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1-Methylimidazole

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Identification
Molecular formula
C4H6N2
CAS number
616-47-7
IUPAC name
1-methylimidazole
State
State

At room temperature, 1-Methylimidazole is in a liquid state. It is typically handled in liquid form for various industrial and laboratory applications.

Melting point (Celsius)
-60.00
Melting point (Kelvin)
213.20
Boiling point (Celsius)
198.50
Boiling point (Kelvin)
471.60
General information
Molecular weight
82.11g/mol
Molar mass
82.1090g/mol
Density
1.0300g/cm3
Appearence

1-Methylimidazole is a clear, colorless to pale yellow liquid. It is hygroscopic, meaning it readily absorbs moisture from the air, and it has a distinct, amine-like odor.

Comment on solubility

Solubility of 1-methylimidazole (C4H6N2)

1-methylimidazole is a fascinating compound due to its solubility characteristics. It is primarily known for being soluble in a variety of polar solvents, which significantly enhances its utility in chemical applications. Here are some key points about its solubility:

  • Polar Solvents: 1-methylimidazole readily dissolves in polar solvents such as water, methanol, and ethanol. This is largely due to its ability to form hydrogen bonds.
  • Hydrophilicity: The presence of nitrogen atoms in the imidazole ring contributes to its hydrophilic nature, facilitating interactions with water molecules.
  • Temperature Effect: Solubility can be temperature-dependent, with increased temperature often resulting in higher solubility. This is a common characteristic of many organic compounds.
  • General Applications: As a soluble compound, 1-methylimidazole is commonly used in synthesis reactions, ionic liquids, and as a catalyst in various organic transformations.

In conclusion, the solubility of 1-methylimidazole in polar solvents makes it a versatile compound in both laboratory settings and industrial applications. Its unique properties allow for a range of interactions, making it an important subject of study in the field of chemical science.

Interesting facts

Interesting Facts about 1-Methylimidazole

1-Methylimidazole is an intriguing compound with a variety of applications, which stems from its unique structure and properties. Here are some notable aspects:

  • Structural Versatility: As a derivative of imidazole, 1-methylimidazole features a methyl group attached to the nitrogen atom in the five-membered ring, enhancing its reactivity and solubility in polar solvents.
  • Biological Importance: 1-Methylimidazole is not just a laboratory compound; it is of interest in biological systems. It's a part of various biochemical pathways which can impact metabolic processes.
  • Applications in Synthesis: This compound serves as a valuable building block in organic synthesis. It is frequently used in the preparation of pharmaceuticals, agrochemicals, and other functional organic molecules.
  • Catalysis and Ionic Liquids: 1-Methylimidazole is often used in the synthesis of ionic liquids, which are utilized as green solvents and catalysts in chemical reactions. Their low volatility and high thermal stability make them ideal for various applications.

As a chemical scientist or student delving into organic chemistry, understanding compounds like 1-methylimidazole allows for a greater appreciation of the subtle nuances of nitrogen-containing heterocycles. The potential for innovation with such compounds is immense, highlighting the role of small structural changes in altering chemical behavior and function.

In the words of renowned chemist Linus Pauling, "The best way to have a good idea is to have lots of ideas." Experimenting with compounds like 1-methylimidazole opens the door to endless possibilities in both research and application.

Synonyms
1-methylimidazole
1-Methyl-1H-imidazole
616-47-7
N-Methylimidazole
1H-Imidazole, 1-methyl-
IMIDAZOLE, 1-METHYL-
N-methylimidazol
1-methylimidazol
n-methyl imidazole
N1-Methylimidazole
Araldite DY 070
EINECS 210-484-7
UNII-P4617QS63Y
MFCD00005292
NSC 88064
DTXSID6052291
CHEBI:113454
P4617QS63Y
NSC-88064
1-methyl-1H-imidazol-3-ium
DTXCID6030863
EC 210-484-7
THIAMAZOLE IMPURITY B [EP IMPURITY]
1-methyl-imidazole
1-methylimdazole
THIAMAZOLE IMPURITY B (EP IMPURITY)
1-methylimidazolium ethanoate
NMethylimidazole
1-Methyl-1H-imidazole; Thiamazole Imp. B (EP); Thiamazole Impurity B
3-methylimidazole
N-methyl-imidazol
N-methyl-imidazole
1-methyl imidazole
Imidazole, 1methyl
1-N-methylImidazole
1HImidazole, 1methyl
Lopac-M-8878
1-methyl-(1H)-imidazole
CHEMBL543
1-Methyl-1H-imidazole #
WLN: T5N CNJ A1
Lopac0_000831
3-methyl-1H-imidazol-3-ium
BDBM7884
HMS3262H03
BCP29437
NSC88064
STR00990
Tox21_304006
Tox21_500831
BBL011447
STL146559
AKOS000119840
CCG-204915
CS-W008580
FM00853
LP00831
PS-9372
SDCCGSBI-0050808.P002
NCGC00015702-01
NCGC00015702-02
NCGC00015702-03
NCGC00015702-04
NCGC00094162-01
NCGC00094162-02
NCGC00261516-01
NCGC00357222-01
1-Methylimidazole, ReagentPlus(R), 99%
1-Methylimidazole, redistilled from glass
CAS-616-47-7
FM179985
PD015169
DB-002020
EU-0100831
M0508
NS00009025
EN300-21628
1-Methylimidazole, puriss., >=99.0% (GC)
D70869
M 8878
1-Methylimidazole, Vetec(TM) reagent grade, 98%
SR-01000076013
Q4545792
SR-01000076013-1
1-Methylimidazole, >=99%, purified by redistillation
F0001-1635
Z104506032
1-Methyl-1H-imidazole;N-Methylimidazole;1H-Imidazole, 1-methyl-
210-484-7
Cap B (1-methylimidazole 16% in THF), for oligonucleotide synthesis, filtered through a 1mum filter
Capping B (10 % N-methylimidazole in THF / pyridine, V / V = 80 : 10) NC-0803 emp Biotech GmbH
Capping B, 16 % NMI in THF, emp Biotech GmbH (THF/N-methylimidazole, V / V = 84 : 16) NC-0801, 450ml : 28-400 thread, 2.5L : GL45 thread