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Tetraethylene glycol dimethyl ether

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Identification
Molecular formula
C10H22O5
CAS number
143-24-8
IUPAC name
1-methoxy-2-[2-(2-methoxyethoxy)ethoxy]ethane
State
State

Tetraethylene glycol dimethyl ether is in a liquid state at room temperature. It is miscible with water and various organic solvents.

Melting point (Celsius)
-68.00
Melting point (Kelvin)
205.20
Boiling point (Celsius)
275.30
Boiling point (Kelvin)
548.40
General information
Molecular weight
194.28g/mol
Molar mass
194.2500g/mol
Density
1.0155g/cm3
Appearence

Tetraethylene glycol dimethyl ether is a colorless, viscous liquid. It has a slightly sweet odor that is characteristic of ethers.

Comment on solubility

Solubility of 1-methoxy-2-[2-(2-methoxyethoxy)ethoxy]ethane

The solubility of 1-methoxy-2-[2-(2-methoxyethoxy)ethoxy]ethane, a complex ether compound, is influenced by its molecular structure consisting of several ether linkages and ethoxy groups. Here are some key points regarding its solubility:

  • Polar Character: The presence of multiple methoxy and ethoxy groups increases the overall polarity of the compound, enhancing its solubility in polar solvents such as water, although to a limited extent.
  • Hydrogen Bonding: The ability of the compound to form hydrogen bonds with water molecules can facilitate its dissolution.
  • Hydrophobic Regions: However, the hydrophobic carbon chain can hinder complete solubility in water, making it more soluble in organic solvents like ethanol or acetone.
  • Solvent Suitability: For practical applications, it is most effectively dissolved in solvents that can accommodate its ether functionalities.

Overall, while 1-methoxy-2-[2-(2-methoxyethoxy)ethoxy]ethane exhibits moderate solubility characteristics, the specifics can vary significantly depending on the solvent choice. As stated, "Like dissolves like," meaning that its solubility will be most favorable in similar polar or non-polar solvents as its structure suggests.

Interesting facts

Interesting Facts about 1-Methoxy-2-[2-(2-methoxyethoxy)ethoxy]ethane

1-Methoxy-2-[2-(2-methoxyethoxy)ethoxy]ethane, often recognized for its intricate structure, is a fascinating compound within the realm of organic chemistry. This compound belongs to a class of molecules known as polyether compounds, which are widely appreciated for their versatile applications in various fields.

Key Characteristics

  • Versatile Applications: This compound serves as a valuable solvent and reagent in many chemical processes, particularly in organic synthesis.
  • Polyether Chemistry: The repeated ether linkages in its structure provide unique properties that enhance solubility and stability in a variety of environments.
  • Biocompatibility: Its structure suggests potential applications in the biomedical field, particularly concerning drug delivery systems and other uses where biocompatibility is crucial.

Chemical Structure Insight

The complex arrangement of methoxy and ethoxy groups contributes to the compound's distinct characteristics. Here are some intriguing details about its structure:

  • Functional Groups: The presence of methoxy groups aids in increasing solubility and can impact the reactivity of the compound.
  • Ether Linkages: The ether linkages in polyethers typically lead to low toxicity and good thermal stability, which are advantageous in many practical applications.

Quote from Chemistry

As noted in chemistry research, “The intricate balance of structure and function in polyether compounds like 1-methoxy-2-[2-(2-methoxyethoxy)ethoxy]ethane reflects the innovation of molecular design in man-made materials.” This highlights the ongoing exploration in materials science and organic chemistry.

In conclusion, 1-methoxy-2-[2-(2-methoxyethoxy)ethoxy]ethane is more than just a compound; it is a testament to the ingenuity found in the chemical world, paving the way for innovative applications and deeper understanding in the realm of chemistry.

Synonyms
Triglyme
112-49-2
2,5,8,11-TETRAOXADODECANE
Triethylene glycol dimethyl ether
1,2-Bis(2-methoxyethoxy)ethane
Glyme 4
Ansul ether 161
Glyme-3
1-methoxy-2-[2-(2-methoxyethoxy)ethoxy]ethane
TEGDIME
TEGDME
Dimethyl ether of triethylene glycol
NSC 66400
Ethane, 1,2-bis(2-methoxyethoxy)-
DTXSID8026224
EINECS 203-977-3
Glycol, triethylene-, dimethyl ether
BRN 1700630
32YXG88KK0
1-METHOXY-2-[2-(2-METHOXY-ETHOXY]-ETHANE
CHEBI:44842
AI3-28582
TRIGLYME [MI]
NSC-66400
1,2-Bis(methoxyethoxy)ethane
Triethylene glycol dimethyl ether (stabilized with BHT)
DTXCID206224
triethyleneglycol dimethyl ether
EC 203-977-3
PG5
1-methoxy-2-(2-(2-methoxyethoxy)ethoxy)ethane
UNII-32YXG88KK0
Dimethyltriglycol
Glyme-4
MFCD00008504
METHYLTRIGLYME
HISOLVE MTM
1,2-Bis(2-methoxyethoxy) Ethane, Reagent
2,8,11-Tetraoxadodecane
1,2Bis(methoxyethoxy)ethane
2,5,8,11Tetraoxadodecane
SCHEMBL16126
1,2Bis(2methoxyethoxy)ethane
triethylene glycol dimethylether
CHEMBL1235255
Ethane, 1,2bis(2methoxyethoxy)
Ethane,2-bis(2-methoxyethoxy)-
(CH3O(CH2)2OCH2)2
Glycol, triethylene, dimethyl ether
NSC66400
UYB19216
Tox21_300509
AKOS009158244
CS-W017328
DB02078
NCGC00164017-01
NCGC00164017-02
NCGC00254323-01
CAS-112-49-2
DB-060211
B0496
NS00010633
EN300-40253
E75964
Q2453066
Triethylene glycol dimethyl ether, ReagentPlus(R), 99%
Z409380232
Triethylene glycol dimethyl ether 100 microg/mL in Acetonitrile
Triethylene glycol dimethyl ether, analytical reference material
2,5,8,11-tetraoxadodecane;1,2-bis(2-methoxyethoxy)ethane;triethylene glycol dimethyl ether;1,2bis(2methoxyethoxy)ethane;triethylene glycoldimethylether (tegdme);2,5,8,11-tetraoxadodecane 1,2-bis(2-methoxyethoxy)ethane triethylene glycol dimethyl ether 1,2bis(2methoxyethoxy)ethane triethylene glycoldimethylether (tegdme)
203-977-3