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Clonazolam

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Identification
Molecular formula
C17H12ClN5O2
CAS number
33887-02-4
IUPAC name
10-chloro-2-methyl-11b-phenyl-2,3,5,7-tetrahydrooxazolo[3,2-d][1,4]benzodiazepin-6-one
State
State

At room temperature, clonazolam is typically in a solid state, appearing as a crystalline powder.

Melting point (Celsius)
157.00
Melting point (Kelvin)
430.15
Boiling point (Celsius)
459.00
Boiling point (Kelvin)
732.15
General information
Molecular weight
353.81g/mol
Molar mass
353.8050g/mol
Density
1.3000g/cm3
Appearence

Clonazolam typically appears as a white or off-white crystalline powder. It may sometimes be found in tablet or liquid form when used in research settings.

Comment on solubility

Solubility of 10-chloro-2-methyl-11b-phenyl-2,3,5,7-tetrahydrooxazolo[3,2-d][1,4]benzodiazepin-6-one (C17H12ClN5O2)

The solubility characteristics of 10-chloro-2-methyl-11b-phenyl-2,3,5,7-tetrahydrooxazolo[3,2-d][1,4]benzodiazepin-6-one can be quite intriguing due to its complex structure. Here are some key points regarding its solubility:

  • Polarity: The presence of various functional groups, including the chlorine atom and nitrogen atoms, suggests that this compound could exhibit moderate solubility in polar solvents.
  • Solvent Interaction: It may dissolve well in solvents like dimethyl sulfoxide (DMSO) and dimethylformamide (DMF), while showing limited solubility in non-polar solvents.
  • Temperature Effects: Temperature can significantly influence solubility; generally, increased temperature leads to enhanced solubility of solid compounds in liquids.
  • pH Sensitivity: The solubility might also vary with pH, owing to the presence of functional groups that can accept or donate protons.

To summarize, the solubility of this compound is likely moderate and highly dependent on the solvent nature and environmental conditions. As with many complex organic compounds, understanding the solubility behavior is crucial for its potential applications in pharmaceutical formulations and other chemical processes.

Interesting facts

Exploring 10-Chloro-2-methyl-11b-phenyl-2,3,5,7-tetrahydrooxazolo[3,2-d][1,4]benzodiazepin-6-one

This compound, known as 10-chloro-2-methyl-11b-phenyl-2,3,5,7-tetrahydrooxazolo[3,2-d][1,4]benzodiazepin-6-one, is a fascinating member of the benzodiazepine family, a class of compounds primarily known for their psychoactive effects. Here are some intriguing aspects of this compound:

  • Synthetic Versatility: The intricate structure of this compound allows chemists to explore various synthesis pathways, showcasing the flexibility in organic synthesis, which is crucial for developing new pharmaceuticals.
  • Pharmacological Potential: Benzodiazepines are often utilized in medicine for their tranquilizing effects. This specific compound, because of its unique structural features, may offer pathways to novel therapeutic agents.
  • Chloro-substitution Influence: The presence of the chlorine atom introduces interesting electronic characteristics, potentially enhancing the compound's interaction with biological targets. Scientists often study these modifications to optimize compound efficacy.
  • Molecular Diversity: With its oxazolo and tetrahydro features, this compound exemplifies the rich diversity found within the benzodiazepine structure. Such diversity contributes to the ongoing research aimed at discovering new compounds with unique properties.

In the world of medicinal chemistry, the study of such compounds can lead to significant breakthroughs. As quoted by renowned chemist, "Each compound is a story waiting to be told, with countless chapters waiting to unfold." This encapsulates the excitement that surrounds compounds like 10-chloro-2-methyl-11b-phenyl-2,3,5,7-tetrahydrooxazolo[3,2-d][1,4]benzodiazepin-6-one.

Overall, the exploration of this complex structure not only enhances our understanding of chemical interactions but also paves the way for potential advancements in therapeutic applications.

