Interesting facts
Interesting Facts About 10-[3-(4-methylpiperazin-1-yl)propyl]-2-(trifluoromethyl)phenothiazine
10-[3-(4-methylpiperazin-1-yl)propyl]-2-(trifluoromethyl)phenothiazine is a fascinating compound found in the realm of medicinal chemistry. This compound is an example of the phenothiazine class, which has been extensively studied due to its interesting therapeutic properties.
Key Highlights:
- Pharmacological Relevance: Compounds in the phenothiazine family are renowned for their antipsychotic properties. They have been utilized in the treatment of schizophrenia and various other mental health disorders.
- Structural Features: This compound showcases a unique molecular structure characterized by a trifluoromethyl group. This functional group enhances its lipophilicity, making it more effective in crossing the blood-brain barrier.
- Piperazine Derivatives: The presence of the 4-methylpiperazin-1-yl group adds to the molecular diversity and biological activity, illustrating the importance of structural modifications in drug development.
- Fluorine in Therapeutics: The inclusion of fluorine atoms is becoming increasingly common in pharmaceuticals due to their influence on metabolism and biological activity.
- Continued Research: Ongoing studies aim to explore the full potential of this compound and its derivatives, including their role in treating resistant forms of psychiatric disorders.
In summary, 10-[3-(4-methylpiperazin-1-yl)propyl]-2-(trifluoromethyl)phenothiazine not only highlights the ever-evolving field of medicinal chemistry but also emphasizes the importance of chemical innovation in addressing complex health conditions. As we advance our understanding of such compounds, the prospects for new therapies become increasingly promising.
Synonyms
trifluoperazine
117-89-5
Trifluperazine
Trifluoroperazine
Trifluoperazin
Trifluoperazina
Flurazine
Triflurin
Triperazine
Trifluoromethylperazine
Trifluoperazinum
Trifluroperizine
Apo-Trifluoperazine
Eskazine
RP 7623
10-[3-(4-methylpiperazin-1-yl)propyl]-2-(trifluoromethyl)phenothiazine
TFP
Fluoperazine
Trifluoromethyl-10-(3'-(1-methyl-4-piperazinyl)propyl)phenothiazine
Trifluoperazinum [INN-Latin]
10H-Phenothiazine, 10-[3-(4-methyl-1-piperazinyl)propyl]-2-(trifluoromethyl)-
Trifluoperazina [INN-Spanish]
CCRIS 6994
HSDB 3195
10-(3-(4-methylpiperazin-1-yl)propyl)-2-(trifluoromethyl)-10H-phenothiazine
EINECS 204-219-4
NSC 17474
NSC 46061
NSC-17474
10-(3-(4-Methyl-1-piperazinyl)propyl)-2-(trifluoromethyl)phenothiazine
10-[3-(4-methylpiperazin-1-yl)propyl]-2-(trifluoromethyl)-10H-phenothiazine
Calmazine
UNII-214IZI85K3
CHEBI:45951
Trifluoperazine (INN)
10-(gamma-(N'-Methylpiperazino)propyl)-2-trifluoromethylphenothiazine
214IZI85K3
10-[3-(4-Methyl-1-piperazinyl)propyl]-2-(trifluoromethyl)-10H-phenothiazine
10H-Phenothiazine, 10-(3-(4-methyl-1-piperazinyl)propyl)-2-(trifluoromethyl)-
NSC-46061
RP-7623
2-Trifluoromethyl-10-(3'-(1-methyl-4-piperazinyl)propyl)phenothiazine
Phenothiazine, 10-(3-(4-methyl-1-piperazinyl)propyl)-2-(trifluoromethyl)-
10-[3-(4-METHYL-PIPERAZIN-1-YL)-PROPYL]-2-TRIFLUOROMETHYL-10H-PHENOTHIAZINE
SKF 5019
Stellazine
NSC17474
10-(3-(4-methyl-1-piperazinyl)propyl)-2-(trifluoromethyl)-10H-phenothiazine
Trifluoperazina [Italian]
TRIFLUOPERAZINE [INN]
Trifluoperazinum (INN-Latin)
Trifluoperazina (INN-Spanish)
Trifluoperazine [INN:BAN]
81498-90-0
C21H24F3N3S
MLS001146870
MLS002702821
2-Trifluoromethyl-10-[3'-(1-methyl-4-piperazinyl)propyl]phenothiazine
10H-Phenothiazine,10-[3-[4-(methyl-d3)-1-piperazinyl]propyl]-2-(trifluoromethyl)-
SMR001566649
1432064-02-2
