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PB-22

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Identification
Molecular formula
C23H22N4O
CAS number
1400742-17-7
IUPAC name
1-methyl-N-(8-methyl-8-azabicyclo[3.2.1]octan-3-yl)indazole-3-carboxamide
State
State

At room temperature, PB-22 is in a solid state. It is typically stable under standard environmental conditions of temperature and pressure.

Melting point (Celsius)
273.85
Melting point (Kelvin)
547.00
Boiling point (Celsius)
519.85
Boiling point (Kelvin)
793.00
General information
Molecular weight
376.46g/mol
Molar mass
376.4870g/mol
Density
1.2180g/cm3
Appearence

PB-22 is typically found as a white to off-white crystalline powder. It has a texture similar to fine grains or a smooth powder. The appearance can vary slightly depending on the purity and specific formulation of the compound.

Comment on solubility

Solubility of 1-methyl-N-(8-methyl-8-azabicyclo[3.2.1]octan-3-yl)indazole-3-carboxamide

The solubility of 1-methyl-N-(8-methyl-8-azabicyclo[3.2.1]octan-3-yl)indazole-3-carboxamide, with the molecular formula C23H22N4O, can be characterized by several key factors:

  • Polarity: The presence of functional groups, such as carboxamide, can affect solubility in polar solvents like water.
  • Hydrogen Bonding: The ability of the molecule to engage in hydrogen bonding may enhance its solubility in polar solvents.
  • Nonpolar Character: The hydrophobic sections of the compound may lead to reduced solubility in aqueous environments.

Generally, compounds that are largely hydrophobic tend to have lower solubility in water, whereas those with polar or charged groups are typically more soluble. The intricate balance between these properties makes predicting the solubility of such complex organic molecules particularly challenging. As a rule of thumb, we can summarize:

  1. If the compound has significant polar characteristics, expect higher solubility in polar solvents.
  2. If the compound is predominantly nonpolar, anticipate lower solubility in water, but potentially higher solubility in organic solvents.

In conclusion, the solubility of 1-methyl-N-(8-methyl-8-azabicyclo[3.2.1]octan-3-yl)indazole-3-carboxamide is influenced by its molecular structure and the surrounding environment, making it essential for researchers to conduct empirical solubility studies to understand its behavior in various solvents. Understanding these factors is crucial for applications in pharmaceuticals and materials science.

Interesting facts

Interesting Facts about 1-methyl-N-(8-methyl-8-azabicyclo[3.2.1]octan-3-yl)indazole-3-carboxamide

The compound 1-methyl-N-(8-methyl-8-azabicyclo[3.2.1]octan-3-yl)indazole-3-carboxamide exhibits intriguing chemical characteristics and has garnered attention in various fields of research. Below are some fascinating insights:

  • Medicinal Potential: Due to the presence of an indazole moiety, this compound may possess interesting pharmacological properties, potentially related to neurological or anti-inflammatory effects.
  • Cycloalkane Structure: The bicyclic structure, particularly the azabicyclo element, endows this compound with unique stereoelectronic properties that can influence its reactivity and interaction with biological targets.
  • Structure-Activity Relationship (SAR): Understanding the molecular modifications in a compound like this may provide insights into developing more effective derivatives, highlighting the importance of chirality in creating specific interactions.
  • Research Applications: This compound is of interest in the fields of drug development and medicinal chemistry, where researchers focus on the synthesis of derivatives to explore enhanced efficacy and safety profiles.
  • Investigative Studies: Scientific studies may explore its efficacy in treating various conditions, including but not limited to, neurological disorders or mood disorders, thereby contributing to the broader understanding of its therapeutic potential.

As a chemistry student or scientist, delving into compounds like this opens a myriad of questions about how structural changes influence function and interaction. As stated by renowned chemist Linus Pauling: "The best way to have a good idea is to have a lot of ideas." This encapsulates the spirit of exploration that guides the study of such complex compounds.


Overall, the study of 1-methyl-N-(8-methyl-8-azabicyclo[3.2.1]octan-3-yl)indazole-3-carboxamide not only enriches our understanding of organic compounds but also illuminates pathways for innovative solutions in medicine and beyond.

Synonyms
LY 278584
119193-37-2
LY-278,584 maleate
1-Methyl-N-(8-methyl-8-azabicyclo(3.2.1)oct-3-yl)-1H-indazole-3-carboxamide
1-methyl-N-(8-methyl-8-azabicyclo[3.2.1]octan-3-yl)indazole-3-carboxamide
LY278584
1-methyl-N-(8-methyl-8-azabicyclo[3.2.1]octan-3-yl)-3-indazolecarboxamide
Biomol-NT_000163
Lopac0_000741
BPBio1_000507
CHEMBL291046
SCHEMBL9485783
BDBM84739
CHEBI:91535
DTXSID10922885
BCP33041
NSC_3970
UEA19337
AKOS040748814
CCG-204826
NCGC00015585-02
NCGC00015585-03
NCGC00162234-01
NCGC00162234-02
DA-75188
HY-124117
CAS_109216-58-2
CS-0084243
LY-278584; LY278584
BRD-A12016240-001-01-7
Q27163369
Z2714240088
1-methyl-N-(8-methyl-8-azabicyclo[3.2.1]-oct-3-yl)-1h-indazole-3-carboxamide
1-Methyl-N-(8-methyl-8-azabicyclo[3.2.1]octan-3-yl)-1H-indazole-3-carboxamide
1-Methyl-N-[(3-endo)-8-methyl-8-azabicyclo[3.2.1]-oct-3-yl]-1H-indazole-3-carboxamide
1H-Indazole-3-carboxamide, 1-methyl-N-(8-methyl-8-azabicyclo(3.2.1)oct-3-yl)-