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Androstenedione

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Identification
Molecular formula
C19H26O2
CAS number
63-05-8
IUPAC name
10,13-dimethyl-2,6,7,8,9,11,12,14,15,16-decahydro-1H-cyclopenta[a]phenanthrene-3,17-dione
State
State

At room temperature, androstenedione is found as a solid crystalline powder. It is stable under normal conditions of use and storage.

Melting point (Celsius)
174.00
Melting point (Kelvin)
447.00
Boiling point (Celsius)
568.00
Boiling point (Kelvin)
841.00
General information
Molecular weight
286.40g/mol
Molar mass
286.4030g/mol
Density
1.0800g/cm3
Appearence

Androstenedione appears as a crystalline solid. It is white to off-white in color and does not possess any significant odor. The compound is typically used in its pure powdered form for scientific research and analysis.

Comment on solubility

Solubility of 10,13-dimethyl-2,6,7,8,9,11,12,14,15,16-decahydro-1H-cyclopenta[a]phenanthrene-3,17-dione

The solubility of 10,13-dimethyl-2,6,7,8,9,11,12,14,15,16-decahydro-1H-cyclopenta[a]phenanthrene-3,17-dione (C19H26O2) can be evaluated by considering its chemical structure and functional groups. The presence of a dione functional group suggests potential for interactions with polar solvents, yet the large hydrocarbon portion may render it more hydrophobic. This results in a characteristic solubility profile where:

  • In organic solvents: The compound is likely soluble in non-polar organic solvents such as hexane and toluene due to its hydrophobic nature.
  • In water: Given the limited polar character imparted by the dione groups, solubility in water is expected to be quite low, possibly leading to a precipitation.
  • In mixed solvents: Moderate solubility might be observed in mixed solvents that contain both polar and non-polar characteristics, such as ethanol or acetone.

In summary, while the compound's dione groups may provide some degree of interaction with polar solvents, its overall hydrophobic structure is likely to limit its solubility, emphasizing the importance of selecting appropriate solvents for practical applications.

Interesting facts

Facts about 10,13-Dimethyl-2,6,7,8,9,11,12,14,15,16-decahydro-1H-cyclopenta[a]phenanthrene-3,17-dione

This intriguing compound, often referred to within the scientific community for its structural complexity, embodies a unique blend of chemical features that make it a fascinating subject of study.

Structural Characteristics

  • Relatively Large Framework: The compound consists of a cyclic structure, highlighting the principles of organic chemistry in ring formation and stability.
  • Hydrogen Saturation: With multiple hydrogen atoms incorporated into its molecular structure, it represents a saturated compound, contributing to its physical properties.
  • Dimethyl Groups: The presence of two methyl groups affects its reactivity and interactions, making it a valuable candidate for further synthetic modifications.

Biological Significance

This compound is a derivative of naturally occurring steroids, which emphasizes its potential relevance in biological systems. Here are some profound aspects of its biological importance:

  • Analogous to Steroids: As a steroid-like structure, it may exhibit biological activity similar to that of steroids, possibly impacting hormonal balance.
  • Study of Metabolic Pathways: Researchers often investigate such compounds to understand metabolic pathways and their implications in human health.

Applications in Research

Due to its unique properties, this compound is of interest for various applications:

  • Pharmaceutical Development: There is potential for development in drug formulations due to its unique structural characteristics.
  • Organic Synthesis: Its complex structure serves as a model for exploration in synthetic organic chemistry, shooting for breakthroughs in the design of new compounds.

In summary, 10,13-dimethyl-2,6,7,8,9,11,12,14,15,16-decahydro-1H-cyclopenta[a]phenanthrene-3,17-dione stands out as a remarkable compound, offering a window into the intricate relationships between structure and function in organic chemistry. The study of such compounds unveils endless opportunities for innovations in science and technology.

Synonyms
4-Androsten-3,17-dione
CHEMBL274826
androstenedione-d7
NCIOpen2_003213
SCHEMBL9926734
HMS1648G10
SCA03485
BDBM50025428
AKOS001580988
AKOS017258742
NCGC00015109-02
NCGC00015109-03
NCGC00015109-04
LS-14731
DB-054395
AB01334090-02
2,15-dimethyltetracyclo[8.7.0.0^{2,7}.0^{11,15}]heptadec-6-ene-5,14-dione
(8R,9R,10R,13S,14S)-10,13-dimethyl-2,6,7,8,9,11,12,14,15,16-decahydro-1H-cyclopenta[a]phenanthrene-3,17-dione
10,13-Dimethyl-1,6,7,8,9,10,11,12,13,14,15,16-dodecahydro-2H-cyclopenta[a]phenanthrene-3,17-dione
androstenedione;androst-4-ene-3,17-dione;4-androstene-3,17-dione (androstenedione);androstenedione androst-4-ene-3,17-dione 4-androstene-3,17-dione (androstenedione)