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Tirazone

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Identification
Molecular formula
C6H7N3O2
CAS number
15167-48-5
IUPAC name
1-methyl-6-oxo-4,5-dihydropyridazine-3-carboxamide
State
State

At room temperature, Tirazone is in a solid state. The compound is stable and does not vaporize easily, making it relatively inert under standard conditions.

Melting point (Celsius)
178.99
Melting point (Kelvin)
452.14
Boiling point (Celsius)
313.15
Boiling point (Kelvin)
586.30
General information
Molecular weight
167.15g/mol
Molar mass
167.1480g/mol
Density
1.3642g/cm3
Appearence

Tirazone appears as a crystalline solid that is typically white or off-white in color. The compound's crystalline structure contributes to its solid-state form at room temperature.

Comment on solubility

Solubility of 1-methyl-6-oxo-4,5-dihydropyridazine-3-carboxamide

The solubility of 1-methyl-6-oxo-4,5-dihydropyridazine-3-carboxamide can be characterized by several key factors:

  • Polarity: The presence of functional groups such as the carboxamide (-CO-NH2) influences the compound's polarity, typically enhancing solubility in polar solvents.
  • Hydrogen Bonding: This compound can engage in hydrogen bonding due to the amide group, which can further increase solubility in water.
  • Solvent Effects: It is likely to be more soluble in polar organic solvents such as methanol and ethanol compared to non-polar solvents like hexane.
  • Temperature Influence: Generally, increasing temperature may improve solubility, making the compound more soluble in hot solvents.

In summary, while precise solubility data for 1-methyl-6-oxo-4,5-dihydropyridazine-3-carboxamide may vary under different conditions, its functional groups suggest it possesses a reasonable solubility profile in polar settings. Therefore, when working with this compound, it is essential to consider the solvent environment to optimize its solubility characteristics.

Interesting facts

Interesting Facts about 1-methyl-6-oxo-4,5-dihydropyridazine-3-carboxamide

1-methyl-6-oxo-4,5-dihydropyridazine-3-carboxamide is a fascinating compound that showcases a unique structure and versatile chemistry. Here are some intriguing aspects of this compound:

  • Structural Features: This compound belongs to the pyridazine family, characterized by a six-membered ring containing two nitrogen atoms. The presence of a carboxamide functional group enhances its reactivity and solubility in various solvents.
  • Biological Significance: Variants of pyridazine derivatives have been studied for their biological activities, including antimicrobial and antifungal properties. This makes compounds like 1-methyl-6-oxo-4,5-dihydropyridazine-3-carboxamide of interest in pharmaceutical research.
  • Synthesis Routes: The compound can be synthesized through various organic reactions, highlighting the importance of reaction conditions and catalysts in controlling the yield and purity of the final product.
  • Applications: Beyond potential pharmaceutical uses, 1-methyl-6-oxo-4,5-dihydropyridazine-3-carboxamide can also serve as a versatile intermediate in the synthesis of other complex organic compounds, expanding its utility in synthetic organic chemistry.
  • Research Insights: Ongoing studies aim to explore its interaction with biological targets, which can lead to the development of new therapeutic agents.

In summary, 1-methyl-6-oxo-4,5-dihydropyridazine-3-carboxamide is a compound rich in potential, both in terms of its structural properties and its application in the realm of medicinal chemistry. As researchers continue to unlock its secrets, this compound promises to contribute to the advancement of chemical science.

Synonyms
MEDAZOMIDE
300-22-1
medazonamide
Medazomide [INN]
Medazomida
Medazomidum
Medazomidum [INN-Latin]
1-methyl-6-oxo-1,4,5,6-tetrahydropyridazine-3-carboxamide
Medazomida [INN-Spanish]
L-1777
UNII-4Q1Q4V31K8
DTXSID5057705
4Q1Q4V31K8
1,4,5,6-Tetrahydro-1-methyl-6-oxo-3-pyridazinecarboxamide
DTXCID3031494
1-methyl-6-oxo-4,5-dihydropyridazine-3-carboxamide
Catos; L 1777; Medazomid; Medazonamide
Medazomidum (INN-Latin)
Medazomida (INN-Spanish)
L 1777
SCHEMBL1817436
CHEMBL2104736
3-Pyridazinecarboxamide, 1,4,5,6-tetrahydro-1-methyl-6-oxo-
AAA30022
Tox21_113915
AKOS009086899
NCGC00262918-01
CAS-300-22-1
DB-421175
NS00123342
EN300-94794
SR-01000945203
SR-01000945203-1
BRD-K00019835-001-01-4
Q27260349
Z168362628