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Phenelzine

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Identification
Molecular formula
C8H12N2
CAS number
51-71-8
IUPAC name
1-phenylethylhydrazine
State
State

At room temperature, Phenelzine is typically in a solid state.

Melting point (Celsius)
131.00
Melting point (Kelvin)
404.15
Boiling point (Celsius)
308.60
Boiling point (Kelvin)
581.80
General information
Molecular weight
136.19g/mol
Molar mass
136.1940g/mol
Density
1.1016g/cm3
Appearence

Phenelzine is a white to off-white crystalline powder. It is sparingly soluble in water and slightly soluble in alcohol. Its appearance might vary slightly depending upon purity and specific form.

Comment on solubility

Solubility of 1-phenylethylhydrazine

1-phenylethylhydrazine (C8H12N2) exhibits interesting solubility characteristics due to its hydrophobic phenyl group combined with the hydrazine functional group. When it comes to solubility, consider the following points:

  • Solvent Interaction: This compound is generally more soluble in organic solvents such as ethanol, dichloromethane, and acetone, rather than in water.
  • Hydrophobic vs Hydrophilic: The presence of the phenyl group enhances its hydrophobic nature, making it less likely to interact favorably with polar solvents like water.
  • Temperature Dependence: The solubility of 1-phenylethylhydrazine may increase with temperature, which is a common trend among many organic compounds.
  • Practical Implications: When handling or using this compound in laboratory settings, it will be crucial to choose the right solvent to ensure the desired concentration is achieved.

In summary, 1-phenylethylhydrazine is more soluble in non-polar solvents, and researchers should take care to select the appropriate solvation medium for reactions and applications involving this compound.

Interesting facts

Interesting Facts About 1-Phenylethylhydrazine

1-Phenylethylhydrazine is a fascinating compound that has captured the interest of both chemists and biochemists due to its unique structure and versatile applications. Here are some intriguing aspects of this compound:

  • Chemical Structure: The compound features a phenyl group attached to an ethylhydrazine moiety, showcasing a connectivity that can lead to a variety of chemical reactions. The presence of the hydrazine functional group contributes to its reactivity.
  • Biological Implications: Researchers have noted the significance of hydrazine derivatives, including 1-phenylethylhydrazine, in medicinal chemistry. For example, certain derivatives have been investigated for their potential antitumor and antimicrobial properties.
  • Synthetic Utility: This compound serves as an intermediate in the synthesis of other valuable chemicals. Its ability to participate in various reactions makes it a useful building block in organic synthesis.
  • Reactivity and Stability: The presence of the hydrazine functional group can lead to interesting chemical behavior, such as the possibility of forming diazo compounds. Care must be taken, as some hydrazines are known to be toxic and require proper handling procedures.
  • Environmental Considerations: Researchers are also examining the environmental impact of hydrazine derivatives, given their potential use and application in various fields like agrochemicals and pharmaceuticals.

In summary, 1-phenylethylhydrazine is not only a compound of interest due to its chemical properties but also for its applications in biological and synthetic chemistry. Its potential for further research remains an enticing topic for both students and seasoned chemists alike!

Synonyms
Mebanazine
(1-Phenylethyl)hydrazine
65-64-5
Actamol
Actomol
Mebanazina
1-phenylethylhydrazine
1-(1-PHENYLETHYL)HYDRAZINE
Mebanazinum
Hydrazine, (1-phenylethyl)-
Mebanazine [INN:BAN]
Mebanazinum [INN-Latin]
Mebanazina [INN-Spanish]
(alpha-Methylbenzyl)hydrazine
EINECS 200-615-6
Mebenazine
alpha-Methylbenzylhydrazine
Z5R55CJ4CG
MEBANAZINE [INN]
MEBANAZINE [MART.]
HYDRAZINE, (alpha-METHYLBENZYL)-
MEBANAZINE [WHO-DD]
29248-55-3
DTXSID50859848
.ALPHA.-METHYLBENZYLHYDRAZINE
Mebanazinum (INN-Latin)
Mebanazina (INN-Spanish)
MEBANAZINE (MART.)
1-Phenylethylhydrazine (Mebanazine) Hydrochloride
UNII-Z5R55CJ4CG
(?-Methylbenzyl)hydrazine; (?-Methylbenzyl)hydrazine Hydrochloride; Actamol Hydrochloride
30681-37-9
(1-phenyl-ethyl)-hydrazine
SCHEMBL182461
CHEMBL1909283
DTXCID70197294
CHEBI:134728
1-Phenylethylhydrazine (Mebanazine)
Hydrazine, (1-phenylethyl)-(9CI)
AKOS000161710
DB09248
DA-55308
HY-148145
CS-0613706
NS00041030
EN300-58476
SR-01000944976
SR-01000944976-1
Q10950142
200-615-6