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Atropine

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Identification
Molecular formula
C17H23NO3
CAS number
55-48-1
IUPAC name
(10,19-diethyl-19-hydroxy-14,18-dioxo-17-oxa-3,13-diazapentacyclo[11.8.0.02,11.04,9.015,20]henicosa-1(21),2,4(9),5,7,10,15(20)-heptaen-7-yl) 4-(1-piperidyl)piperidine-1-carboxylate
State
State
At room temperature, atropine is typically in a solid state, specifically as a crystalline powder.
Melting point (Celsius)
114.00
Melting point (Kelvin)
387.15
Boiling point (Celsius)
118.00
Boiling point (Kelvin)
391.15
General information
Molecular weight
289.37g/mol
Molar mass
289.3690g/mol
Density
1.2967g/cm3
Appearence

Atropine appears as white crystals or a white crystalline powder. It is slightly soluble in water and freely soluble in alcohol and chloroform. It is odorless with a bitter taste.

Comment on solubility

Solubility Characteristics

The solubility of the compound (10,19-diethyl-19-hydroxy-14,18-dioxo-17-oxa-3,13-diazapentacyclo[11.8.0.02,11.04,9.015,20]henicosa-1(21),2,4(9),5,7,10,15(20)-heptaen-7-yl) 4-(1-piperidyl)piperidine-1-carboxylate, C17H23NO3, is influenced by several factors:

  • Polarity: The presence of both hydrophobic and hydrophilic groups in the structure suggests that the compound may exhibit amphiphilic characteristics, potentially leading to variable solubility in various solvents.
  • Functional Groups: The presence of hydroxyl (-OH) and carbonyl (>C=O) functional groups often enhances solubility in polar solvents like water and methanol.
  • Aliphatic Chains: The diethyl substituents may render the compound less soluble in water due to their hydrophobic nature, while increasing the solubility in nonpolar solvents.

In summary, one may observe that:

  • The compound is likely soluble in organic solvents due to its hydrophobic components.
  • It may demonstrate limited solubility in aqueous solutions but can show increased solubility in mixed solvent systems.
  • Temperature and pH can further affect its solubility profile.

Understanding the solubility behavior of this compound is crucial for its applications in pharmaceuticals and materials science, as solubility plays a vital role in bioavailability and processing.

Interesting facts

Interesting Facts about 10,19-Diethyl-19-hydroxy-14,18-dioxo-17-oxa-3,13-diazapentacyclo[11.8.0.02,11.04,9.015,20]henicosa-1(21),2,4(9),5,7,10,15(20)-heptaen-7-yl 4-(1-piperidyl)piperidine-1-carboxylate

This intricate compound showcases the fascinating complexities of organic chemistry, particularly in the realm of polycyclic structures and their derivatives. Here are several highlights that make it especially noteworthy:

  • Structural Complexity: This compound features a unique pentacyclic framework, which is a testament to the versatility and ingenuity of synthetic organic chemistry. The multiple rings contribute to its unique stereochemistry.
  • Functional Diversity: The presence of both keto (oxo) and hydroxy groups suggests potential biological activity, possibly influencing its interactions within biological systems or its reactivity in synthetic pathways.
  • Pharmacological Potential: With a structure that may bear similarity to known pharmacophores, it could illustrate potential medicinal properties worth investigating. Compounds with piperidine derivatives are often recognized for their role in various therapeutic applications.
  • Research Implications: The synthetic routes required to construct such a complex compound can yield significant insights into reaction mechanisms, particularly in the context of ring formation and functionalization.
  • Potential Applications: Given its diverse functionalities, this compound could be explored for applications in drug design or materials science, potentially leading to innovative solutions in healthcare or technology.

In summary, the study of this compound broadens our understanding of synthetic strategies in organic chemistry and emphasizes the importance of structure–activity relationships in the development of new therapeutic agents. As one insightful chemist once said, “Chemistry is a science of change; molecules change, reactions change, and ideas change.” This compound exemplifies that ethos through its potential reactivity and application in various fields.

Synonyms
4,11-diethyl-4-hydroxy-3,14-dioxo-3,4,12,14-tetrahydro-1H-pyrano[3',4':6,7]indolizino[1,2-b]quinolin-9-yl 1,4'-bipiperidine-1'-carboxylate
(10,19-Diethyl-19-hydroxy-14,18-dioxo-17-oxa-3,13-diazapentacyclo[11.8.0.02,11.04,9.015,20]henicosa-1(21),2,4(9),5,7,10,15(20)-heptaen-7-yl) 4-piperidin-1-ylpiperidine-1-carboxylate
(S)-4,11-Diethyl-4-hydroxy-3,14-dioxo-3,4,12,14-tetrahydro-1H-pyrano[3 inverted exclamation mark ,4 inverted exclamation mark :6,7]indolizino[1,2-b]quinolin-9-yl [1,4 inverted exclamation mark -bipiperidine]-1 inverted exclamation mark -carboxylate
MFCD00866307
CHEMBL10456
SCHEMBL12313065
CHEBI:93762
DTXSID80861151
LSM-4269
STL483712
AKOS037483529
NCGC00167833-01
SY105303
Q27165452
4,11-Diethyl-4-hydroxy-3,14-dioxo-3,4,12,14-tetrahydro-1H-pyrano[3',4':6,7]indolizino[1,2-b]quinolin-9-yl [1,4'-bipiperidine]-1'-carboxylate