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1-tert-butyl-3-(1-naphthyl)pyrazolo[3,4-d]pyrimidin-4-amine

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Identification
Molecular formula
C20H20N4
CAS number
210481-21-7
IUPAC name
1-tert-butyl-3-(1-naphthyl)pyrazolo[3,4-d]pyrimidin-4-amine
State
State

This compound is typically a powder at room temperature.

Melting point (Celsius)
218.00
Melting point (Kelvin)
491.00
Boiling point (Celsius)
495.85
Boiling point (Kelvin)
769.00
General information
Molecular weight
325.40g/mol
Molar mass
325.3850g/mol
Density
1.2400g/cm3
Appearence

The compound typically appears as a white to off-white crystalline powder.

Comment on solubility

Solubility of 1-tert-butyl-3-(1-naphthyl)pyrazolo[3,4-d]pyrimidin-4-amine

The solubility of 1-tert-butyl-3-(1-naphthyl)pyrazolo[3,4-d]pyrimidin-4-amine (C20H20N4) can be quite complex due to its structural characteristics. The compound features multiple aromatic rings and a tert-butyl group, which will influence its interaction with solvents.

Here are some insightful points regarding solubility:

  • Hydrophilicity vs. Hydrophobicity: This compound is largely hydrophobic due to the presence of the bulky tert-butyl and naphthyl groups, making it less soluble in water.
  • Common Solvents: It is expected to dissolve more effectively in organic solvents such as dimethyl sulfoxide (DMSO), ethanol, or chloroform due to its hydrophobic nature.
  • Temperature Effects: Solubility can increase with temperature, often leading to greater dissolution in organic media as the kinetic energy of the molecules increases.

In conclusion, while 1-tert-butyl-3-(1-naphthyl)pyrazolo[3,4-d]pyrimidin-4-amine may exhibit limited solubility in aqueous environments, its affinity for non-polar solvents highlights its distinctive chemical profile. Understanding these solubility characteristics is crucial for applications in research and pharmaceuticals.

Interesting facts

Exploring 1-tert-butyl-3-(1-naphthyl)pyrazolo[3,4-d]pyrimidin-4-amine

1-tert-butyl-3-(1-naphthyl)pyrazolo[3,4-d]pyrimidin-4-amine is a fascinating compound that belongs to the class of pyrazolo[3,4-d]pyrimidines. This compound has garnered interest in the field of medicinal chemistry due to its promising biological activities. Here are some intriguing facts about this compound:

  • Structural Complexity: The molecule's structure is an impressive amalgamation of a pyrazolo and pyrimidine ring system combined with a 1-naphthyl group. This intricate setup not only contributes to its unique characteristics but also influences its pharmacological activities.
  • Biological Importance: Compounds similar to 1-tert-butyl-3-(1-naphthyl)pyrazolo[3,4-d]pyrimidin-4-amine have been studied for their potential anti-cancer properties. Researchers have noted that they may inhibit specific enzyme targets involved in tumor proliferation.
  • Receptor Modulation: This compound has been observed to interact with various biological receptors, which suggests its potential as a lead compound in drug development. It's crucial for researchers to explore these interactions to fully understand its therapeutic applications.
  • Analytical Significance: The unique structure of this compound makes it an ideal candidate for advanced analytical techniques such as NMR and mass spectrometry, which help elucidate its behavior in different environments.
  • Research Outlook: As drug design continues to evolve, 1-tert-butyl-3-(1-naphthyl)pyrazolo[3,4-d]pyrimidin-4-amine stands as a reminder of the intricate relationships between molecular structure and biological activity. Ongoing studies may reveal even more exciting uses in therapeutic applications.

In summary, 1-tert-butyl-3-(1-naphthyl)pyrazolo[3,4-d]pyrimidin-4-amine encapsulates the complexity of modern medicinal chemistry. Its multifaceted nature makes it a compound worth exploring further, both for its structural properties and potential therapeutic benefits.

Synonyms
221243-82-9
1-NAPHTHYL PP1
1-NA-PP1
1-(tert-Butyl)-3-(naphthalen-1-yl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine
4-Amino-1-tert-butyl-3-(1'-naphthyl)pyrazolo[3,4-d]pyrimidine
1-tert-butyl-3-naphthalen-1-ylpyrazolo[3,4-d]pyrimidin-4-amine
1-(1,1-dimethylethyl)-3-(1-naphthalenyl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine
C19H19N5
1-tert-butyl-3-(naphthalen-1-yl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine
CHEMBL264406
CHEBI:52310
1-tert-butyl-3-naphthalen-1-yl-1H-pyrazolo[3,4-d]pyrimidin-4-amine
1-TERT-BUTYL-3-(NAPHTHALEN-1-YL)PYRAZOLO[3,4-D]PYRIMIDIN-4-AMINE
4gkh
0J9
1-naphthyl-PP1
MFCD03425471
K00047
SCHEMBL173288
1-NA-PP1?
1-Naphthyl PP1(1-NA-PP1)
DTXSID00274446
EX-A867
XSHQBIXMLULFEV-UHFFFAOYSA-N
HMS3266C18
HMS3413H14
HMS3677H14
PP1-AG1872
BCP09108
1-tert-butyl-3-naphthalen-1-yl-1H-pyrazolo[3,4-d]pyrimidin-4-ylamine
BDBM50229961
HB0066
s2642
AKOS024457409
CS-1804
MB02817
SDCCGSBI-0654254.P001
NCGC00262627-06
AS-56537
HY-13941
PD012665
DB-249967
F17431
BRD-K29542628-001-01-3
BRD-K29542628-001-03-9
BRD-K29542628-001-04-7
Q27123369
Z2216885141
1-t-butyl-3-naphthalen-1-yl-1h-pyrazolo[3,4-d]pyrimidin-4-ylamine
4-Amino-1-tert-butyl-3-(1''-naphthyl)pyrazolo[3,4-d]pyrimidine
4-Amino-1-tert-butyl-3-(1?-naphthyl)pyrazolo[3,4-d]pyrimidine
1-(tert-butyl)-3-(naphthalen-1-yl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine (4)
1H-pyrazolo[3,4-d]pyrimidin-4-amine, 1-(1,1-dimethylethyl)-3-(1-naphthalenyl)-
1H-Pyrazolo[3,4-d]pyrimidin-4-amine, 1-(1,1-dimethylethyl)-3-(1-naphthalenyl)- (9CI)
4-Amino-1-tert-butyl-3-(1 inverted exclamation mark -naphthyl)pyrazolo[3,4-d]pyrimidine
9-naphthalen-1-yl-7-tert-butyl-3,5,7,8-tetrazabicyclo[4.3.0]nona-1,3,5,8-tetraen-2-amine