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Nicotine N-oxide

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Identification
Molecular formula
C10H14N2O
CAS number
1008-72-6
IUPAC name
1-methyl-2-(3-pyridyl)pyrrolidin-2-ol
State
State
This compound typically exists as a liquid at room temperature, though it can crystallize under certain conditions.
Melting point (Celsius)
39.00
Melting point (Kelvin)
312.15
Boiling point (Celsius)
275.00
Boiling point (Kelvin)
548.15
General information
Molecular weight
162.23g/mol
Molar mass
162.2110g/mol
Density
1.1600g/cm3
Appearence

Nicotine N-oxide is typically found as a liquid or crystalline solid. It is colorless to pale yellow, and can appear oily.

Comment on solubility

Solubility of 1-methyl-2-(3-pyridyl)pyrrolidin-2-ol (C10H14N2O)

The solubility of 1-methyl-2-(3-pyridyl)pyrrolidin-2-ol is a significant aspect to consider when examining its behavioral characteristics in various environments. This compound, characterized by its unique structure, demonstrates variable solubility depending on the solvent used. Here are a few key points regarding its solubility:

  • Solvent Dependence: This compound is likely to exhibit higher solubility in polar solvents due to the presence of the hydroxyl group (-OH) as well as the nitrogen atoms, which can form hydrogen bonds.
  • Water Solubility: While specific solubility values may vary, compounds containing nitrogen and hydroxyl groups typically show some degree of water solubility, suggesting that 1-methyl-2-(3-pyridyl)pyrrolidin-2-ol may also dissolve to a certain extent in aqueous solutions.
  • Organic Solvents: Increased solubility can be expected in organic polar solvents such as ethanol or methanol, which can accommodate the compound's unique structure and functional groups.
  • Implications: Understanding solubility is crucial for applications in pharmaceuticals and chemical synthesis, as it impacts the bioavailability, effective dosage, and formulation of the compound in various contexts.

In summary, the solubility behavior of 1-methyl-2-(3-pyridyl)pyrrolidin-2-ol can influence its application and utility, making it a pivotal factor for scientists working with this compound.

Interesting facts

Interesting Facts about 1-methyl-2-(3-pyridyl)pyrrolidin-2-ol

1-methyl-2-(3-pyridyl)pyrrolidin-2-ol is a fascinating compound that has attracted attention in various fields of chemistry, particularly in medicinal chemistry and organic synthesis. Here are some key points that highlight its significance:

  • Molecular Diversity: This compound features a unique structure that combines a pyrrolidine ring with a pyridine moiety, allowing it to exhibit various chemical properties and biological activities.
  • Medicinal Potential: The inclusion of a pyridine ring is often associated with biological activity, and compounds like this have been studied for their potential roles as pharmacophores, which can interact with biological targets to elicit therapeutic effects.
  • Synthetic Routes: Its synthesis often involves multiple steps, showcasing the ingenuity of synthetic organic chemistry. Researchers employ methods such as C–H functionalization and ring-closing reactions to construct this compound efficiently.
  • Derivative Exploration: The structural components of 1-methyl-2-(3-pyridyl)pyrrolidin-2-ol enable chemists to develop derivatives that may enhance its efficacy or selectivity in biological applications.
  • Research Applications: Studies have suggested that compounds with this kind of structure may play a role in the development of treatments for neurodegenerative disorders and other conditions, making them a target of current pharmaceutical research.

Quoting renowned chemist Linus Pauling, "The best way to have a good idea is to have a lot of ideas." This encapsulates the spirit of innovation that surrounds compounds such as 1-methyl-2-(3-pyridyl)pyrrolidin-2-ol, as ongoing research continues to unearth their potential while inspiring new ideas in medicinal chemistry.

Synonyms
1824020-12-3
2a(2)-Hydroxynicotine
1-methyl-2-(pyridin-3-yl)pyrrolidin-2-ol
SCHEMBL16206523
DTXSID901271271
2-Pyrrolidinol, 1-methyl-2-(3-pyridinyl)-