Interesting facts
Interesting Facts about 1-ethyl-6-fluoro-4-oxo-7-piperazin-1-yl-1,8-naphthyridine-3-carboxylic acid
The compound 1-ethyl-6-fluoro-4-oxo-7-piperazin-1-yl-1,8-naphthyridine-3-carboxylic acid represents a fascinating area of organic chemistry, primarily due to its diverse biological activities and applications in medicinal chemistry.
Key Characteristics
- Pharmacological Potential: This compound belongs to a class of compounds known for their potential antimicrobial and anti-inflammatory properties, making them of great interest in drug development.
- Structural Complexity: The presence of a piperazine ring adds complexity to its structure, which is often associated with improved pharmacological activities and bioavailability.
- Fluorine Atom: The incorporation of a fluorine atom can significantly enhance the metabolic stability of the molecule, thus providing valuable insights for drug efficacy and safety.
Applications in Research
Research involving 1-ethyl-6-fluoro-4-oxo-7-piperazin-1-yl-1,8-naphthyridine-3-carboxylic acid includes:
- Mechanistic Studies: Understanding its mode of action in various biological pathways.
- Drug Design: Exploring how modifications to its structure can lead to improved therapeutic profiles.
- Toxicological Assessments: Evaluating the safety and potential side effects of the compound through various in vitro and in vivo models.
Quote from the Pharmaceutical Field
As noted in a recent study, "the unique arrangement of functional groups in compounds like 1-ethyl-6-fluoro-4-oxo-7-piperazin-1-yl-1,8-naphthyridine-3-carboxylic acid presents an exciting opportunity for the design of novel therapeutics." This highlights the ongoing interest in its synthesis and application in pharmaceutical chemistry.
In summary, 1-ethyl-6-fluoro-4-oxo-7-piperazin-1-yl-1,8-naphthyridine-3-carboxylic acid is a prime example of how intricate organic structures can lead to significant impacts in medicine and drug development.
Synonyms
enoxacin
74011-58-8
Penetrex
Enoxacine
1-Ethyl-6-fluoro-1,4-dihydro-4-oxo-7-(1-piperazinyl)-1,8-naphthyridine-3-carboxylic acid
Comprecin
Enoxacino
Bactidan
Enoxacinum
Flumark
AT-2266
Enoram
Enoxor
CI-919
Almitil
PD 107779
Enoxacinum [Latin]
enofloxacin
CI 919
PD-107779
1-ethyl-6-fluoro-4-oxo-7-(piperazin-1-yl)-1,4-dihydro-1,8-naphthyridine-3-carboxylic acid
1-ethyl-6-fluoro-4-oxo-7-piperazin-1-yl-1,8-naphthyridine-3-carboxylic acid
CCRIS 5242
NSC 629661
CHEBI:157175
Enoxacin (hydrate)
NSC 627409
NSC-629661
NSC-758416
UNII-325OGW249P
BRN 3628995
DTXSID5022984
325OGW249P
MFCD00133308
CHEMBL826
1,8-Naphthyridine-3-carboxylic acid, 1-ethyl-6-fluoro-1,4-dihydro-4-oxo-7-(1-piperazinyl)-
1-Ethyl-6-fluoro-4-oxo-7-piperazin-1-yl-1,4-dihydro-[1,8]naphthyridine-3-carboxylic acid
DTXCID002984
Enoxin
Enoxacinum (Latin)
NSC629661
1,8-Naphthyridine-3-carboxylic acid, 1,4-dihydro-1-ethyl-6-fluoro-4-oxo-7-(1-piperazinyl)-
1-ethyl-6-fluoro-4-oxo-7-piperazin-1-yl-1,4-dihydro-1,8-naphthyridine-3-carboxylic acid
AT 2266;CI 919
Enoxacine [French]
NCGC00016927-01
Enoxacin (Penetrex)
Enoxacino [Spanish]
Enoksetin
CAS-74011-58-8
ENOXACIN (MART.)
ENOXACIN [MART.]
