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(1-ethyl-1-methylpiperidin-1-ium-3-yl) 2-hydroxy-2,2-diphenylacetate

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Identification
Molecular formula
C22H27NO3
IUPAC name
(1-ethyl-1-methyl-piperidin-1-ium-3-yl) 2-hydroxy-2,2-diphenyl-acetate
State
State

At room temperature, the compound is typically in a liquid state. It can exist as a solid form when cooled to lower temperatures, but maintains a liquid form under standard ambient conditions.

Melting point (Celsius)
84.00
Melting point (Kelvin)
357.15
Boiling point (Celsius)
412.00
Boiling point (Kelvin)
685.15
General information
Molecular weight
365.47g/mol
Molar mass
365.4690g/mol
Density
1.1130g/cm3
Appearence

The compound appears as a viscous liquid that is typically colorless to light yellow. It is usually clear but may appear slightly cloudy depending on its purity. The texture is often oily to the touch.

Comment on solubility

Solubility of (1-ethyl-1-methyl-piperidin-1-ium-3-yl) 2-hydroxy-2,2-diphenyl-acetate

The solubility of the compound (1-ethyl-1-methyl-piperidin-1-ium-3-yl) 2-hydroxy-2,2-diphenyl-acetate, with the chemical formula C22H27NO3, can be quite intriguing due to its unique structure and ionic nature. Here are some key points regarding its solubility:

  • Polar vs. Nonpolar: This compound contains several functional groups that may affect its solubility in different solvents. The presence of the piperidinium ion suggests that it may have polar characteristics, especially in aqueous environments.
  • Effect of Substituents: The two phenyl groups attached to the acetate moiety contribute to the compound's hydrophobic character, which may limit its solubility in polar solvents.
  • Aqueous Solubility: Due to the ionic nature of the piperidinium group, solubility in water might be moderate, though hindered by the bulky diphenyl substituents.
  • Organic Solvents: It may exhibit higher solubility in organic solvents such as ethanol, methanol, or dimethyl sulfoxide (DMSO), where the hydrophobic interactions are less of a barrier.

In summary, the solubility of this compound can be best understood by considering both its ionic and hydrophobic characteristics, which interact in different ways depending on the solvent. As a rule of thumb, *like dissolves like*, so the overall solubility will largely depend on the compatibility between the compound’s polar and nonpolar segments and the nature of the solvent used.

Interesting facts

Interesting Facts about (1-ethyl-1-methyl-piperidin-1-ium-3-yl) 2-hydroxy-2,2-diphenyl-acetate

The compound (1-ethyl-1-methyl-piperidin-1-ium-3-yl) 2-hydroxy-2,2-diphenyl-acetate is a fascinating example of an ionic liquid that combines both organic and pharmacological importance. Here are some intriguing points:

  • Concept of Ionic Liquids: Ionic liquids are salts that are liquid at room temperature. Due to their unique properties, they are often termed "green solvents," as they can replace toxic organic solvents in various reactions.
  • Pharmacological Potential: The piperidine structure is well-known in medicinal chemistry for its ability to interact with biological systems. Compounds like this may serve as intermediates in the synthesis of pharmaceuticals, affecting neurotransmitter systems and potentially acting as therapeutic agents.
  • Dual Functional Group: The presence of both a hydroxy and a diphenyl group in the acetate portion can lead to interesting reactivity options. This can make the compound relevant in organic synthesis and material science.
  • Versatile Applications: Research is ongoing into the use of similar compounds for applications in areas such as catalysis, electrochemistry, and even as smart materials, which can change properties based on external stimuli.
  • Sustainable Chemistry: There is a significant interest in developing ionic liquids that are not only effective but also have a minimal environmental impact, making them a focus in the field of sustainable chemistry.

To quote the words of many chemists, “The fusion of traditional chemistry with innovative materials science is paving the way for game-changing discoveries.” Compounds like (1-ethyl-1-methyl-piperidin-1-ium-3-yl) 2-hydroxy-2,2-diphenyl-acetate exemplify this innovative spirit as they hold potential for a variety of applications that could transform industries.

Synonyms
pipenzolate
13473-38-6
Pipenzolonum
Pipenzolate ion
Pipenzolate cation
UNII-RS3K5YXV34
EINECS 236-748-1
RS3K5YXV34
BRN 1506094
1-Ethyl-1-methyl-3-(oxidodiphenylacetoxy)piperidinium
PIPENZOLATE [WHO-DD]
DTXSID9048481
(1-ethyl-1-methylpiperidin-1-ium-3-yl) 2-hydroxy-2,2-diphenylacetate
5-21-01-00043 (Beilstein Handbook Reference)
Piperidinium, 1-ethyl-3-hydroxy-1-methyl-, benzilate (ester)
Piperidinium, 1-ethyl-3-((hydroxydiphenylacetyl)oxyl)-1-methyl-
1-Ethyl-3-hydroxy-1-methylpiperidinium bromide benzilate
1-ETHYL-3-HYDROXY-1-METHYLPIPERIDINIUM BENZILATE
1-ethyl-3-((2-hydroxy-2,2-diphenylacetyl)oxy)-1-methylpiperidin-1-ium
1-ETHYL-3-[(2-HYDROXY-2,2-DIPHENYLACETYL)OXY]-1-METHYLPIPERIDIN-1-IUM
Spectrum_001304
Prestwick0_000760
Prestwick1_000760
Prestwick2_000760
Prestwick3_000760
Spectrum2_001514
Spectrum3_001546
Spectrum4_000754
Spectrum5_001065
BSPBio_000780
BSPBio_002992
KBioGR_001108
KBioSS_001784
DivK1c_000638
SPBio_001587
SPBio_002719
BPBio1_000858
CHEMBL1619528
DTXCID5028455
SCHEMBL25957021
CHEBI:95178
KBio1_000638
KBio2_001784
KBio2_004352
KBio2_006920
KBio3_002492
NINDS_000638
WPUKUEMZZRVAKZ-UHFFFAOYSA-N
HY-B0953
DB13844
IDI1_000638
NCGC00018203-02
SBI-0051757.P002
AB00053816
NS00001167
AB00053816_15
AB00053816_16
Q2096435
BRD-A53561827-004-15-7
BRD-A53561827-004-22-3
BRD-A53561827-004-23-1
Piperidinium, 1-ethyl-3-((hydroxydiphenylacetyl)oxyl)-1-methyl-(9CI)
2-hydroxy-2,2-diphenylacetic acid (1-ethyl-1-methyl-3-piperidin-1-iumyl) ester
236-748-1