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(1-Methylindol-3-yl)-(4,5,6,7-tetrahydro-3H-benzimidazol-5-yl)methanone

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Identification
Molecular formula
C17H18N3O
CAS number
.
IUPAC name
(1-methylindol-3-yl)-(4,5,6,7-tetrahydro-3H-benzimidazol-5-yl)methanone
State
State

The compound is typically a crystalline solid at room temperature, with a stable structure under standard conditions.

Melting point (Celsius)
123.00
Melting point (Kelvin)
396.00
Boiling point (Celsius)
525.00
Boiling point (Kelvin)
798.00
General information
Molecular weight
266.35g/mol
Molar mass
266.3470g/mol
Density
1.3000g/cm3
Appearence

This compound typically appears as a crystalline solid with a pale yellow to off-white color. It is usually found in powder or crystal form.

Comment on solubility

Solubility Overview

The compound (1-methylindol-3-yl)-(4,5,6,7-tetrahydro-3H-benzimidazol-5-yl)methanone, with the chemical formula C17H18N3O, presents intriguing solubility characteristics due to its complex molecular structure. Understanding solubility is crucial as it influences the compound's applications in pharmaceuticals and chemical processes.

Key Solubility Insights

When assessing the solubility of this compound:

  • Polarity: The presence of both nitrogen and oxygen in the molecular structure enhances hydrogen bonding capabilities, suggesting potential solubility in polar solvents.
  • Non-polar Interactions: The indole and benzimidazole rings contribute to hydrophobic interactions, which may lead to limited solubility in highly polar solvents.
  • Solvent Compatibility: It is likely to show increased solubility in solvents such as dimethyl sulfoxide (DMSO) or ethanol, while exhibiting lower solubility in water.

Ultimately, empirical testing is essential for accurate predictions, as the solubility can vary significantly based on factors such as temperature and solvent mixture. Understanding these aspects can greatly aid in the effective application of this compound in various chemical and pharmaceutical domains.

Interesting facts

Interesting Facts about (1-methylindol-3-yl)-(4,5,6,7-tetrahydro-3H-benzimidazol-5-yl)methanone

This compound, with its intricate structure, presents a fascinating topic of study within the chemical sciences. Below are some noteworthy points about this unique compound:

  • Complex Structure: The compound features a combination of an indole moiety and a benzimidazole ring. This dual structural composition plays a significant role in its chemical behavior and potential applications.
  • Biological Relevance: Compounds with indole and benzimidazole frameworks have shown various biological activities, including antimicrobial, antiviral, and anticancer properties. This makes such compounds of keen interest in medicinal chemistry.
  • Pharmacophore Development: The combination of these two ring systems in this compound provides a novel scaffold that can be modified to create new drugs. The design of compounds like this is crucial in the fields of drug discovery and development.
  • Synthetic Routes: The synthesis of such compounds can involve multiple steps, often requiring advanced organic chemistry techniques. Understanding the synthetic pathways is essential for researchers who want to improve yields or create analogs.
  • Potential Applications: Given the properties associated with related compounds, this compound may have potential applications in pharmaceuticals. Its efficacy and safety would need to be evaluated through meticulous research and clinical trials.

As stated by many in the field, "The beauty of chemistry lies in the unexpected relationships between structure and activity." The study of (1-methylindol-3-yl)-(4,5,6,7-tetrahydro-3H-benzimidazol-5-yl)methanone and other related compounds exemplifies this philosophy, weaving together complexity and utility in the realm of chemical research.

Synonyms
132036-39-6
(1-methyl-1H-indol-3-yl)(4,5,6,7-tetrahydro-1H-benzo[d]imidazol-6-yl)methanone
5-[(1-Methylindole-3-yl)carbonyl]-4,5,6,7-tetrahydro-1H-bezimidazole
(1-methylindol-3-yl)-(4,5,6,7-tetrahydro-3H-benzimidazol-5-yl)methanone
6-(1-methyl-1H-indole-3-carbonyl)-4,5,6,7-tetrahydro-1H-1,3-benzodiazole
NTHPAPBPFQJABD-UHFFFAOYSA-N
CHEMBL325422
SCHEMBL2021739
DTXSID20861317
ZINC00004624
AKOS015896002
AC-6375
SB19072
FM148522
DB-306380
5-[(1-methylindol-3-yl)carbonyl]-4,5,6,7-tetrahydrobenzimidazole
5-[(1-Methylindole-3yl)carbonyl]4,5,6,7-tetrahydrobenzimidazole
(1-Methyl-1H-indol-3-yl)(4,5,6,7-tetrahydro-1H-benzimidazol-5-yl)methanone