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Propranolol

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Identification
Molecular formula
C16H21NO2
CAS number
525-66-6
IUPAC name
1-(tert-butylamino)-3-(2-cyclopentylphenoxy)propan-2-ol
State
State

At room temperature, propranolol is typically found in a solid state, appearing as a crystalline solid.

Melting point (Celsius)
96.00
Melting point (Kelvin)
369.15
Boiling point (Celsius)
292.60
Boiling point (Kelvin)
565.80
General information
Molecular weight
259.36g/mol
Molar mass
259.3640g/mol
Density
1.0580g/cm3
Appearence

Propranolol is a white to off-white crystalline solid. It is odorless and tasteless.

Comment on solubility

Solubility of 1-(tert-butylamino)-3-(2-cyclopentylphenoxy)propan-2-ol (C16H21NO2)

The solubility of 1-(tert-butylamino)-3-(2-cyclopentylphenoxy)propan-2-ol in various solvents is crucial for its applications in pharmaceutical formulations and chemical synthesis. Several factors influence its solubility, including:

  • Molecular Structure: The presence of the tert-butylamino group may impart some degree of hydrophilicity, while the cyclopentylphenoxy moiety introduces hydrophobic characteristics.
  • Solvent Polarity: Generally, compounds with both polar and non-polar regions tend to be more soluble in polar-apolar solvent mixtures. This compound might exhibit moderate solubility in solvents such as ethanol or methanol and lower solubility in non-polar solvents like hexane.
  • Temperature Effects: Increased temperature may enhance solubility for certain compounds, particularly if dissolution is endothermic. Thus, temperature adjustments can be beneficial in optimizing the solubility of this compound.

In practical use, solubility tests would likely reveal that:

  1. The compound may dissolve adequately in polar organic solvents.
  2. It might have limited solubility in water, indicating the need for co-solvents or solubilizers during formulation.

Understanding these aspects of solubility allows chemists to effectively utilize 1-(tert-butylamino)-3-(2-cyclopentylphenoxy)propan-2-ol in various applications, maximizing its potential in research and development.

Interesting facts

Interesting Facts About 1-(tert-butylamino)-3-(2-cyclopentylphenoxy)propan-2-ol

1-(tert-butylamino)-3-(2-cyclopentylphenoxy)propan-2-ol is a fascinating compound that has garnered interest in various scientific domains. Here are some engaging aspects about its structure and potential applications:

  • Complex Structure: The compound features a unique arrangement that incorporates both an amino group and a phenoxy group. This combination allows for interesting interactions with biological systems, making it valuable for pharmacological studies.
  • Pharmacological Potential: Compounds with similar structures have been investigated for their activity as beta-adrenergic antagonists or other therapeutic agents. This suggests that 1-(tert-butylamino)-3-(2-cyclopentylphenoxy)propan-2-ol might have potential applications in treating conditions such as hypertension.
  • Versatile Applications: Its distinctive moieties may also play a role in the development of selective receptor modulators, which can fine-tune biological responses.
  • Research Significance: As scientists explore various ligand-receptor interactions, compounds like this could pave the way for new drug discovery and development, highlighting the importance of chemical diversity in medicinal chemistry.

The study of such compounds not only advances our understanding of chemistry but also leads to potentially life-saving medicinal applications. As researchers continue to unravel the complexities of compounds like 1-(tert-butylamino)-3-(2-cyclopentylphenoxy)propan-2-ol, the possibilities for innovations in healthcare are boundless.

Synonyms
36507-48-9
rac Penbutolol
1-(tert-butylamino)-3-(2-cyclopentylphenoxy)propan-2-ol
1-(tert-Butylamino)-3-(o-cyclopentylphenoxy)propan-2-ol
112160-87-9
1-(2-Cyclopentylphenoxy)-3-[(1,1-dimethylethyl)amino]-2-propanol
(S)-Penbutolol;(-)-Isopenbutolol
rac-Penbutolol; 2-Propanol, 1-(2-cyclopentylphenoxy)-3-[(1,1-dimethylethyl)amino]-; (+/-)-Isopenbutolol; (+/-)-Penbutolol
(+/-)-Penbutolol
(+/-)-Isopenbutolol
PENBUTOLOL(-)
Prestwick0_001043
Prestwick1_001043
Prestwick2_001043
Prestwick3_001043
Penbutolol, (+/-)-
3JET4HND2G
SCHEMBL49358
BSPBio_000966
CHEMBL26362
SPBio_002903
BPBio1_001064
BDBM82364
DTXSID10860556
KQXKVJAGOJTNJS-UHFFFAOYSA-N
LBA50748
NBA36341
NSC_37464
1ST1324
SB82073
NCGC00179359-04
CAS_38363-40-5
AB00514016
NS00089781
L013431