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Acridone

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Identification
Molecular formula
C13H9NO
CAS number
578-95-0
IUPAC name
10H-acridin-9-one
State
State

At room temperature, acridone is a solid.

Melting point (Celsius)
352.00
Melting point (Kelvin)
625.15
Boiling point (Celsius)
521.60
Boiling point (Kelvin)
794.80
General information
Molecular weight
195.22g/mol
Molar mass
195.2160g/mol
Density
1.4228g/cm3
Appearence

Acridone typically appears as yellow to yellowish-green crystalline solid.

Comment on solubility

Solubility of 10H-acridin-9-one (C13H9NO)

10H-acridin-9-one is an interesting compound, particularly when considering its solubility characteristics. The solubility of various compounds often depends on several key factors, and in the case of 10H-acridin-9-one, certain trends can be observed:

  • Polarity: 10H-acridin-9-one features a nitrogen atom in its structure, which contributes to its slightly polar nature. This can influence its interaction with solvents.
  • Solvent Compatibility: Due to its molecular structure, 10H-acridin-9-one tends to be more soluble in organic solvents such as ethanol or dimethyl sulfoxide (DMSO). However, it exhibits limited solubility in water, which can be attributed to its hydrophobic aromatic ring.
  • Stability: When dissolved, 10H-acridin-9-one may form several interactions with the solvent molecules, affecting its stability and, consequently, its solubility profile.

In summary, the solubility of 10H-acridin-9-one is enhanced in non-polar to mildly polar organic solvents while showing relatively poor solubility in water. As emphasized in many studies, understanding these solubility properties is vital for practical applications in fields such as pharmaceuticals and organic synthesis.

Interesting facts

Interesting Facts about 10H-Acridin-9-one

10H-Acridin-9-one is a fascinating compound that belongs to the class of acridines, which are heterocyclic organic compounds characterized by their unique fused ring structure. Here are some engaging facts about this intriguing compound:

  • Biological Relevance: Compounds in the acridine family exhibit a variety of biological activities, making them subjects of interest in medicinal chemistry. For instance, acridine derivatives have been studied for their potential as anti-cancer agents because of their ability to intercalate DNA.
  • Fluorescent Properties: Many acridine compounds, including 10H-acridin-9-one, show fluorescence under UV light, which has important applications in biological imaging and as labels in various chemical assays.
  • Historical Use: Acridine itself was first isolated from coal tar in the 19th century and has since found applications in dye manufacturing, particularly for fabric dyes.
  • Research Studies: Numerous studies have evaluated the derivatives of acridin-9-one for their pharmaceutical effects, with ongoing research focused on its potential therapeutic applications in treating diseases such as malaria and certain cancers.
  • Structural Characteristics: The 10H-acridin-9-one features a ketone functional group, which is crucial for its reactivity and interactions with biological molecules.

This compound, while lesser-known compared to other big players in biochemistry, continues to be a promising area for research due to its unique properties and potential applications. As a chemistry student, exploring such compounds can lead to exciting discoveries in both synthetic and applied chemistry.

Synonyms
acridone
578-95-0
9(10H)-Acridone
acridin-9(10H)-one
9-Acridone
Acridanone
9(10H)-ACRIDINONE
10H-acridin-9-one
9-Acridanone
Acridin-9-one
9(10H)-Acridanone
9,10-Dihydro-9-oxoacridine
Acridine, 9,10-dihydro-9-oxo-
MFCD00005019
CCRIS 3317
UNII-6BK306GUQA
EINECS 209-434-7
6BK306GUQA
9,10-dihydroacridin-9-one
NSC 408196
9(10H)acridone
BRN 0007104
7H-Dibenz(a,j)acrid-14-one
CHEBI:50756
AI3-00868
ACRIDIN-9-OL
NSC-408196
9,l0-Dihydro-9-oxoacridine
MLS000551242
643-62-9
DTXSID8060371
5-21-09-00007 (Beilstein Handbook Reference)
SMR000112235
Acridine,10-dihydro-9-oxo-
7H-DIBENZ[A,J]ACRID-14-ONE
9-Acridinol
9Acridanone
Acridin9one
9Acridone
9-hydroxyacridine
Acridone (Standard)
9(10H)Acridanone
9(10H)Acridinone
9(10H) acridone
9-(10H)acridone
9(10)H-Acridone
acridine, 9-hydroxy-
9-Azaanthracen-10-one
9,10Dihydro9oxoacridine
cid_2015
Acridine, 9,10dihydro9oxo
SCHEMBL19289
CHEMBL436589
9(10H)-Acridanone, 99%
DTXCID8042264
BDBM74759
NSC7664
HMS2271C03
BCP25846
HY-W007771R
NSC-7664
MFCD00127712
NSC138672
NSC408196
STK803038
AKOS000119816
AKOS002257157
CS-W007771
FA01197
HY-W007771
NSC-138672
NCGC00246256-01
AS-17382
SY035720
DB-053127
A0133
NS00006605
EN300-18139
C20142
AB00572676-08
AE-641/00183032
Q342721
Z57205009
F0486-2424
9-Acridone Acridanone Acridin-9-one Acridine, 9,10-dihydro-9-oxo- Dihydroketoacridine