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Propranolol

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Identification
Molecular formula
C16H21NO2
CAS number
525-66-6
IUPAC name
1-(isopropylamino)-3-(1-naphthyloxy)propan-2-ol
State
State

At room temperature, propranolol is typically in a solid state, appearing as white crystalline powder.

Melting point (Celsius)
96.00
Melting point (Kelvin)
369.20
Boiling point (Celsius)
306.50
Boiling point (Kelvin)
579.70
General information
Molecular weight
259.35g/mol
Molar mass
259.3490g/mol
Density
1.1160g/cm3
Appearence

Propranolol is a crystalline solid that appears as white to off-white granules or powder. It is odorless and has a slightly bitter taste.

Comment on solubility

Solubility of 1-(isopropylamino)-3-(1-naphthyloxy)propan-2-ol (C16H21NO2)

The solubility of 1-(isopropylamino)-3-(1-naphthyloxy)propan-2-ol, a complex organic compound, is influenced by its unique structural features. This compound exhibits distinct solubility characteristics due to its hydrophilic and hydrophobic regions. Understanding these solubility properties is crucial for predicting its behavior in various environments.

Factors Affecting Solubility:

  • Polarity: The presence of the isopropylamino group enhances polarity, potentially increasing solubility in polar solvents such as water.
  • Hydrophobic Interactions: The naphthyloxy moiety contributes to hydrophobic interactions, which can limit solubility in polar environments.
  • pH Levels: Variations in pH can affect the ionization of the amino group, thereby influencing solubility in aqueous solutions.
  • Temperature: Higher temperatures can increase solubility for many organic compounds, though this can vary based on the specific compound structure.

To sum up, while 1-(isopropylamino)-3-(1-naphthyloxy)propan-2-ol may demonstrate moderate solubility in polar solvents, its degree of solubility will greatly depend on the solvent conditions, including pH and temperature. As is often the case with organic compounds, the interplay between hydrophilicity and hydrophobicity shapes solubility outcomes. Thus, experimentation in relevant conditions is recommended to ascertain exact solubility levels.

Interesting facts

Interesting Facts about 1-(isopropylamino)-3-(1-naphthyloxy)propan-2-ol

1-(isopropylamino)-3-(1-naphthyloxy)propan-2-ol, often referred to in the scientific community as a synthetic compound, is noteworthy for a variety of reasons:

  • Pharmaceutical Applications: This compound has potential usage in the pharmaceutical industry. Its structure may play a key role in developing medications that target specific biological pathways.
  • Unique Structure: The presence of both isopropylamino and naphthyloxy groups in its molecular framework imparts unique chemical properties, enabling interactions in various biological systems.
  • Reactivity: The secondary alcohol functional group in the molecule can participate in numerous chemical reactions, such as oxidation or esterification, making it versatile for synthetic organic chemistry.
  • Research Interest: Ongoing research in medicinal chemistry is focusing on compounds like this one to explore their efficacy as potential therapeutic agents due to their ability to modulate neurotransmitter pathways.
  • Potential Derivatives: The structure of 1-(isopropylamino)-3-(1-naphthyloxy)propan-2-ol invites chemists to create derivatives that might enhance specific activity or reduce side effects when used in biological systems.

This compound serves as a prime example of how intricate molecular architectures can lead to exciting opportunities in drug discovery and development. The fusion of seemingly simple functional groups can generate effective pharmacological agents with targeted mechanisms of action.

As scientists continue to explore the functionalities of molecules like 1-(isopropylamino)-3-(1-naphthyloxy)propan-2-ol, it highlights the importance of interdisciplinary collaboration in chemistry, pharmacology, and therapeutic innovation.

