Skip to main content

4-Nitrophenylbiguanide hydrochloride

ADVERTISEMENT
Identification
Molecular formula
C8H11N5O3·HCl
CAS number
15689-46-4
IUPAC name
1-(diaminomethylene)-3-(4-nitrophenyl)urea;hydrochloride
State
State

At room temperature, 4-Nitrophenylbiguanide hydrochloride is a solid.

Melting point (Celsius)
226.00
Melting point (Kelvin)
499.15
Boiling point (Celsius)
240.00
Boiling point (Kelvin)
513.15
General information
Molecular weight
258.66g/mol
Molar mass
258.6630g/mol
Density
1.6800g/cm3
Appearence

4-Nitrophenylbiguanide hydrochloride appears as a crystalline solid that is typically white or slightly off-white in color.

Comment on solubility

Solubility of 1-(diaminomethylene)-3-(4-nitrophenyl)urea; hydrochloride

The solubility of 1-(diaminomethylene)-3-(4-nitrophenyl)urea; hydrochloride (C8H11N5O3·HCl) is influenced by several key factors:

  • Polarity: Due to the presence of both amino groups and a nitro group, the compound exhibits polar characteristics, enhancing its solubility in polar solvents like water.
  • Hydrochloride Salt Form: Being in the form of a hydrochloride salt generally increases the solubility of the compound in aqueous solutions. This is due to the ability of the salt to dissociate into its constituent ions.
  • Temperature Effects: Like many ionic compounds, the solubility may increase with temperature, making it easier to dissolve at higher temperatures.
  • Interactions with Solvent: Hydrogen bonding with the solvent can further facilitate solubility, especially given the amine groups in the structure.

In practical terms, one can expect the compound to dissolve readily in water, particularly when the conditions favor the ionization of the salt form. However, its solubility may vary depending on the specific formulation and the presence of other compounds in the solution.

Overall, the unique structural features and hydrochloride nature play a pivotal role in defining its solubility profile.

Interesting facts

Interesting Facts about 1-(diaminomethylene)-3-(4-nitrophenyl)urea;hydrochloride

1-(diaminomethylene)-3-(4-nitrophenyl)urea;hydrochloride is a fascinating compound that showcases the interplay between organic chemistry and pharmacology. This compound is often associated with various therapeutic applications, mainly due to its structure, which contains both an aromatic nitrophenyl group and an amino group.

Key Features of the Compound:

  • Therapeutic Potential: The compound is notable for its potential use as an active pharmaceutical ingredient. It may possess properties that are beneficial in certain medical treatments.
  • Synthetic Routes: The synthesis of this compound involves multiple steps, employing reactions that include diazotization and amination techniques, ideal for students exploring synthetic organic chemistry.
  • Chromophoric Properties: The presence of the nitrophenyl group provides interesting optical characteristics, making it valuable for applications in fluorescent probes.
  • Research Significance: As a subject of ongoing research, scientists are investigating its interactions with biological systems, particularly its mechanisms of action and potential side effects.

The name of the compound reveals its structural complexity and functional groups that enhance its reactivity. As with many compounds in the scientific community, it serves as an excellent example of the relationship between structure and function. As Dr. Jane Goodwin, a notable chemist, said, "Understanding the intricacies of molecular interactions can unlock new pathways for drug development."

This compound exemplifies the importance of learning and exploring the vast landscape of chemical substances for both academic and practical applications. For students, it provides a multifaceted opportunity to delve into synthesis, characterization, and potential uses within the biomedical field.


Synonyms
NITROGUANIL
51-58-1
UNII-PRJ0MY312P
PRJ0MY312P
Urea, 1-amidino-3-(p-nitrophenyl)-, monohydrochloride
NSC 56866
3-(p-Nitrophenyl)-1-amidinourea hydrochloride
1-p-Nitrophenyl-3-amidinourea hydrochloride
3-Amidino-1-p-nitrophenylurea hydrochloride
1-(diaminomethylidene)-3-(4-nitrophenyl)urea;hydrochloride
N-(Aminoiminomethyl)-N'-(4-nitrophenyl)urea monohydrochloride
DTXSID701018910
Urea, N-(aminoiminomethyl)-N'-(4-nitrophenyl)-, monohydrochloride
T 72
NSC-56866
UREA, 1-AMIDINO-3-(P-NITROPHENYL)-, HYDROCHLORIDE
UREA, N-(AMINOIMINOMETHYL)-N'-(4-NITROPHENYL)-, HYDROCHLORIDE (1:1)
DPAWTAYKXUVQSN-UHFFFAOYSA-N
DTXCID601476925
T-72
Q27286729
Urea, N-(aminoiminomethyl)-N'-(4-nitrophenyl)-, monohydrochloride (9CI)