highlighting their significance in biology and natural product synthesis.

As a student or scientist, recognizing the importance of 1,2-dihydropyrimidine in both synthetic and biological contexts opens up numerous avenues for research and discovery. In the words of organic chemist Jean-Marie Lehn, "Molecular recognition is at the heart of life and biochemistry," and compounds like 1,2-dihydropyrimidine are essential players in this intricate dance of molecular interactions.

Synonyms
dihydropyrimidine
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AKOS006350102
88985-64-2
DB-126713