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Hydrocortisone butyrate

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Identification
Molecular formula
C25H36O6
CAS number
13609-67-1
IUPAC name
[11-hydroxy-17-(2-hydroxyacetyl)-10,13-dimethyl-3-oxo-2,6,7,8,9,11,12,14,15,16-decahydro-1H-cyclopenta[a]phenanthren-17-yl] butanoate
State
State

At room temperature, hydrocortisone butyrate is a solid.

Melting point (Celsius)
207.00
Melting point (Kelvin)
480.15
Boiling point (Celsius)
292.00
Boiling point (Kelvin)
565.15
General information
Molecular weight
444.57g/mol
Molar mass
444.5690g/mol
Density
1.1200g/cm3
Appearence

Hydrocortisone butyrate appears as a white to off-white crystalline powder.

Comment on solubility

Solubility of [11-hydroxy-17-(2-hydroxyacetyl)-10,13-dimethyl-3-oxo-2,6,7,8,9,11,12,14,15,16-decahydro-1H-cyclopenta[a]phenanthren-17-yl] butanoate

The solubility characteristics of the compound with the formula C25H36O6 can be intriguing due to its intricate structure. This compound, featuring both hydroxyl and ester functional groups, likely exhibits varied solubility depending on the solvent utilized. Here are some key points to consider:

  • Hydrophilicity and Hydrophobicity: The presence of hydroxyl groups typically enhances solubility in polar solvents, while the overall hydrocarbon framework suggests a certain degree of hydrophobic character.
  • Polar vs. Nonpolar Solvents: This compound may dissolve better in polar solvents such as methanol or ethanol due to hydrogen bonding capabilities, whereas nonpolar solvents like hexane may not effectively solvate the compound.
  • Concentration Dependency: At higher concentrations, solubility may diminish due to intermolecular interactions that stabilize the solid form.
  • Potential Applications: Understanding solubility is crucial for application in biological systems, pharmaceuticals, and synthesis processes.

As always, specific solubility tests are essential to confirm these characteristics, given that solubility can be influenced by factors such as temperature, pH, and the presence of other solutes.

Interesting facts

Interesting Facts about 11-Hydroxy-17-(2-hydroxyacetyl)-10,13-dimethyl-3-oxo-2,6,7,8,9,11,12,14,15,16-decahydro-1H-cyclopenta[a]phenanthren-17-yl butanoate

This compound represents a fascinating class of organic molecules primarily studied in the field of medicinal chemistry. Here are some engaging points to consider:

  • Structural Complexity: The intricate structure includes multiple functional groups that play crucial roles in its biological activity, including hydroxy, keto, and ester functionalities.
  • Natural Products: This compound is often associated with various natural products, some of which exhibit significant pharmacological activities, including anti-inflammatory and anticancer properties.
  • Biological Activity: The unique configuration may allow for interactions with specific biological targets, making it a subject of interest in drug design and discovery. Understanding its mechanism of action is vital for potential therapeutic applications.
  • Derivatives and Syntheses: The compound's variability leads to numerous derivatives that can be synthesized, each potentially exhibiting different biological activities and stability profiles.

As a chemistry student or scientist, exploring such compounds underscores the importance of understanding structure-activity relationships (SAR) and how even slight modifications can lead to significant changes in activity. The study of compounds like this not only enhances our chemical knowledge but also pushes the boundaries of therapeutic advancements.

In summary, 11-hydroxy-17-(2-hydroxyacetyl)-10,13-dimethyl-3-oxo-2,6,7,8,9,11,12,14,15,16-decahydro-1H-cyclopenta[a]phenanthren-17-yl butanoate encapsulates the allure of medicinal chemistry, combining structural complexity with the promise of biomedical innovation. It is a reminder that every compound holds stories of its synthesis, function, and potential applications just waiting to be uncovered.

Synonyms
13609-67-1
CHEMBL1434261
SCHEMBL14936050
NCGC00159427-02
LS-15129
DB-042332