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Azadirachtin

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Identification
Molecular formula
C35H44O16
CAS number
11141-17-6
IUPAC name
1-ethyl-10-[(1-hydroxycyclopropyl)methyl]-13,13-dimethyl-10-azatricyclo[7.3.1.02,7]trideca-2(7),3,5-trien-4-ol
State
State

Azadirachtin is typically found in a solid state at room temperature. It is a crystalline solid and is stable under normal conditions.

Melting point (Celsius)
154.50
Melting point (Kelvin)
427.60
Boiling point (Celsius)
536.70
Boiling point (Kelvin)
809.80
General information
Molecular weight
720.44g/mol
Molar mass
720.6480g/mol
Density
1.3300g/cm3
Appearence

Azadirachtin appears as a white to off-white powder or crystalline solid. It is often found as a white powder when isolated in its pure form.

Comment on solubility

Solubility of 1-ethyl-10-[(1-hydroxycyclopropyl)methyl]-13,13-dimethyl-10-azatricyclo[7.3.1.02,7]trideca-2(7),3,5-trien-4-ol

The solubility of the compound 1-ethyl-10-[(1-hydroxycyclopropyl)methyl]-13,13-dimethyl-10-azatricyclo[7.3.1.02,7]trideca-2(7),3,5-trien-4-ol, with the chemical formula C35H44O16, can be complex due to its sophisticated structure and functional groups. Here are some key considerations regarding its solubility:

  • Polar vs Nonpolar: This compound contains multiple hydroxyl (–OH) groups, which typically enhance solubility in polar solvents such as water.
  • Hydrophobic Interactions: The large nonpolar hydrocarbon segments may lead to hydrophobic interactions, potentially reducing solubility in aqueous solutions.
  • Cosolvents: It may require the inclusion of cosolvents or surfactants to improve solubility in water.
  • pH Dependence: Changes in pH can also affect the solubility due to the ionization of hydroxyl groups, influencing the compound's overall solubility profile.

As a general observation, it's often noted that:

  • Similar compounds tend to have solubility characteristics that can be predicted by their structure.
  • Experimental solubility tests are essential to determine practical solubility limits in specific solvents.

In conclusion, to fully understand the solubility of this intricate compound, it is imperative to conduct comprehensive solubility studies in various solvents under controlled conditions.

Interesting facts

Interesting Facts about 1-Ethyl-10-[(1-hydroxycyclopropyl)methyl]-13,13-dimethyl-10-azatricyclo[7.3.1.02,7]trideca-2(7),3,5-trien-4-ol

This unique compound boasts a complex structure that has garnered interest in the fields of medicinal and organic chemistry. Here are some intriguing aspects of this compound:

  • Complex Structure: The intricate arrangement of its molecular framework includes a tricyclic structure, which is essential for its biological activity. Its composition reflects a sophisticated blend of hydrogen, carbon, and oxygen, showcasing the beauty of organic molecules.
  • Potential Biological Activity: As a compound with multiple functional groups, it may exhibit significant pharmaceutical potential. Scientists are exploring its efficacy as a lead compound for drug development, particularly in areas like antitumor or antimicrobial activity.
  • Testing Stability: Due to its complex nature, understanding the stability and pathways for degradation of this compound is vital. Using advanced techniques such as NMR and mass spectrometry can help elucidate its behavior in various environments.
  • Research Opportunities: This compound presents a myriad of opportunities for exploration in synthetic organic chemistry. Its unique functional groups could inspire novel synthetic methodologies or cascade reactions in laboratory settings.
  • Interdisciplinary Interest: The study of such compounds often attracts chemists, biochemists, and pharmacologists alike, bridging the gaps between disciplines and pushing forward the boundaries of science.

In summary, 1-ethyl-10-[(1-hydroxycyclopropyl)methyl]-13,13-dimethyl-10-azatricyclo[7.3.1.02,7]trideca-2(7),3,5-trien-4-ol invites researchers to delve deeper into its properties, revealing a promising avenue for future scientific inquiry.

Synonyms
CHEMBL350384
71990-00-6
83829-76-9
Bremazocina
6-Ethyl-1,2,3,4,5,6-hexahydro-3-[(1-hydroxycyclopropyl)methyl]-11,11-dimethyl-2,6-methano-3-benzazocin-8-ol
(+/-)-Bremazocine
BREMAZOCINE(-)
SCHEMBL11246286
DTXSID50868536
BDBM50013388
NS00127153
L000925
Q4960506
1-ethyl-10-[(1-hydroxycyclopropyl)methyl]-13,13-dimethyl-10-azatricyclo[7.3.1.02,7]trideca-2(7),3,5-trien-4-ol
2,6-Methano-3-benzazocin-8-ol,6-ethyl-1,2,3,4,5,6-hexahydro-3-((1-hydroxycyclopropyl)methyl)-11,11-dimethyl
2,6-Methano-3-benzazocin-8-ol,6-ethyl-1,2,3,4,5,6-hexahydro-3-[(1-hydroxycyclopropyl)methyl]-11,11-dimethyl-, (2R)-
6-Ethyl-3-(1-hydroxy-cyclopropylmethyl)-11,11-dimethyl-1,2,3,4,5,6-hexahydro-2,6-methano-benzo[d]azocin-8-ol