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Amphetamine sulfate

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Identification
Molecular formula
(C9H13N)2·H2SO4
CAS number
60-13-9
IUPAC name
1-phenylpropan-2-amine;sulfuric acid
State
State

At room temperature, amphetamine sulfate is found in a solid state. It is stable under normal conditions but should be stored properly to prevent degradation.

Melting point (Celsius)
280.00
Melting point (Kelvin)
553.15
Boiling point (Celsius)
302.00
Boiling point (Kelvin)
575.15
General information
Molecular weight
368.50g/mol
Molar mass
368.4970g/mol
Density
1.2000g/cm3
Appearence

Amphetamine sulfate appears as a white or off-white crystalline powder. It is often odorless and has a slightly bitter taste. Due to its structure, it may appear slightly opaque or transparent depending on the granulation size.

Comment on solubility

Solubility of 1-phenylpropan-2-amine sulfate

1-phenylpropan-2-amine sulfate, represented by the chemical formula (C9H13N)2·H2SO4, exhibits notable solubility traits that are essential for its applications in chemical processes.

Solubility Characteristics:

  • Water Solubility: This compound is typically soluble in water, largely due to the presence of the sulfate group, which can ionize and interact favorably with water molecules.
  • Temperature Influence: Solubility may increase with temperature, which is a common trait among many sulfate salts.
  • Polarity Effects: The amine functionality contributes to the polarity of the molecule, enhancing its affinity for polar solvents like water.
  • Organic Solvents: 1-phenylpropan-2-amine sulfate may have moderate solubility in organic solvents, but this can be highly solvent-dependent.

In general, the solubility of 1-phenylpropan-2-amine sulfate in aqueous solutions can be described as favorable due to its ionic nature, allowing it to dissociate and engage in various chemical reactions. Understanding these solubility properties is crucial for researchers and industry professionals who utilize this compound in pharmacological and synthesis applications.

Overall, the interplay of functional groups and the influence of solvent characteristics play a significant role in determining the solubility of this compound.

Interesting facts

Interesting Facts about 1-Phenylpropan-2-amine Sulfuric Acid

1-Phenylpropan-2-amine, often referred to as amphetamine, is a fascinating compound with a rich history in both medicinal and recreational contexts. When combined with sulfuric acid, it forms a salt that can be used in various applications such as pharmaceuticals and research.

Key Points of Interest:

  • Therapeutic Use: Amphetamines are primarily known for their use in treating attention deficit hyperactivity disorder (ADHD) and narcolepsy. They work by increasing the levels of certain neurotransmitters in the brain, primarily dopamine and norepinephrine.
  • Potential for Misuse: Due to their stimulating effects, amphetamines have a history of recreational use, which can lead to dependency and misuse. Regulations surrounding their prescription are stringent in many countries.
  • Experimental Applications: Beyond therapeutic uses, 1-phenylpropan-2-amine compounds are often subjected to research in neuropharmacology. They are explored for their potential in treating various psychiatric disorders.
  • Research in Chemistry: Scientists often study the reactions of amphetamines to understand their properties better and to develop new compounds that may offer improved therapeutic outcomes.

As with many chemical compounds, the effects and applications of 1-phenylpropan-2-amine extend beyond simple characterization. It epitomizes the intersection of chemistry, medicine, and ethics, providing a rich ground for discussion and inquiry. As one researcher aptly put it, "The beauty of chemistry lies in its ability to unravel complex interactions that can profoundly impact human lives."

Continued research and responsible usage of compounds like 1-phenylpropan-2-amine are essential to harnessing their benefits while minimizing risks. Scientists and medical practitioners must navigate the delicate balance between the therapeutic potential and the possibility of abuse.