Synonyms
oxazolam
Oxazolazepam
Tranquit
Hializan
Serenal
24143-17-7
Convertal
Oxazolamum
Serenal [Japanese]
Oxazolam [INN:JAN]
Oxazolamum [INN-Latin]
1V2WI2NA1C
OXAZOLAM [INN]
OXAZOLAM [JAN]
OXAZOLAM [MI]
10-Chloro-2,3,7,11b-tetrahydro-2-methyl-11b-phenyloxazolo(3,2-d)(1,4)benzodiazepin-6(5H)-one
EINECS 246-032-0
CS 300
OXAZOLAM [MART.]
OXAZOLAM [WHO-DD]
DTXSID5023401
Benzo(6,7)-1,4-diazepino-(5,4-b)-oxazol-6-one, 10-chloro-2,3,5,6,7,11b-hexahydro-2-methyl-11b-phenyl-
Oxazolamum (INN-Latin)
OXAZOLAM (MART.)
(cis,trans)-10-Chlor-2,3,5,6,7,11b-tetrahydro-2-methyl-11b-phenyloxazolo(3,2-d)(1,4)benzodiazepin-6(5H)-on
Oxazolo(3,2-d)(1,4)benzodiazepin-6(5H)-one, 10-chloro-2,3,7,11b-tetrahydro-2-methyl-11b-phenyl-
Oxazolo[3,2-d][1,4]benzodiazepin-6(5H)-one, 10-chloro-2,3,7,11b-tetrahydro-2-methyl-11b-phenyl-
Oxazolam (1.0mg/ml in Acetonitrile)
10-Chloro-2,3,7,11b-tetrahydro-2-methyl-11b-phenyloxazolo[3,2-d][1,4]benzodiazepin-6(5H)-one
UNII-1V2WI2NA1C
(2S,4R)-13-chloro-4-methyl-2-phenyl-3-oxa-6,9-diazatricyclo(8.4.0.02,6)tetradeca-1(10),8,11,13-tetraen-8-ol
(2S,4R)-13-chloro-4-methyl-2-phenyl-3-oxa-6,9-diazatricyclo[8.4.0.02,6]tetradeca-1(10),8,11,13-tetraen-8-ol
10-Chloro-2-methyl-11b-phenyl-2,3,7,11b-tetrahydro(1,3)oxazolo(3,2-d)(1,4)benzodiazepin-6(5H)-one
10-Chloro-2-methyl-11b-phenyl-2,3,7,11b-tetrahydro[1,3]oxazolo[3,2-d][1,4]benzodiazepin-6(5H)-one
13-chloro-4-methyl-2-phenyl-3-oxa-6,9-diazatricyclo(8.4.0.0^(2,6))tetradeca-1(10),11,13-trien-8-one
13-chloro-4-methyl-2-phenyl-3-oxa-6,9-diazatricyclo[8.4.0.0^{2,6}]tetradeca-1(10),11,13-trien-8-one
Serenal (TN)
Oxazolam (JP17/INN)
DEA No. 2839
CHEMBL2104805
SCHEMBL10619798
CHEBI:31944
DTXCID80209312
AKOS030242155
DB15491
10-chloro-2-methyl-11b-phenyl-2,3,5,7-tetrahydro-[1,3]oxazolo[3,2-d][1,4]benzodiazepin-6-one
D01278
10-chloro-2,3,5,11b-tetrahydro-2-methyl-11b-phenyloxazolo[3,2-d][1,4]benzodiazepin-6(7H)-one
10-chloro-2,3,7,11b-tetrahydro-2-methyl-11b-phenylbenzo(6,7)(1,4)diazepino(5,4-b) oxazol-6-one
10-Chloro-2-methyl-11b-phenyl-2,3,7,11b-tetrahydro[1,3]oxazolo[3,2-d][1,4]benzodiazepin-6(5H)-one #
246-032-0