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Flubromazepam

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Identification
Molecular formula
C15H10BrFN2O3
CAS number
2647-50-9
IUPAC name
10-bromo-11b-(2-fluorophenyl)-2,3,5,7-tetrahydrooxazolo[3,2-d][1,4]benzodiazepin-6-one
State
State

At room temperature, Flubromazepam is a solid. It is usually distributed in powdered form, primarily for use in chemical research and analysis.

Melting point (Celsius)
215.00
Melting point (Kelvin)
488.15
Boiling point (Celsius)
316.60
Boiling point (Kelvin)
589.75
General information
Molecular weight
418.15g/mol
Molar mass
418.2610g/mol
Density
1.4400g/cm3
Appearence

Flubromazepam appears as an off-white to yellow crystalline solid. It is typically available in powder form for research and analytical purposes.

Comment on solubility

Solubility of 10-bromo-11b-(2-fluorophenyl)-2,3,5,7-tetrahydrooxazolo[3,2-d][1,4]benzodiazepin-6-one

The solubility of the compound with the formula C15H10BrFN2O3 is influenced by its unique structural features and functional groups. Here are some insights into its solubility characteristics:

  • Polarity: The presence of polar functional groups such as the hydroxyl (O) and nitrogen (N) atoms often enhances solubility in polar solvents, particularly in water.
  • Halogen Effect: The bromine (Br) and fluorine (F) substituents can impact solubility. Generally, halogens can introduce some degree of hydrophobicity, which can reduce water solubility.
  • Intramolecular Interactions: The cyclic structure may lead to unique intramolecular hydrogen bonding that can affect the overall solubility behavior.
  • Solvent Type: Solubility is greatly influenced by the choice of solvent. For example, the compound may show preferable solubility in organic solvents like ethanol or acetone compared to water.

In summary, while predictions about solubility can be made based on the structural aspects, the actual solubility of C15H10BrFN2O3 can vary significantly based on environmental conditions and the presence of other solutes. Understanding these factors is crucial for practical applications of this compound.

Interesting facts

Interesting Facts about 10-bromo-11b-(2-fluorophenyl)-2,3,5,7-tetrahydrooxazolo[3,2-d][1,4]benzodiazepin-6-one

The compound 10-bromo-11b-(2-fluorophenyl)-2,3,5,7-tetrahydrooxazolo[3,2-d][1,4]benzodiazepin-6-one is a fascinating example of a complex molecular structure that showcases the interplay between different elements in organic chemistry. Here are some noteworthy facts about this intriguing compound:

  • Pharmacological Interest: Due to its structure, this compound may exhibit potential therapeutic properties, possibly in the realms of neuroscience or psychiatry where benzodiazepines are widely studied for their effects on the central nervous system.
  • Halogen Influence: The presence of bromine and fluorine atoms in the structure suggests that they could be playing a significant role in modulating the compound's reactivity and biological activity, enhancing properties such as lipophilicity or binding affinity.
  • Oxazolo[3,2-d][1,4]benzodiazepine Framework: This unique bicyclic structure is known to impart specific pharmacological characteristics, making it a subject of interest in medicinal chemistry, particularly in the search for new anxiolytic or sedative agents.
  • Types of Isomerism: The compound can exhibit stereoisomerism due to the multiple chiral centers in its skeleton, potentially leading to different biological activities for each isomer.
  • Research Potential: With ongoing advancements in drug discovery, compounds like this one are often identified as lead candidates for developing novel therapies, making them of great interest to researchers in pharmacology and medicinal chemistry.

As scientists dig deeper into the functionalities of complex organic compounds like this, they unravel the mysteries of how molecular modifications can lead to different biochemical pathways and therapeutic outcomes. The study of such compounds not only contributes to our understanding of chemistry but also opens doors to innovative treatments for various health conditions.

Synonyms
haloxazolam
Somelin
59128-97-1
Haloxazolamum
Haloxazolam [INN:JAN]
CS-430
Haloxazolamum [INN-Latin]
CS 430
Somelin (TN)
BRN 0569670
M448L2V8XP
HALOXAZOLAM [MI]
HALOXAZOLAM [INN]
HALOXAZOLAM [JAN]
HALOXAZOLAM [MART.]
HALOXAZOLAM [WHO-DD]
10-Bromo-11b-(2-fluorophenyl)-2,3,7,11b-tetrahydrooxazolo(3,2-d)(1,4)benzodiazepin-6(5H)-one
DTXSID60866740
10-Bromo-11b-(o-fluorophenyl)-2,3,7,11b-tetrahydrooxazolo(3,2-d)(1,4)benzodiazepin-6(5H)-one
Haloxazolamum (INN-Latin)
HALOXAZOLAM (MART.)
Oxazolo(3,2-d)(1,4)benzodiazepin-6(5H)-one, 2,3,7,11b-tetrahydro-10-bromo-11b-(2-fluorophenyl)-
Haloxazolam (1.0mg/ml in Acetonitrile)
Oxazolo[3,2-d](1,4)benzodiazepin-6(5H)-one, 2,3,7,11b-tetrahydro-10-bromo-11b-(2-fluorophenyl)-
DEA No. 2771
(11bRS)-10-Bromo-11b-(2-fluorophenyl)-2,3,7,11b-tetrahydro(1,3)oxazolo(3,2-d)(1,4)benzodiazepin-6(5H)-one
(11bRS)-10-Bromo-11b-(2-fluorophenyl)-2,3,7,11b-tetrahydro[1,3]oxazolo[3,2-d][1,4]benzodiazepin-6(5H)-one
10-Bromo-11b-(2-fluorophenyl)-2,3,7,11b-tetrahydrooxazolo[3,2-d](1,4)benzodiazepin-6(5H)-one
10-Bromo-11b-(o-fluorophenyl)-2,3,7,11b-tetrahydrooxazolo[3,2-d][1,4]benzodiazepin-6(5H)-one
13-bromo-2-(2-fluorophenyl)-3-oxa-6,9-diazatricyclo(8.4.0.02,?)tetradeca-1(10),11,13-trien-8-one
13-bromo-2-(2-fluorophenyl)-3-oxa-6,9-diazatricyclo(8.4.0.02,6)tetradeca-1(10),11,13-trien-8-one
13-bromo-2-(2-fluorophenyl)-3-oxa-6,9-diazatricyclo[8.4.0.02,?]tetradeca-1(10),11,13-trien-8-one
13-bromo-2-(2-fluorophenyl)-3-oxa-6,9-diazatricyclo[8.4.0.02,6]tetradeca-1(10),11,13-trien-8-one
Oxazolo[3,2-d][1,4]benzodiazepin-6(5H)-one, 10-bromo-11b-(2-fluorophenyl)-2,3,7,11b-tetrahydro-; 10-Bromo-11b-(2-fluorophenyl)-2,3,7,11b-tetrahydro[1,3]oxazolyl[3,2-d][1,4]benzodiazepin-6(5H)-one; CS 430; Haloxazolam; Somelin
Haloxazolam (JP17/INN)
UNII-M448L2V8XP
10-bromo-11b-(2-fluorophenyl)-2,3,5,7-tetrahydro-[1,3]oxazolo[3,2-d][1,4]benzodiazepin-6-one
SCHEMBL156227
CHEMBL2104461
CHEBI:31666
DTXCID90814996
XDKCGKQHVBOOHC-UHFFFAOYSA-N
DB01476
D01758
Q4345875
10-Bromo-11b-(2-fluorophenyl)-2,3,7,11b-tetrahydro[1,3]oxazolo[3,2-d][1,4]benzodiazepin-6(5H)-one #