Enoxacin sesquihydrate;AT-2266 hydrate;CI-919 hydrate
Enofloxacine
Bactidron
Enoxen
Penetrex (TN)
1,8-NAPHTHYRIDINE-3-CARBOXYLIC ACID, 1-ETHYL-6-FLUORO-1,4-DIHYDRO-4-OXO-7-(1-PIPERAZINYL)
SMR000058233
Enoxacin (USAN/INN)
SR-01000000202
Enoxacina
Abenox
1-Ethyl-6-fluoro-4-oxo-7-piperazin-1-yl-1,4-dihydro-(1,8)naphthyridine-3-carboxylic acid
Enoxacin [USAN:INN:BAN:JAN]
ENX
Prestwick_708
Spectrum_001539
ENOXACIN [USAN]
ENOXACIN [INN]
ENOXACIN [MI]
ENOXACIN [VANDF]
Prestwick0_000353
Prestwick1_000353
Prestwick2_000353
Prestwick3_000353
Spectrum2_001731
Spectrum3_001570
Spectrum4_000166
Spectrum5_001044
E0762
ENOXACIN [WHO-DD]
Epitope ID:119069
Oprea1_147866
SCHEMBL33963
BSPBio_000445
BSPBio_003080
Enoxacin, analytical standard
KBioGR_000651
KBioSS_002019
MLS000069645
MLS006011976
BIDD:GT0191
DivK1c_000420
SPECTRUM1503215
SPBio_001802
SPBio_002366
ENOXACIN [ORANGE BOOK]
BPBio1_000491
GTPL8882
BCBcMAP01_000009
HMS501E22
KBio1_000420
KBio2_002019
KBio2_004587
KBio2_007155
KBio3_002580
J01MA04
NINDS_000420
HMS1569G07
HMS1922I17
HMS2090E10
HMS2092N20
HMS2233K20
HMS3372A12
HMS3655M08
HMS3715H13
Pharmakon1600-01503215
BCP22623
HY-B0268
Tox21_110688
BDBM50296358
CCG-39452
NSC758416
s1756
AKOS015838626
Tox21_110688_1
DB00467
KS-5190
1-ethyl-6-fluoro-4-oxo-7-piperazinylhydropyridino[2,3-b]pyridine-3-carboxylic acid
IDI1_000420
SMP1_000113
NCGC00016927-02
NCGC00016927-03
NCGC00016927-04
NCGC00016927-05
NCGC00016927-06
NCGC00016927-07
NCGC00016927-08
NCGC00016927-10
NCGC00016927-11
NCGC00023864-03
NCGC00023864-04
NCGC00178309-01
NCGC00178309-02
NCI60_009618
SBI-0051788.P002
DB-055829
NS00000506
SW196857-3
C06979
D00310
EN300-122627
1, 6-fluoro-1,4-dihydro- 4-oxo-7-piperazinyl
AB00052328-09
AB00052328_10
AB00052328_11
Q1639616
SR-01000000202-2
SR-01000000202-3
BRD-K78113049-001-05-5
BRD-K78113049-001-07-1
BRD-K78113049-001-12-1
BRD-K78113049-001-15-4
BRD-K78113049-001-16-2
BRD-K78113049-001-17-0
Z1544404495
84294-96-2 (.1.5H2O)
1-Ethyl-6-fluoro-4-oxo-7-(1-piperazinyl)-1,4-dihydro[1,8]naphthyridine-3-carboxylic acid
Solubility of 1-ethyl-6-fluoro-4-oxo-7-piperazin-1-yl-1,8-naphthyridine-3-carboxylic acid (C17H18FN3O3)
The solubility of a compound can be influenced by various factors, including its structure, polarity, and the presence of functional groups. In the case of 1-ethyl-6-fluoro-4-oxo-7-piperazin-1-yl-1,8-naphthyridine-3-carboxylic acid, we observe the following:
In essence, one could anticipate that this compound may demonstrate moderate solubility in polar solvents while having limited solubility in non-polar solvents. Understanding these solubility characteristics is crucial for its application in pharmaceutical sciences and other fields.