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1-Methylindolin-2-one

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Identification
Molecular formula
C9H9NO
CAS number
901-53-7
IUPAC name
1-methylindolin-2-one
State
State

At room temperature, 1-Methylindolin-2-one is typically found as a solid. It is usually stable under normal conditions, but should be handled with care.

Melting point (Celsius)
140.00
Melting point (Kelvin)
413.15
Boiling point (Celsius)
348.00
Boiling point (Kelvin)
621.15
General information
Molecular weight
147.18g/mol
Molar mass
147.1790g/mol
Density
1.1620g/cm3
Appearence

1-Methylindolin-2-one is a white to off-white crystalline solid. It may appear slightly yellow due to impurities and should be stored in a dark, cool place to prevent any degradation.

Comment on solubility

Solubility of 1-Methylindolin-2-one

1-Methylindolin-2-one (C9H9NO) displays interesting solubility properties that can be influenced by factors such as polarity, temperature, and solvent type. Here’s a breakdown of its solubility characteristics:

  • Polar Solvents: 1-Methylindolin-2-one has limited solubility in polar solvents due to its relatively non-polar structure, which can be attributed to the indole moiety.
  • Non-Polar Solvents: It tends to be more soluble in non-polar organic solvents, such as chloroform and ether, which can effectively dissolve it.
  • Temperature Dependency: As with many organic compounds, increasing the temperature may enhance its solubility in organic solvents.

It's important to note that solubility can also be affected by the presence of functional groups in the solvent or the compound itself. Thus, while the solubility of 1-methylindolin-2-one might be moderate in specific solvents, “the interaction with other molecules plays a crucial role in defining solubility”. Always consider conducting preliminary solubility tests to grasp the compound’s behavior in various conditions.

Interesting facts

Interesting Facts about 1-Methylindolin-2-one

1-Methylindolin-2-one is a fascinating compound with applications that often intrigue both chemists and researchers alike. Here are some interesting points about this compound:

  • Structure and Significance: The structure of 1-methylindolin-2-one features a unique bicyclic framework that makes it an essential building block in the design of various organic molecules. Its indole-like moiety is common in many natural products and pharmaceuticals.
  • Pharmaceutical Applications: This compound has been studied for its potential use in medicinal chemistry. Various derivatives of 1-methylindolin-2-one have shown promising activity in treating diseases such as cancer and neurological disorders. Researchers are continuously investigating its therapeutic properties.
  • Dyes and Pigments: 1-Methylindolin-2-one is also known for its utility as a dye or pigment in organic synthesis, providing vibrant colors in applications including inks and coatings. Its ability to absorb light at specific wavelengths makes it useful in these industries.
  • Research Interest: As a compound within the class of indoles, 1-methylindolin-2-one continues to be a subject of significant interest in chemical research. Scientists study its reactivity, interactions, and potential transformations to expand its application range.

As a chemical entity with rich potential, studying 1-methylindolin-2-one offers insights into both fundamental and applied sciences. Its presence in naturally occurring substances and synthetic routes highlights the vast possibilities within the field of organic chemistry. As one researcher aptly put it, "The beauty of chemistry lies in the simplicity and complexity of compounds like 1-methylindolin-2-one." Embracing this compound opens a door to numerous future discoveries!

Synonyms
61-70-1
1-methylindolin-2-one
1-Methyl-2-indolinone
1-Methyl-2-oxindole
1-Methyloxindole
N-Methyloxindole
2-INDOLINONE, 1-METHYL-
N-Methyl-2-indolinone
N-Methylindol-2(3H)-one
1-methyl-3H-indol-2-one
1-Methylindol-2(3H)-one
Oxindole, 1-methyl-
1-Methyl-1,3-dihydro-2H-indol-2-one
2H-Indol-2-one, 1,3-dihydro-1-methyl-
N-Methyl-2-oxindole
BA 2777
1,3-Dihydro-1-methyl-2H-indol-2-one
1-Methyl-2-indolone
NSC 97219
BKN6HNS2AW
1-Methyl-1,3-dihydroindol-2-one
BRN 0124173
1-methyl-2,3-dihydro-1H-indol-2-one
1-Methyl-2-oxindole (1-Methyl-2-indolone)
1-Methyl-1,3-dihydro-indol-2-one
MFCD00030253
NSC-97219
DTXSID60209850
5-21-08-00008 (Beilstein Handbook Reference)
NSC97219
1-METHYL-1H-INDOLIN-2-ONE
BA-2777
N-methylindolin-2-one
UNII-BKN6HNS2AW
Oxindole, 1-methyl-(6CI)
CHEMBL41326
SCHEMBL578262
1-Methyl-2-oxindole, 97%
RSQUAQMIGSMNNE-UHFFFAOYSA-
DTXCID10132341
methyl-1,3-dihydro-indol-2-one
WLZ3260
HMS1578E04
AAA06170
STL260057
AKOS000359704
2H-Indol-2-one,3-dihydro-1-methyl-
CS-W013308
SB66124
AC-14400
CS-10396
PD179599
SY042826
TS-01920
1-Methyl-1,3-dihydro-2H-indol-2-one #
DB-025631
NS00010288
EN300-17172
2H-Indol-2-one, 1,3-dihydro-1-methyl-(9CI)
Z56899025
InChI=1/C9H9NO/c1-10-8-5-3-2-4-7(8)6-9(10)11/h2-5H,6H2,1H3
612-193-4