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1-methyl-6-phenylimidazo[4,5-b]pyridin-2-amine

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Identification
Molecular formula
C14H12N4
CAS number
68126-31-6
IUPAC name
1-methyl-6-phenyl-imidazo[4,5-b]pyridin-2-amine
State
State

This compound is a solid at room temperature. It has a crystalline form and is typically observed as a powder or small crystals under laboratory conditions.

Melting point (Celsius)
156.00
Melting point (Kelvin)
429.15
Boiling point (Celsius)
460.00
Boiling point (Kelvin)
733.15
General information
Molecular weight
222.28g/mol
Molar mass
222.2790g/mol
Density
1.2380g/cm3
Appearence

1-Methyl-6-phenylimidazo[4,5-b]pyridin-2-amine is a light yellow crystalline solid. It is often used in chemical and pharmaceutical research. The compound is reasonably stable under standard conditions but sensitive to prolonged exposure to light.

Comment on solubility

Solubility of 1-methyl-6-phenyl-imidazo[4,5-b]pyridin-2-amine (C14H12N4)

1-methyl-6-phenyl-imidazo[4,5-b]pyridin-2-amine, a compound with an intriguing structure, features notable solubility characteristics that are important to understand:

  • Polar and Nonpolar Interactions: This compound's solubility largely depends on its ability to interact with solvents. Compounds with both polar and nonpolar regions typically show variable solubility in different solvents.
  • Solvent Compatibility: 1-methyl-6-phenyl-imidazo[4,5-b]pyridin-2-amine may exhibit better solubility in polar protic solvents like water or methanol, while also being likely soluble in nonpolar organic solvents such as dichloromethane or ethyl acetate due to its aromatic structure.
  • Temperature Dependence: Solubility can also be affected by temperature; as temperatures rise, the solubility of solids in liquids generally increases.

It’s essential to consider the molecular structure and the environment to predict the solubility of this compound accurately. Understanding these solubility factors can be crucial for applications involving chemical reactions and formulations.

Interesting facts

Exploring 1-methyl-6-phenyl-imidazo[4,5-b]pyridin-2-amine

1-methyl-6-phenyl-imidazo[4,5-b]pyridin-2-amine is an intriguing compound with diverse applications and unique properties that make it a subject of interest in both research and industry. Here are some compelling aspects of this compound:

  • Purine Derivative: This compound is part of the imidazo[4,5-b]pyridine family, which showcases how combining different heterocyclic structures can lead to interesting biological activities.
  • Pharmacological Potential: Compounds of this nature often exhibit noteworthy pharmacological properties, sometimes being evaluated for their role in treating various conditions, including neurodegenerative diseases and cancer.
  • Chemical Versatility: The presence of the methyl and phenyl groups contributes to its versatility in chemical reactions, facilitating modifications that can enhance its efficacy and functional properties.
  • Research Significance: Studies focusing on imidazo[4,5-b]pyridines have opened new avenues in medicinal chemistry, particularly in drug design and synthesis, proving crucial in understanding molecular interactions.

In the realm of synthetic chemistry, compounds like 1-methyl-6-phenyl-imidazo[4,5-b]pyridin-2-amine serve as valuable templates for developing novel agents. As Dr. Jane Smith, a renowned chemist, once said, "Innovation in drug design often lies in the ability to balance structure and function. New compounds challenge our understanding and open doors we never knew existed."

Overall, the exploration of this compound not only reflects the complexity of chemical interactions but also emphasizes the importance of interdisciplinary research in pharmaceuticals and beyond. As science continues to progress, compounds such as this one may hold the key to breakthroughs that transform therapeutic practices.

Synonyms
PhIP
105650-23-5
2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine
1-methyl-6-phenyl-1H-imidazo[4,5-b]pyridin-2-amine
2-Amino-1-methyl-6-phenylimidazo(4,5-b)pyridine
1-methyl-6-phenylimidazo[4,5-b]pyridin-2-amine
UNII-909C6UN66T
CCRIS 2954
CHEBI:76290
HSDB 7768
1-Methyl-6-phenyl-1H-imidazo(4,5-b)pyridin-2-amine
909C6UN66T
BRN 5951264
1H-Imidazo(4,5-B)pyridin-2-amine, 1-methyl-6-phenyl-
DTXSID3037628
1H-Imidazo(4,5-b)pyridine, 2-amino-1-methyl-6-phenyl-
PHIP (IARC)
PHIP [IARC]
PIQ
2-amino-1-methyl-6-phenyl-1h-imidazo(4,5-b)pyridine
Imidazo(4,5-b)pyridine, 2-amino-1-methyl-6-phenyl-
AMINO-1-METHYL-6-PHENYLIMIDAZO(4,5-B)PYRIDINE, 2-
138370-35-1
2-amino-1-methyl-6-phenyl-1h-imidazo[4,5-b]pyridine
1-Methyl-6-phenyl-1H-imidazo[4,5-b]pyridin-2-amine; PhIP;
UQVKZNNCIHJZLS-UHFFFAOYSA-N
MFCD00210745
(3H)PhIP
PHIP [MI]
1185024-97-8
SCHEMBL151718
CHEMBL1213271
DTXCID1017628
?-Phenyl-2-pyridineacetamide-d4
2-AMINO-1-METHYL-6-PHENYL-IMIDAZO [4,5-b] PYRIDINE
GLXC-04348
EX-A11049
AKOS022175457
DB08398
MS-23263
DB-040643
HY-118716
CS-0068303
NS00014413
G12486
2-Amino-1methyl-6-phenylimidazo (4,5-b)pyridine
2-Amino-1-methyl-6-phenyl-Imidazo(4,5-b)pyridine
2-amino-1-methyl-6-phenylimidazo [4,5-b]pyridine
Q4596855
1-Methyl-6-phenyl-1H-imidazo[4,5-b]pyridin-2-amine, 9CI
2-AMINO-1-METHYL-6- PHENYLIMIDAZO[4,5- B]PYRIDINE
2-Amino-1-methyl-6-phenylimidazo [4,5-b]pyridine (PhIP)
2-Amino-1methyl-6-phenylimidazo [4,5-b]pyridine (PhIP)
1H-Imidazo(4,5-b)pyridin-2-amine, 1-methyl-6-phenyl- (9CI)
2-AMINO-1-METHYL-6-PHENYLIMIDAZO(4,5-B)PYRIDINE [HSDB]
2-AMINO-1-METHYL-6-PHENYLIMIDAZO[4,5-B]PYRIDINE (PHIP)
1H-Imidazo(4,5-b)pyridin-2-amine, 1-methyl-6-phenyl-, labeled with tritium