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Proline betaine

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Identification
Molecular formula
C7H13NO2
CAS number
56048-08-9
IUPAC name
1,1-dimethylpyrrolidin-1-ium-2-carboxylic acid
State
State

Proline betaine is solid at room temperature. It is typically odorless and soluble in water, making it suitable for various aqueous applications.

Melting point (Celsius)
228.00
Melting point (Kelvin)
501.00
Boiling point (Celsius)
235.00
Boiling point (Kelvin)
508.00
General information
Molecular weight
129.19g/mol
Molar mass
129.1590g/mol
Density
1.1500g/cm3
Appearence

Proline betaine typically appears as a white crystalline powder. It is hygroscopic and may clump together if exposed to moisture in the air. In solution, it appears clear and colorless.

Comment on solubility

Solubility of 1,1-dimethylpyrrolidin-1-ium-2-carboxylic acid

1,1-dimethylpyrrolidin-1-ium-2-carboxylic acid, with the chemical formula C7H13NO2, exhibits interesting solubility characteristics that can be influenced by several factors. The following points highlight its solubility behavior:

  • Polar nature: Due to the presence of the carboxylic acid functional group, this compound is relatively polar, which typically enhances its solubility in polar solvents such as water.
  • Solvent compatibility: It is likely to find better solubility in alcohols and other polar organic solvents due to the interactions between the polar groups in the molecule and the solvent molecules.
  • Ionization potential: The carboxylic acid moiety can undergo ionization, especially in aqueous solutions, leading to increased **solubility in water** when the pH is adjusted to a more basic condition.
  • Effect of temperature: As is typical for many compounds, an increase in temperature might enhance solubility as solvation increases with temperature.

In summary, while the solubility of 1,1-dimethylpyrrolidin-1-ium-2-carboxylic acid is reasonably good in polar solvents, factors such as pH and temperature can significantly affect its solubility profile. Understanding these relationships is crucial when considering its practical applications in various fields.

Interesting facts

Interesting Facts about 1,1-Dimethylpyrrolidin-1-ium-2-carboxylic Acid

1,1-Dimethylpyrrolidin-1-ium-2-carboxylic acid is a fascinating compound that blends the characteristics of pyrrolidine and a carboxylic acid, showcasing a unique structural feature that presents both chemical and biological significance:

  • Quaternary Ammonium Nature: As a quaternary ammonium compound, it possesses a positively charged nitrogen atom. This makes it an excellent candidate for exploring ionic interactions.
  • Biochemical Relevance: Compounds like this often play a role in biological systems, especially as metabolites or precursors to more complex molecules found in living organisms.
  • Potential Uses: The compound's ability to form ionic bonds may lead to applications in drug design and development, particularly in enhancing the solubility of poorly water-soluble drugs.
  • Chemical Versatility: Due to its structure, it may undergo various chemical reactions, including nucleophilic substitutions, making it valuable in synthetic chemistry.

Researchers continue to study such compounds in the quest for new therapeutic agents. As noted in studies, they could “bridge the gap between synthetic chemistry and biological applications,” leading to innovative treatments and enhanced drug delivery systems. The interplay of its structural components positions 1,1-dimethylpyrrolidin-1-ium-2-carboxylic acid as a subject of intriguing potential and discovery within the realms of both chemistry and biology.

Synonyms
dl-Stachydrine
1,1-dimethylpyrrolidin-1-ium-2-carboxylic acid
SCHEMBL171869
CHEBI:193587
CMUNUTVVOOHQPW-UHFFFAOYSA-N
NCI60_019106
PD039753
NS00015011