Synonyms
propranolol
525-66-6
Propanolol
beta-Propranolol
Betalong
Euprovasin
Proprasylyt
Reducor
Propanalol
Anapriline
Propanix
propranololo
Corpendol
Sawatal
dl-propranolol
Sumial
Inderal
Racemic propranolol
Propranololum
D,L-Propranolol
(+-)-Propranolol
1-naphthalen-1-yloxy-3-(propan-2-ylamino)propan-2-ol
racemic-Propranolol
.beta.-Propranolol
1-Isopropylamino-3-(naphthalen-1-yloxy)-propan-2-ol
CCRIS 3082
1-((1-Methylethyl)amino)-3-(1-naphthalenyloxy)-2-propanol
1-(isopropylamino)-3-(1-naphthyloxy)propan-2-ol
Propanolol [INN-Spanish]
UNII-9Y8NXQ24VQ
Propranololum [INN-Latin]
EINECS 208-378-0
EINECS 235-867-6
9Y8NXQ24VQ
hemangiol
1-Isopropylamino-3-(1-naphthyloxy)-2-propanol
Bedranol
CHEBI:8499
2-Propanol, 1-((1-methylethyl)amino)-3-(1-naphthalenyloxy)-
(+/-)-propranolol
2-Propanol, 1-(isopropylamino)-3-(1-naphthyloxy)-
CHEMBL27
rac-Propanolol
AY-64043-
Betadren
DTXSID6023525
2-Propanol, 1-(isopropylamino)-3-(1-naphthyloxy)-, (+-)-
2-Propanol, 1-[(1-methylethyl)amino]-3-(1-naphthalenyloxy)-
Inderex
Inderol
Pranolol
Propranolol (INN)
(1)-1-(Isopropylamino)-3-(naphthyloxy)propan-2-ol
13013-17-7
1-(naphthalen-1-yloxy)-3-(propan-2-ylamino)propan-2-ol
PROPRANOLOL [INN]
2-Propanol, 1-((1-methylethyl)amino)-3-(1-naphthalenyloxy)-, (+-)-
Inderal hydrochloride
Propanolol (INN-Spanish)
Propranololum (INN-Latin)
Propranololo [DCIT]
3-(naphthalen-1-yloxy)-1-(propan-2-ylamino)propan-2-ol
Propranalol
1-(naphthalen-1-yloxy)-3-[(propan-2-yl)amino]propan-2-ol
Propranolol [INN:BAN]
AY 20694
b-Propranolol
Propranolol (TN)
Dociton (Salt/Mix)
Inderal (Salt/Mix)
Obsidan (Salt/Mix)
Propanolol,(+/-)
PROPRANOLOL, d
Avlocardyl (Salt/Mix)
beta-Propranolol;Dociton
PROPANOLOL(-)
PROPRANOLOL [MI]
Prestwick0_000952
Prestwick1_000952
Prestwick2_000952
Prestwick3_000952
PROPRANOLOL,(+)
PROPRANOLOL,(-)
Spectrum2_001301
Spectrum2_001699
Spectrum3_000883
Spectrum3_001071
Spectrum4_000974
Spectrum4_001222
Spectrum5_000751
(.+/-.)-Propranolol
PROPRANOLOL [VANDF]
SCHEMBL3955
(S)-1-(isopropylamino)-3-(naphthalen-1-yloxy)propan-2-ol
3-[(methylethyl)amino]-1-naphthyloxypropan-2-ol
Lopac0_000896
Oprea1_304193
BSPBio_000944
BSPBio_002682
CBDivE_006180
GTPL564
KBioGR_001347
KBioGR_001684
KBioGR_002515
KBioSS_002523
PROPRANOLOL [WHO-DD]
DivK1c_000023
SPBio_001361
SPBio_001658
SPBio_003093
(+)-Propranolol hydrochloride; (R)-(+)-Propranolol hydrochloride
1-(Isopropylamino)-3-(naphthalen-1-yloxy)propan-2-ol
BPBio1_001040
DTXCID903525
ICI 45520 (Salt/Mix)
NSC 91523 (Salt/Mix)
SCHEMBL12264958
BDBM25761
HY-B0573B
KBio1_000023
KBio2_002515
KBio2_005083
KBio2_007651
KBio3_001766
KBio3_001902
KBio3_002993
C07AA05
cMAP_000071
NINDS_000023
(A+/-)-Propranolol hydrochloride
[2-hydroxy-3-(naphthalen-1-yloxy)propyl](propan-2-yl)amine
Bio1_000367
Bio1_000856
Bio1_001345
HMS2090L21
HMS3428G03
ALBB-023324
BCP26001
BCP31343
YDA89723
BBL023437
PDSP1_000767
PDSP1_001607
PDSP1_001608
PDSP2_000755
PDSP2_001591
PDSP2_001592
STK735510
AKOS000588816
AKOS016050338
CCG-103643
DB00571
FE-0204
FP27655
SDCCGSBI-0050871.P004
IDI1_000023
NCGC00015798-04
NCGC00015798-05
NCGC00015798-06
NCGC00015798-07
NCGC00015798-08
NCGC00015798-09
NCGC00015798-15
NCGC00015798-19
NCGC00024690-02
NCGC00024690-03
DA-57114
SBI-0050871.P003
AB00053537
CS-0069968
NS00000196
EN300-40731
C07407
D08443
G60902
AB00053537-10
AB00053537_11
AB00053537_12
1-(Isopropylamino)-3-(1-naphthoxy)-propan-2-ol
L000679
Q423364
1(-alpha-naphthoxy)-3-(iso-propylamino)-2-propanol
1-(alpha-naphthoxy)-3-(iso-propylamino)-2-propanol
1-(alpha-naphthoxy)-3-(isopropylamino)-2-propanol
1-(isopropylamino)-3-naphthalen-1-yloxy-propan-2-ol
BRD-A10070317-003-06-9
BRD-A10070317-003-17-6
BRD-A10070317-003-28-3
BRD-A10070317-003-29-1
BRD-A10070317-003-30-9
1-((1-Methylethyl)amino)-3-(1-naphthyloxy)-2-propanol
1-(1-Naphthyloxy)-2-hydroxy-3-(isopropylamino)propane
F0001-3681
1-[(1-methylethyl)amino]-3-(naphthalen-1-yloxy)propan-2-ol
1[(1-Methylethyl)amino]-3-(1-naphthalenyloxy)-2-propanol hydrochloride;Angilol;Apsolol;(+/-)-Propranolol hydrochloride
208-378-0