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1-methylpicolinic acid

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Identification
Molecular formula
C7H7NO2
CAS number
2744-61-6
IUPAC name
1-methylpyridin-1-ium-2-carboxylic acid
State
State

At room temperature, 1-methylpicolinic acid is generally found in a solid state.

Melting point (Celsius)
299.00
Melting point (Kelvin)
572.15
Boiling point (Celsius)
491.00
Boiling point (Kelvin)
764.15
General information
Molecular weight
137.13g/mol
Molar mass
137.1340g/mol
Density
1.3300g/cm3
Appearence

1-Methylpicolinic acid usually appears as a white to off-white crystalline solid.

Comment on solubility

Solubility of 1-methylpyridin-1-ium-2-carboxylic acid

1-methylpyridin-1-ium-2-carboxylic acid (C7H7NO2), often referred to in discussions of solubility due to its ionic character, exhibits interesting solubility properties:

  • Water Solubility: This compound is generally soluble in water, which can be attributed to its carboxylic acid functionality that promotes hydrogen bonding with water molecules.
  • Polar Solvents: It shows good solubility in polar organic solvents, such as alcohols and acetone, due to similar interactions that mimic those in aqueous solutions.
  • Non-Polar Solvents: Conversely, 1-methylpyridin-1-ium-2-carboxylic acid is poorly soluble in non-polar solvents, reflecting the concept that “like dissolves like.”

As noted by researchers, "the interplay of ionic and molecular interactions in solution plays a crucial role in determining solubility." Therefore, the presence of both the pyridinium ion and the carboxylate group significantly enhances its solubility in various mediums.

In summary, the solubility of 1-methylpyridin-1-ium-2-carboxylic acid highlights important concepts of chemical interactions:

  • High solubility in water and polar solvents
  • Low solubility in non-polar solvents

This behavior is essential for its applications in chemical reactions and formulations where solubility plays a key role in effectiveness.

Interesting facts

Interesting Facts about 1-Methylpyridin-1-ium-2-carboxylic Acid

1-Methylpyridin-1-ium-2-carboxylic acid, a fascinating compound with a complex structure, is a derivative of pyridine, a well-known aromatic heterocycle. Here are some intriguing aspects of this compound:

  • Protonation Properties: The presence of a carboxylic acid group provides this compound with acidic properties, allowing it to participate in proton transfer reactions. This can make it valuable in various chemical processes.
  • Biological Relevance: Pyridine and its derivatives play significant roles in pharmaceuticals and biochemistry. They are often involved in the synthesis of biologically active compounds and can exhibit antibacterial and antifungal properties.
  • Intermolecular Interactions: The structure of 1-methylpyridin-1-ium-2-carboxylic acid allows for strong hydrogen bonding capabilities. This can affect its solubility and reactivity, making it an interesting subject for studies in molecular interactions.
  • Electrochemistry: As an ionic compound, 1-methylpyridin-1-ium can engage in various electrochemical reactions. Such properties are exploited in the development of sensors and electrodes that are utilized in different scientific fields.
  • Reaction Pathways: The unique structure of this compound can lead to diverse reaction pathways, which can be utilized in synthetic organic chemistry. Understanding these pathways is crucial for the development of new compounds in materials science and drug development.

Overall, 1-methylpyridin-1-ium-2-carboxylic acid showcases the incredible versatility found in heterocyclic compounds. Its ability to participate in various reactions and interactions makes it an appealing topic for both chemists and those interested in the biological implications of such compounds.

Synonyms
2-carboxy-1-methylpyridinium
SCHEMBL13113036
STL483769