10-[3-(4-methylpiperazin-1-yl)propyl]-2-(trifluoromethyl)phenothiazine dihydrochloride
CAS-440-17-5
Apo-trifluoperazine (TN)
Stelazine (*Dihydrochloride*)
10-(3-(4-methylpiperazin-1-yl)propyl)-2-(trifluoromethyl)phenothiazine
Phenothiazine, 10-[3-(4-methyl-1-piperazinyl)propyl]-2-(trifluoromethyl)-
10-(3-(4-METHYL-PIPERAZIN-1-YL)-PROPYL)-2-TRIFLUOROMETHYL-10H-PHENOTHIAZINE
NCI17474
Synklor (Salt/Mix)
Stelazine (Salt/Mix)
Triftazin (Salt/Mix)
Spectrum_000668
Terfluzine (Salt/Mix)
Triftazine (Salt/Mix)
Jatroneural (Salt/Mix)
Fluoperazine (Salt/Mix)
Triphthazine (Salt/Mix)
Prestwick0_000313
Prestwick1_000313
Prestwick2_000313
Prestwick3_000313
Spectrum2_000828
Spectrum3_001374
Spectrum4_000368
Spectrum5_001553
Lopac-T-8516
Biomol-NT_000060
CHEMBL422
cid_5566
NCIStruc1_001127
NCIStruc2_001093
TRIFLUOPERAZINE [MI]
BIDD:PXR0132
Lopac0_001232
SCHEMBL24866
BSPBio_000306
BSPBio_001190
BSPBio_002928
GTPL214
KBioGR_000530
KBioGR_000835
KBioGR_002431
KBioSS_000530
KBioSS_001148
KBioSS_002437
MLS006011857
DivK1c_000843
TRIFLUOPERAZINE [HSDB]
SPBio_000755
SPBio_002525
TRIFLUOPERAZINE [VANDF]
BPBio1_000338
BPBio1_001345
2-TRIFLUOROMETHYL-10-
Trifluoperazine-d3 Hydrochloride
DTXSID1046928
TRIFLUOPERAZINE [WHO-DD]
BDBM79181
cid_2913535
KBio1_000843
KBio2_000530
KBio2_001148
KBio2_002431
KBio2_003098
KBio2_003716
KBio2_004999
KBio2_005666
KBio2_006284
KBio2_007567
KBio3_000959
KBio3_000960
KBio3_002148
KBio3_002910
N05AB06
cMAP_000048
NINDS_000843
Bio1_000458
Bio1_000947
Bio1_001436
Bio2_000435
Bio2_000915
HMS1362L11
HMS1792L11
HMS1990L11
HMS2089J11
HMS3429O07
KUC109776N
BCP32898
EX-A3330
HHC06402
CCG-37306
NCGC00013226
PDSP1_001300
PDSP2_001284
s5856
STK182873
10-(3-(4-methyl-1-piperazinyl)propyl)-2-(trifluoromethyl)-phenothiazine
AKOS001487920
DB00831
SDCCGSBI-0051199.P005
IDI1_000843
IDI1_002190
KSC-210-031
MRF-0000088
QTL1_000085
NCGC00013226-02
NCGC00013226-03
NCGC00013226-04
NCGC00013226-05
NCGC00013226-06
NCGC00013226-07
NCGC00013226-08
NCGC00013226-09
NCGC00013226-10
NCGC00013226-11
NCGC00013226-12
NCGC00013226-13
NCGC00013226-15
NCGC00013226-26
NCGC00013226-32
NCGC00024251-03
NCGC00024251-04
NCGC00024251-05
NCGC00024251-06
NCGC00024251-07
AC-35814
NCI60_001427
NCI60_004087
TS-09796
SBI-0051199.P003
AB00053558
NS00007413
C07168
D08636
EN300-708763
G78129
AB00053558-27
AB00053558_28
AB00053558_29
L001075
Q1752915
SR-01000003020-6
BRD-K89732114-001-02-6
BRD-K89732114-001-03-4
BRD-K89732114-001-05-9
BRD-K89732114-300-05-5
BRD-K89732114-300-07-1
BRD-K89732114-300-13-9
BRD-K89732114-300-14-7
BRD-K89732114-300-15-4
Triphthazine;Trifluperazine;NSC-17474;RP-7623;SKF-5019
10-(.gamma.-(N'-Methylpiperazino)propyl)-2-trifluoromethylphenothiozine
10-[3-(4-Methyl-1-piperazinyl)propyl]-2-(trifluoromethyl)-10H-phenothiazine #
10-[3-(4-methyl-1-piperazinyl)propyl]-2-(trifluoromethyl)phenothiazine;hydrochloride
10-[3-(4-methylpiperazino)propyl]-2-(trifluoromethyl)phenothiazine;hydrochloride
204-219-4
Solubility of 10-[3-(4-methylpiperazin-1-yl)propyl]-2-(trifluoromethyl)phenothiazine
The solubility characteristics of 10-[3-(4-methylpiperazin-1-yl)propyl]-2-(trifluoromethyl)phenothiazine (C21H24F3N3S) reveal interesting insights about this compound's behavior in different solvents. Generally, the solubility of such organic compounds can be influenced by various factors:
In practical applications, the solubility of phenothiazine derivatives can determine their bioavailability and effectiveness in pharmaceutical formulations. As a general statement, it can be observed that:
Understanding these solubility dynamics is crucial for leveraging this compound's potential in medicinal applications.