Synonyms
DL-Amphetamine sulfate
60-13-9
Phenaminum
Astedin
Amphetamine sulphate
Amphamine sulfate
Amphetamini sulfas
Benzpropamine
Pharmamedrine
Psychedrinum
Synsatedrine
Adiparthrol
Aktedrin
Benzafinyl
Betaphen
Bluzedrin
Cartwheels
Dietamine
Durophet
Euphobine
Euphodine
Euphodyn
Fabedrine
Fenedrin
Ibiozedrine
Mimetina
Monetamine
Oraldrina
Phenpromin
Psychedryna
Psychoton
Racephen
Simpamina
Simpamine
Sympametin
Theptine
Vapedrine
Alentol
Bennie
Benzies
Betafen
Fenara
Leodrin
Noclon
Peaches
Sedolin
Zedrine
Anara
dl-Phenamine sulfate
Roses
Halloo-Wach
Amphoids-S
Phenamine sulfate
dl-Amphetamine sulphate
Amfetamine sulfate
Amphetaminium sulfuricum
Benzedrine sulfate
Fenopromin sulfate
Desoxynorephedrine sulfate
DL-Amphetamine hydrogen sulfate
Phenisopropylamine sulfate
(+-)-Phenisopropylamine sulfate
(+-)-Amphetamine sulfate
Phenamine (sympathomimetic)
DL-1-Phenyl-2-aminopropane sulfate
CCRIS 3644
(+-)-2-Amino-1-phenylpropane sulfate
1-Phenyl-2-aminopropane sulfate
CERM 1767
Razemisches phenylaminopropansulfat
NCI-C55710
UNII-6DPV8NK46S
Amphetamine sulfate [USP]
Amfetamine sulphate
dl-alpha-Methylphenethylamine sulfate
EINECS 200-457-8
6DPV8NK46S
NSC 170999
(+-)-alpha-Methylphenethylamine sulfate (2:1)
EVEKEO ODT
alpha-Methylphenethylamine sulfate, (+-)-
Amphetamine sulfate (USP)
Dextroamphetamine sulfate
DTXSID4020082
CHEBI:51063
1-phenylpropan-2-amine;sulfuric acid
Phenethylamine, alpha-methyl-, sulfate (2:1), (+-)-
1-phenylpropan-2-amine sulfate (2:1)
Benzeneethanamine, alpha-methyl-, sulfate
d,l-Amphetamine.sulfate
DELCOBESE COMPONENT AMPHETAMINE SULFATE
(+/-)-2-AMINO-1-PHENYLPROPANE SULFATE
(+/-)-2-AMINO-1-PHENYLPROPANE SULPHATE
Penamine (VAN)
AMFETAMINE SULFATE (MART.)
AMFETAMINE SULFATE [MART.]
bis(1-phenylpropan-2-amine) sulfate
bis{1-phenylpropan-2-amine} sulfate
AMFETAMINE SULFATE (EP IMPURITY)
AMFETAMINE SULFATE [EP IMPURITY]
AMFETAMINE SULFATE (EP MONOGRAPH)
AMFETAMINE SULFATE [EP MONOGRAPH]
AMPHETAMINE SULFATE (USP MONOGRAPH)
AMPHETAMINE SULFATE [USP MONOGRAPH]
DL-Amphetamine sulfate salt
Benzadrine
Evekeo
Benzedrine (TN)
Evekeo (TN)
Sulfate, Amphetamine
ACETDRON
CENTRAMINE
rac-Amphetamine Sulphate
D-Amphetamine sulfate salt
Amphetamine Sulfate Tablets
DTXCID2082
Amphetamine Sulfate (2:1)
SCHEMBL41204
AMPHETAMINE SULFATE [MI]
PYHRZPFZZDCOPH-UHFFFAOYSA-N
AMPHETAMINE SULFATE [VANDF]
AMFETAMINE SULFATE [WHO-DD]
beta-PHENYLISOPYROPYLAMINESULFATE
AMPHETAMINE SULFATE [ORANGE BOOK]
.BETA.-PHENYLISOPYROPYLAMINESULFATE
156-31-0
AMFETAMINE SULFATE [INCB:GREEN LIST]
NS00076291
D02074
AMPHETAMINE SULFATE COMPONENT OF DELCOBESE
(+/-)-Alpha-Methylphenethylamine Sulfate (2:1)
ALPHA-METHYLBENZENEETHANAMINE SULFATE (2:1)
Q21270844
(+/-)-alpha-METHYLPHENETHYLAMINE SULPHATE (2:1)
(+/-)-.ALPHA.-METHYLPHENETHYLAMINE SULFATE (2:1)
(+/-)-.ALPHA.-METHYLPHENETHYLAMINE SULPHATE (2:1)
d,l-Amphetamine.sulfate, 1mg/ml in Methanol (as free base)
Benzeneethanamine, Alpha-Methyl-, Sulphate (2:1), (+/-)-
BENZENEETHANAMINE, ALPHA-METHYL-, (+-)-, SULFATE (2:1)
BENZENEETHANAMINE, alpha-METHYL-, SULFATE (2:1), (+/-)-
BENZENEETHANAMINE, .ALPHA.-METHYL-, SULFATE (2:1), (+/-)-
BENZENEETHANAMINE, .ALPHA.-METHYL-, SULPHATE (2:1), (+/-)-
200-457-8