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Pristimerin

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Identification
Molecular formula
C30H40O4
CAS number
1258-84-0
IUPAC name
11-hydroxy-8-(2-hydroxyacetyl)-9,13-dimethyl-6-propyl-5,7-dioxapentacyclo[10.8.0.02,9.04,8.013,18]icosa-14,17-dien-16-one
State
State

Pristimerin is typically a solid at room temperature.

Melting point (Celsius)
245.00
Melting point (Kelvin)
518.15
Boiling point (Celsius)
461.10
Boiling point (Kelvin)
734.25
General information
Molecular weight
468.62g/mol
Molar mass
468.6150g/mol
Density
1.2700g/cm3
Appearence

Pristimerin is typically a white to off-white solid. It may appear as a crystalline powder depending on its preparation and purity.

Comment on solubility

Solubility Characteristics

The compound 11-hydroxy-8-(2-hydroxyacetyl)-9,13-dimethyl-6-propyl-5,7-dioxapentacyclo[10.8.0.02,9.04,8.013,18]icosa-14,17-dien-16-one with the formula C30H40O4 presents intriguing solubility properties that are influenced by its complex structure.

Solubility in Different Solvents

When discussing solubility, it is essential to consider the following factors:

  • Polarity: The presence of multiple hydroxyl (-OH) groups typically increases the polarity of a compound, enhancing its solubility in polar solvents like water.
  • Hydrophobic Interactions: However, the large hydrophobic regions resulting from the extensive hydrocarbon framework may limit water solubility.
  • Organic Solvents: This compound is likely more soluble in organic solvents such as ethanol or methanol, where both hydrogen bonding and hydrophobic interactions can play a significant role.

Solubility Insights

Some additional insights into its solubility include:

  • Compounds of similar structure often exhibit solubility trends that can be generalized, indicating possible behavior in different solvent systems.
  • Experimental data may show variations depending on temperature and pH, which can affect the ionization state of functional groups.
  • The solubility will also depend on the specific experimental conditions and concentrations tested.

In summary, understanding the solubility of this compound requires a multi-faceted approach, taking into account both its chemical structure and the solvents used. Given its unique composition, further experimental exploration is essential to delineate its precise solubility profile.

Interesting facts

Interesting Facts about 11-Hydroxy-8-(2-hydroxyacetyl)-9,13-dimethyl-6-propyl-5,7-dioxapentacyclo[10.8.0.02,9.04,8.013,18]icosa-14,17-dien-16-one

This fascinating compound, with its extensive and complex structure, exemplifies the intricate nature of organic chemistry. Compounds like this one often feature in discussions around natural product synthesis due to their unique frameworks and functional groups.

Key Characteristics

  • Structural Diversity: The polycyclic structure of this compound contributes to its potential reactivity and interaction with biological systems.
  • Functional Groups: The presence of hydroxyl groups (–OH) and a ketone group (–C=O) enhances its polarity and may confer various physiological activities.
  • Natural Occurrence: Compounds with similar structures are frequently derived from natural sources, particularly in plants, where they serve essential roles in biochemistry.

Applications

  • Pharmaceutical Research: Due to the presence of multiple functional groups, this compound could be a candidate for further research in drug development, particularly in understanding its potential therapeutic effects.
  • Biochemical Significance: Largely studied for its role in biological pathways, compounds like this are crucial in exploring various biochemical interactions.

As we venture deeper into the study of complex organic molecules, the importance of compounds such as this cannot be overstated. They inspire a profound appreciation for the diverse assembly of atoms and the potential they hold for new scientific discoveries. As the famous chemist Linus Pauling once said, “The way to be successful is to have your heart in your business, and your business in your heart.” In the realm of chemical compounds, this sentiment resonates strongly as we explore the heart of chemistry and its impact on our world.

Synonyms
51372-29-3
(R)-Budesonide
51333-22-3
Budesonide-d6
(22R)-Budesonide
11-Hydroxy-8-(2-hydroxyacetyl)-9,13-dimethyl-6-propyl-5,7-dioxapentacyclo[10.8.0.02,9.04,8.013,18]icosa-14,17-dien-16-one
5-hydroxy-6b-(hydroxyacetyl)-4a,6a-dimethyl-8-propyl-4a,4b,5,6,6a,6b,9a,10,10a,10b,11,12-dodecahydro-2H-naphtho[2',1':4,5]indeno[1,2-d][1,3]dioxol-2-one
Pregna-1,4-diene-3,20-dione, 16,17-[butylidenebis(oxy)]-11,21-dihydroxy-, (11.beta.,16.alpha.)-
Pregna-1,4-diene-3,20-dione,16,17-[(1R)-butylidenebis(oxy)]-11,21-dihydroxy-, (11b,16a)-
CHEMBL3188153
SCHEMBL13026143
CHEBI:91899
VOVIALXJUBGFJZ-UHFFFAOYSA-N
HMS3269L17
1134189-63-1
FUB54294
LSM-1835
STL356043
AKOS022060653
NCGC00015165-03
NCGC00021318-02
6b-Glycoloyl-5-hydroxy-4a,6a-dimethyl-8-propyl-4a,4b,5,6,6a,6b,9a,10,10a,10b,11,12-dodecahydro-2H-naphtho[2',1':4,5]indeno[1,2-d][1,3]dioxol-2-one
AF-575/25000482
BRD-A82238138-001-01-7
Q27163696
16-.alpha.,17-.alpha.-Butylidenedioxy-11-.beta.,21-dihydroxy-1,4-pregnadiene-3,20-dione
(11-.beta.,16-.alpha.)-16,17-(Butylidenebis(oxy))-11,21-dihydroxypregna-1,4-diene-3,20-dione
(RS)-11.beta.,16.alpha.,17,21-Tetrahydroxypregna-1,4-diene-3,20-dione cyclic 16,17-acetal with butyraldehyde