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Azatadine

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Identification
Molecular formula
C22H25NO2
CAS number
3964-81-6
IUPAC name
(1-ethyl-3-piperidyl) 2,2-diphenylacetate
State
State

At room temperature, Azatadine is in a solid state, typically as a crystalline powder.

Melting point (Celsius)
142.00
Melting point (Kelvin)
415.15
Boiling point (Celsius)
333.70
Boiling point (Kelvin)
606.85
General information
Molecular weight
331.45g/mol
Molar mass
329.4520g/mol
Density
1.1000g/cm3
Appearence

Azatadine is a white crystalline powder. It is typically available in a pure form which appears as a white solid.

Comment on solubility

Insights on Solubility of (1-ethyl-3-piperidyl) 2,2-diphenylacetate

(1-ethyl-3-piperidyl) 2,2-diphenylacetate, with the chemical formula C22H25NO2, showcases interesting solubility characteristics that are noteworthy in various applications.

Solubility Characteristics:

  • Polarity: The presence of a piperidine ring and an ester functional group can influence its solubility, making it likely to be moderately soluble in polar solvents.
  • Solvent Compatibility: It is generally expected to dissolve well in organic solvents such as ethanol, methanol, or acetone, owing to its hydrophobic diphenylacetate moiety.
  • Limitations: In contrast, its solubility in water may be low due to the large hydrophobic regions, making it challenging to use in aqueous environments.

Understanding the solubility of this compound is crucial for its applications in pharmaceutical formulations and organic synthesis. As a rule of thumb, compounds with significant hydrophobic character, like (1-ethyl-3-piperidyl) 2,2-diphenylacetate, are often soluble in organic solvents but poorly soluble in water, making solvent selection critical for its effective use.

Interesting facts

Interesting Facts about (1-ethyl-3-piperidyl) 2,2-diphenylacetate

(1-ethyl-3-piperidyl) 2,2-diphenylacetate is a fascinating compound with unique properties and applications. Here are some noteworthy points about this compound:

  • Pharmacological Potential: This compound belongs to a class of compounds that have shown promise in various pharmacological applications, particularly in the field of medicinal chemistry. Research is ongoing to explore its potential as an analgesic or anti-inflammatory agent.
  • Structural Significance: The piperidine ring in the structure of (1-ethyl-3-piperidyl) 2,2-diphenylacetate contributes to its biological activity. The presence of both ethyl and diphenyl groups enhances lipophilicity, often leading to improved membrane permeability.
  • Synthetic Routes: The synthesis of this compound can involve several interesting chemical reactions, including esterification processes that are common in organic synthesis. Understanding the synthesis aids in the development of similar compounds for therapeutic uses.
  • Role in Research: As a subject of research, (1-ethyl-3-piperidyl) 2,2-diphenylacetate serves as a model for studying structure-activity relationships (SAR) within related chemical classes. SAR is an essential aspect of drug development that helps chemists optimize the effectiveness of compounds.
  • Application in Material Science: Beyond medicinal applications, this compound may find utility in material science, particularly in the development of polymers or coatings that possess desirable properties arising from its unique molecular structure.

In summary, the exploration of (1-ethyl-3-piperidyl) 2,2-diphenylacetate reveals its significance not just in pharmaceuticals, but also in broader scientific fields. As researchers delve deeper into its characteristics, we may uncover even more applications that highlight the compound's importance in chemistry.

Synonyms
piperidolate
82-98-4
1-Ethylpiperidin-3-yl 2,2-diphenylacetate
Dactil
Piperidolato
1-Ethyl-3-piperidyl diphenylacetate
N-Ethyl-3-piperidyl diphenylacetate
Piperidolatum
Piperidolate [INN:BAN]
Piperidolatum [INN-Latin]
Piperidolato [INN-Spanish]
JB 305
EINECS 201-449-7
Diphenylacetic acid, 1-ethyl-3-piperidyl ester
UNII-RJO31255V9
BRN 0031110
Piperidolate (INN)
3-Piperidinol, 1-ethyl-, diphenylacetate (ester)
1087 A.N.
RJO31255V9
(1-ethylpiperidin-3-yl) 2,2-diphenylacetate
ACETIC ACID, DIPHENYL-, 1-ETHYL-3-PIPERIDYL ESTER
JB-305
PIPERIDOLATE [MI]
PIPERIDOLATE [INN]
PIPERIDOLATE [WHO-DD]
1087-A.N.
DTXSID7048164
Benzeneacetic acid, alpha-phenyl-, 1-ethyl-3-piperidinyl ester
Benzeneacetic acid, .alpha.-phenyl-, 1-ethyl-3-piperidinyl ester
4-21-00-00028 (Beilstein Handbook Reference)
AN 1087
3-Piperidinol, 1-ethyl-, diphenylacetate
Dactil (TN)
Piperidolatum (INN-Latin)
Piperidolato (INN-Spanish)
Piperidolate?
Spectrum_001383
Piperidolate (Standard)
Prestwick0_001055
Prestwick1_001055
Prestwick2_001055
Prestwick3_001055
Spectrum2_001073
Spectrum3_001524
Spectrum4_000737
Spectrum5_001067
BSPBio_001010
BSPBio_002908
KBioGR_001034
KBioSS_001863
DivK1c_000112
SCHEMBL249131
SPBio_001086
SPBio_002935
BPBio1_001112
HY-B0962AR
CHEMBL1623992
DTXCID2027834
BDBM82378
CHEBI:91986
HY-B0962A
KBio1_000112
KBio2_001863
KBio2_004431
KBio2_006999
KBio3_002408
A03AA30
NINDS_000112
AAA08298
BCP31766
EX-A3194
NSC_4839
MFCD00242588
AKOS016013077
CS-4447
DB13351
CAS_82-98-4
IDI1_000112
1-Ethyl-3-piperidinyl diphenylacetate #
NCGC00178395-01
NCGC00178395-02
AC-35671
MS-24807
SBI-0051738.P002
(1-ethyl-3-piperidyl) 2,2-diphenylacetate
AB00053633
NS00001521
D08382
AB00053633_07
L001277
Q7197354
BRD-A97479839-003-05-9
BRD-A97479839-003-08-3
BRD-A97479839-003-13-3
2,2-diphenylacetic acid (1-ethyl-3-piperidinyl) ester
1087 A.N.; BRN 0031110; Dactil; JB 305; Piperidolatum
Benzeneacetic acid,.alpha.-phenyl-, 1-ethyl-3-piperidinyl ester
Benzeneacetic acid, alpha-phenyl-, 1-ethyl-3-piperidinyl ester (9CI)
201-449-7